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Bilateral Sudden Irreversible Hearing Loss in a Case of Chronic Myeloid Leukaemia: A Case Report
Chronic myeloid leukemia is a type of blood cancer that affects the bone marrow and results in an overproduction of immature WBCs. The genetic...
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Questions concerning tyrosine kinase-inhibitor therapy and transplants in chronic phase chronic myeloid leukaemia
In this provocative commentary, we consider several questions posed by the late chronic myeloid leukaemia (CML) expert Prof. Michele Baccarani, which...
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SARS-CoV-2 Omicron BA.5.2-infection and COVID-19 in persons with chronic myeloid leukaemia
ObjectiveA SARS-CoV-2 Omicron (BA.5.2) epidemic began in China in December, 2022 following stop** the zero COVID policy.
MethodsWe studied...
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The prevalence of hepatic and thyroid toxicity associated with imatinib treatment of chronic myeloid leukaemia: a systematic review
BackgroundImatinib, a potent inhibitor of targeted protein tyrosine kinases, treats chronic myeloid leukaemia (CML). Data on imatinib-associated...
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Incidence and immunophenotype of abnormal lymphoblast populations at diagnosis of chronic myeloid leukaemia in chronic phase
Chronic myeloid leukaemia most commonly presents in chronic phase (CML-CP) and it is characterised by granulocytic proliferation. Many patients have...
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Death due to unsuspected acute myeloid leukaemia: an unusual forensic diagnosis
Acute myeloid leukaemia (AML) is a rare haematologic cancer with a rapid increase in blast cells, which need to be rapidly diagnosed and treated. The...
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Outcomes and prognosis of haploidentical haematopoietic stem cell transplantation in children with FLT3-ITD mutated acute myeloid leukaemia
The presence of internal tandem duplication mutations in the FMS-like tyrosine kinase 3 receptor ( FLT3-ITD ) is a poor prognostic predictor in...
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Co-variates associated with outcomes of tyrosine kinase-inhibitor therapy in persons with chronic myeloid leukaemia initially presenting in accelerated phase
We interrogated data from 278 consecutive subjects with chronic myeloid leukaemia (CML) presenting in accelerated phase diagnosed by European...
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Survival with chronic myeloid leukaemia after failing milestones
Therapy after failing response milestones in CML is controversial. Risks associated with comorbidities, drug toxicities or transplantation may...
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Personality traits favourable for non-adherence to treatment in patients with chronic myeloid leukaemia: role of type A and D personality
BackgroundThe introduction of BCR-ABL tyrosine kinase inhibitors (TKIs) to chronic myeloid leukemia (CML) therapy has revolutionized the treatment of...
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Updated comparable efficacy of cord blood transplantation for chronic myelomonocytic leukaemia: a nationwide study
Chronic myelomonocytic leukaemia (CMML) is a haematological malignancy with a poor prognosis. Allogeneic haematopoietic stem cell transplantation...
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Allogeneic hematopoietic stem cell transplantation for adults with therapy-related acute myeloid leukaemia: a retrospective multicentre study on behalf of the SFGM-TC
We report the results from a multicentre retrospective study of 220 adult patients who underwent allogeneic hematopoietic stem cell transplantation...
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Chronic myeloid leukaemia (CML) presenting in B-lymphoblastic crisis: a diagnostic challenge
We report the case of a 75-year-old female presented with lethargy, Hb 93 g/L, WBC 64 x 10 9 /L, platelet 110 x 10 9 /L. Blood film showed blasts,...
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Metabolic plasticity in blast crisis-chronic myeloid leukaemia cells under hypoxia reduces the cytotoxic potency of drugs targeting mitochondria
Metabolic reprogramming (MR) influences progression of chronic myeloid leukaemia (CML) to blast crisis (BC), but metabolic programs may change...
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Impact of the treatment of chronic myeloid leukaemia by tyrosine-kinase inhibitors on sick leaves refund: a nationwide cohort study
BackgroundThe advent of chronic myeloid leukaemia (CML) tyrosine-kinase inhibitors (TKI) has led to new paradigms including occupational...
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Pathogenesis and Treatment of Leukemia
This book covers a comprehensive update on acute and chronic leukemia. In 54 chapters, authors introduce research progress and clinical trials of...