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CT findings and clinical characteristics in distinguishing renal urothelial carcinoma mimicking renal cell carcinoma from clear cell renal cell carcinoma
BackgroundWe aimed to characterize the clinical and multiphase computed tomography (CT) features, which can distinguish renal urothelial carcinoma...
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Differentiation between renal epithelioid angiomyolipoma and clear cell renal cell carcinoma using clear cell likelihood score
PurposeClear cell likelihood score (ccLS) may be a reliable diagnostic method for distinguishing renal epithelioid angiomyolipoma (EAML) and clear...
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Clear cell and non-clear cell renal cell carcinoma in young adults: clinicopathological features, survival outcomes and prognostic factors
ObjectivesRenal cell carcinoma (RCC) is infrequent among young adults. Few studies reported the outcome of RCC in young adults by pathological...
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Von Hippel–Lindau protein signalling in clear cell renal cell carcinoma
The distinct pathological and molecular features of kidney cancer in adaptation to oxygen homeostasis render this malignancy an attractive model for...
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Evaluation of a multiparametric renal CT algorithm for diagnosis of clear-cell renal cell carcinoma among small (≤ 4 cm) solid renal masses
ObjectiveTo evaluate a recently proposed CT-based algorithm for diagnosis of clear-cell renal cell carcinoma (ccRCC) among small (≤ 4 cm) solid renal...
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SLFN11 promotes clear cell renal cell carcinoma progression via the PI3K/AKT signaling pathway
SLFN11 is abnormally expressed and associated with survival outcomes in various human cancers. However, the role of SLFN11 in clear cell renal cell...
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Downregulation of UBB potentiates SP1/VEGFA-dependent angiogenesis in clear cell renal cell carcinoma
Clear cell renal cell carcinoma (ccRCC) presents a unique profile characterized by high levels of angiogenesis and robust vascularization....
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Qualitative and quantitative assessment of non-clear cell renal cell carcinoma using contrast-enhanced ultrasound
BackgroundNon-clear cell renal cell carcinoma (nccRCC) represents a rare form of renal cell carcinoma (RCC) in the clinic. It is now understood that...
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Update on systemic therapy for clear cell renal cell carcinoma
The treatment landscape of advanced and metastatic renal cell carcinoma (RCC) has changed fundamentally over the last two decades with the...
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Exploring oncogenes for renal clear cell carcinoma based on G protein-coupled receptor-associated genes
G protein-coupled receptors (GPCRs) are a class of receptors on cell membranes that regulate various biological processes in cells, such as cell...
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Bioinformatics analysis identifies GLUD1 as a prognostic indicator for clear cell renal cell carcinoma
BackgroundRenal cell carcinoma (RCC) is a common primary tumor of the kidney and is divided into three major subtypes, of which clear cell renal cell...
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KL is a favorable prognostic factor related immune for clear cell renal cell carcinoma
BackgroundClear cell renal cell carcinoma (ccRCC) is a prevalent cancer in adult urology, often leading to metastasis and poor prognosis. Recently,...
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TREM-1 as a potential prognostic biomarker associated with immune infiltration in clear cell renal cell carcinoma
BackgroundThe tumor immune microenvironment plays a crucial role in the efficacy of various therapeutics. However, their correlation is not yet...
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Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma
Loss of function of the von Hippel-Lindau (VHL) tumor suppressor gene is a hallmark of clear cell renal cell carcinoma (ccRCC). The importance of...
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Regional differences in clear cell metastatic renal cell carcinoma patients across the USA
PurposeTo test for regional differences in clear cell metastatic renal cell carcinoma (ccmRCC) patients across the USA.
MethodsThe Surveillance,...
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Comparative diagnostic performance of contrast-enhanced ultrasound and dynamic contrast-enhanced magnetic resonance imaging for differentiating clear cell and non-clear cell renal cell carcinoma
ObjectiveTo compare the diagnostic efficiency of contrast-enhanced ultrasound (CEUS) with that of dynamic contrast-enhanced magnetic resonance...
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ZNF692 promotes the migration and response to immunotherapy of clear cell renal cell carcinoma cells by targeting metabolic pathway
Clear cell renal cell carcinoma (ccRCC), with high mortality and poor prognosis, is the most common type of renal malignancy. It is necessary to...
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Aldolase B attenuates clear cell renal cell carcinoma progression by inhibiting CtBP2
Aldolase B (ALDOB), a glycolytic enzyme, is uniformly depleted in clear cell renal cell carcinoma (ccRCC) tissues. We previously showed that ALDOB...
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LncRNA LBX2-AS1 promotes proliferation and migratory capacity of clear cell renal cell carcinoma through mitophagy
BackgroundLong non-coding RNAs (lncRNAs) have been extensively investigated in the field of cancer, among which, lncRNA ladybird homeobox 2-antisense...
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Dynamic changes of SCGN expression imply different phases of clear cell renal cell carcinoma progression
The secretagogin (SCGN) was originally identified as a secreted calcium-binding protein present in the cytoplasm. Recent studies have found that SCGN...