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Assessment of clinical relevance of antigen improves diagnostic accuracy of hypersensitivity pneumonitis
BackgroundExposure assessment is integral to the diagnosis of hypersensitivity pneumonitis (HP). Although the clinical relevance of exposed antigens...
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Correlation Aware Relevance-Based Semantic Index for Clinical Big Data Repository
In this paper, we focus on indexing mechanisms for unstructured clinical big integrated data repository systems. Clinical data is unstructured and...
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Clinical Relevance of Radial Scars: A Review of the Current Literature
Purpose of ReviewThe objective of this review was to examine the current literature and clinical relevance of radial scars. We discuss the diagnostic...
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A new groin hernia classification with clinical relevance
IntroductionGroin hernia is one of the most commonly managed surgical diseases around the world. The typical question asked by patients is “Does my...
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The clinical relevance of different antiphospholipid antibody profiles in pediatric rheumatology patients
BackgroundThe clinical relevance of different antiphospholipid antibody (aPL) profiles, including low level anticardiolipin (aCL) and anti-β 2 -glycopr...
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MCID and PASS in Knee Surgeries. Theoretical Aspects and Clinical Relevance References
The application and interpretation of patient-reported outcome measures (PROM), following knee injuries, pathologies, and interventions, can be...
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Looking for RET alterations in thyroid cancer: clinical relevance, methodology and timing
PurposeThyroid carcinoma (TC) is a rare neoplasia of the endocrine system and account for about 2–3% of all human tumors. According to their cell...
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Clinical relevance of tumour-associated macrophages
In the past decade, substantial advances have been made in understanding the biology of tumour-associated macrophages (TAMs), and their clinical...
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Clinical relevance of Staphylococcus saccharolyticus detection in human samples: a retrospective cohort study
PurposeTo characterize the clinical relevance of S. saccharolyticus and to identify criteria to distinguish between infection and contamination.
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Clinical relevance of PD-1 positive CD8 T-cells in gastric cancer
BackgroundWe evaluated the relevance of PD-1 + CD8 + T-cells in gastric cancer (GC) including prognostic significance, association with chemotherapy...
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Clinical relevance of double heterozygosity revealed by next-generation sequencing of homologous recombination repair pathway genes in South African breast cancer patients
PurposeGenetically predisposed breast cancer (BC) patients represent a minor but clinically meaningful subgroup of the disease, with 25% of all cases...
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Evaluation of the clinical relevance of the Biofire© FilmArray pneumonia panel among hospitalized patients
PurposePanel PCR tests provide rapid pathogen identification. However, their diagnostic performance is unclear. We assessed the performance of the...
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Contrast-induced encephalopathy—neuroimaging findings and clinical relevance
Contrast-induced encephalopathy (CIE) is a rare encephalopathic condition after the administration of a contrast agent. The diagnosis of CIE is...
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Corona mortis: clinical evaluation of prevalence, anatomy, and relevance in anterior approaches to the pelvis and acetabulum
PurposeTo evaluate the clinical prevalence, characteristics, and relevance of the corona mortis (CM) in anterior approaches to the pelvis and...
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Clinical relevance of reversible cerebral vasoconstriction syndrome in pregnant women with posterior reversible encephalopathy syndrome: review of case reports in Japan
We systematically reviewed case reports of posterior reversible encephalopathy syndrome (PRES), and investigated the characteristics of PRES in...
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The clinical relevance of human papillomavirus negative status in unsatisfactory cervical cytology
PurposeThe aim of this study was to evaluate the clinical relevance of high-risk human papillomavirus (HR-HPV) negativity at the time of...
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A molecular characterization and clinical relevance of microglia-like cells derived from patients with panic disorder
Few studies report the microglia involvement in the pathogenesis of panic disorder (PD), although the crucial role of microglia in other...
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The interobserver reliability of clinical relevance in orthopaedic research
PurposeA ratio of observed difference (OD) over the 95% confidence interval (CI) has been shown to be strongly associated with the perceived clinical...
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The characteristics and clinical relevance of tumor fusion burden in non-EBV (+) gastric cancer with MSS
BackgroundNext-generation sequencing (NGS) is maturely applied for gene fusion detection. Although tumor fusion burden (TFB) has been identified as...
