Search
Search Results
-
Clinical effects of bacteremia in sepsis patients with community-acquired pneumonia
BackgroundData regarding the clinical effects of bacteremia on severe community-acquired pneumonia (CAP) are limited. Thus, we investigated clinical...
-
Clinical Efficacy of Megadose Vitamin C in Sepsis: Protocol for a Multicenter Randomized Single-Blind Placebo-Controlled Clinical Trial
IntroductionSepsis is a severe disease with a complex pathogenesis and is an important factor in the mortality of patients in intensive care units...
-
Time to treatment and mortality for clinical sepsis subtypes
BackgroundSepsis is common, deadly, and heterogenous. Prior analyses of patients with sepsis and septic shock in New York State showed a...
-
The spectrum of sepsis-associated encephalopathy: a clinical perspective
Sepsis-associated encephalopathy is a severe neurologic syndrome characterized by a diffuse dysfunction of the brain caused by sepsis. This review...
-
Sepsis-associated acute kidney injury: recent advances in enrichment strategies, sub-phenoty** and clinical trials
Acute kidney injury (AKI) often complicates sepsis and is associated with high morbidity and mortality. In recent years, several important clinical...
-
Pediatric Sepsis: New Strategies for Reducing Sepsis Related Mortality
Sepsis is one of the leading causes of morbidity and mortality in children. Timely recognition and management of sepsis with fluid resuscitation and...
-
Clinical Profile and Outcome of Neonates with Elizabethkingia Sepsis
Elizabethkingia, an emerging nosocomial pathogen is a gram-negative bacillus causing NICU outbreaks. This case series from a tertiary care hospital,...
-
One-year mortality prediction for patients with sepsis: a nomogram integrating lactic dehydrogenase and clinical characteristics
BackgroundTo explore the association between myocardial enzymes and one-year mortality, and establish a nomogram integrating myocardial enzymes and...
-
Altered intestinal microbiome and metabolome correspond to the clinical outcome of sepsis
BackgroundThe gut microbiome plays a pivotal role in the progression of sepsis. However, the specific mechanism of gut microbiota and its metabolites...
-
Triggering receptor expressed on myeloid cells-1 in sepsis, and current insights into clinical studies
Triggering receptor expressed on myeloid cells-1 (TREM-1) is a pattern recognition receptor and plays a critical role in the immune response. TREM-1...
-
ATPergic signaling disruption in human sepsis as a potential source of biomarkers for clinical use
Sepsis is a life-threatening organ dysfunction caused by a dysregulated inflammatory response to infection. To date, there is no specific treatment...
-
Neurofilament light chains to assess sepsis-associated encephalopathy: Are we on the track toward clinical implementation?
Sepsis is the most common cause of admission to intensive care units worldwide. Sepsis patients frequently suffer from sepsis-associated...
-
Predicting sepsis in-hospital mortality with machine learning: a multi-center study using clinical and inflammatory biomarkers
BackgroundThis study aimed to develop and validate an interpretable machine-learning model that utilizes clinical features and inflammatory...
-
The evolving value of older biomarkers in the clinical diagnosis of pediatric sepsis
AbstractSepsis remains the leading cause of childhood mortality worldwide. The evolving definition of pediatric sepsis is extrapolated from adult...
-
Application of Machine Learning for Clinical Subphenotype Identification in Sepsis
IntroductionSepsis is a heterogeneous clinical syndrome. Identification of sepsis subphenotypes could lead to allowing more precise therapy. However,...
-
Patient diversity and author representation in clinical studies supporting the Surviving Sepsis Campaign guidelines for management of sepsis and septic shock 2021: a systematic review of citations
BackgroundThe generalizability of the Surviving Sepsis Campaign (SSC) guidelines to various patient populations and hospital settings has been...
-
Assessment of systemic circulation using ultrasound Doppler in late onset neonatal sepsis and its clinical correlation: an observational study
ObjectivesTo measure the Doppler velocimetry parameters in the anterior cerebral artery (ACA), superior mesenteric artery (SMA), and main renal...
-
Clinical sepsis phenotypes in critically ill COVID-19 patients
BackgroundA greater understanding of disease heterogeneity may facilitate precision medicine for coronavirus disease 2019 (COVID-19). Previous work...
-
Impact of P2Y12 inhibitors on clinical outcomes in sepsis-3 patients receiving aspirin: a propensity score matched analysis
BackgroundSepsis is a life-threatening disease accompanied by disorders of the coagulation and immune systems. P2Y12 inhibitors, widely used for...
-
Clinical and time-related predictors of sepsis in patients with obstructive uropathy due to ureteral stones in the emergency setting
PurposeWell-defined clinical predictors of sepsis after upper tract drainage for obstructive uropathy due to ureteral stones are needed. We aim to...