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Bone mineral density is increased in the cadmium-induced omphalocele chick model by using three-dimensional micro-computed tomography
PurposeThe cadmium (Cd) chick model has been described as a reliable model of omphalocele. Skeletal anomalies, including lumber lordosis, can be seen...
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Multi-disciplinary Insights from the First European Forum on Visceral Myopathy 2022 Meeting
Visceral myopathy is a rare, life-threatening disease linked to identified genetic mutations in 60% of cases. Mostly due to the dearth of knowledge...
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Novel drug delivery systems of Chinese medicine for the treatment of inflammatory bowel disease
Inflammatory bowel disease (IBD) is an idiopathic intestinal inflammatory disease that comprises ulcerative colitis (UC) and Crohn’s disease (CD)....
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Percutaneous treatment of symptomatic deep vein thrombosis in adolescents using large-bore thrombectomy systems
BackgroundWhile large-bore mechanical thrombectomy provides effective venous thrombus removal, often with avoidance of thrombolytics, literature...
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Repurposing sarecycline for osteoinductive therapies: an in vitro and ex vivo assessment
IntroductionTetracyclines (TCs) embrace a class of broad-spectrum antibiotics with unrelated effects at sub-antimicrobial levels, including an...
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Myelomeningocele: the evolution of care over the last 50 years
PurposeMyelomeningocele (MMC) is one of the representative anomalies in the field of pediatric neurosurgery. During the 50 years of ISPN history, MMC...
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Amniotic fluid absorption and growth functions in humans: what can we indirectly learn from congenital digestive atresias?
BackgroundAmniotic fluid (AF) was thought of just as a mechanical cushioning to the foetus. Nowadays, its role during pregnancy is getting more...
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A successful centre for translational paediatric surgical research
The National Children’s Research Centre (NCRC), the single largest paediatric research centre in Ireland, has been in existence for over 50 years...
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State of the art in translating experimental myelomeningocele research to the bedside
Myelomeningocele (MMC), the commonest type of spina bifida (SB), occurs due to abnormal development of the neural tube and manifest as failure of the...
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What Causes Desmoplastic Reaction in Small Intestinal Neuroendocrine Neoplasms?
Purpose of ReviewMesenteric desmoplasia in small intestinal neuroendocrine neoplasms (SINENs) is associated with increased morbidity and mortality....
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Role of interventional radiology in management of post-liver transplant anastomotic complications
BackgroundLiver transplantation is considered to be the treatment of choice in cases of end-stage liver disease; however, as a major procedure, the...
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GFRA4 improves the neurogenic potential of enteric neural crest stem cells via hedgehog pathway
BackgroundHirschsprung disease (HSCR) is a congenital intestinal disease characterised by functional obstruction of the colon. Herein, we...
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Skip segment Hirschsprung’s disease: report of two rare cases and management
PurposeSkip segment Hirschsprung’s disease (SS-HSCR) is defined as the occurrence of a segment of ganglionated intestine surrounded proximally and...
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Rigid forceps and excimer laser use for complex inferior cava filter retrieval: a preliminary quantitative analysis of available evidence
PurposeThe present study aims to evaluate the safety and efficacy of advanced inferior vena cava filter (IVCF) retrieval using laser assistance...
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Towards a clinically-based common coordinate framework for the human gut cell atlas: the gut models
BackgroundThe Human Cell Atlas resource will deliver single cell transcriptome data spatially organised in terms of gross anatomy, tissue location...
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Evaluation and management of biliary complications after pediatric liver transplantation: pearls and pitfalls for percutaneous techniques
In pediatric liver transplantation, bile duct complications occur with a greater incidence than vascular anastomotic dysfunction and represent a...
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Portomesenteric and portosystemic venous reconstructions in children using balloon-expandable endoprostheses
BackgroundPortomesenteric and portosystemic venous occlusive disease may lead to portomesenteric hypertension, variceal bleeding, ascites and...
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New Challenges in Drug Allergy: the Resurgence of Excipients
Purpose of ReviewAllergy to excipients is a cause of multidrug allergy and if it is not taken into account, it can lead to unexpected severe...
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Mobile colistin resistance (mcr-1) gene-positive Escherichia coli from chickens in Nigeria is potentially pathogenic and transfers colistin resistance to other organisms
Colonization of chicken gut by pathogenic Escherichia coli harboring mobile colistin resistance ( mcr -1) gene is a huge public and animal health risk....
