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Effects of Chemoradiation Therapy on Hearing in Patients with Malignancy of Head and Neck
Purpose: To study effects of chemoradiation therapy on hearing in patients with malignancy of head and neck. Methods and materials: Patients...
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Total Neoadjuvant Therapy in Rectal Cancer: Multi-center Comparison of Induction Chemotherapy and Long-Course Chemoradiation Versus Short-Course Radiation and Consolidative Chemotherapy
BackgroundTotal neoadjuvant therapy for locally advanced rectal cancer may include induction chemotherapy and chemoradiation or short-course...
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Is There a Role for Adjuvant Chemotherapy in Pathologic Node-Negative Locally Advanced Rectal Cancer After Neoadjuvant Chemoradiation Therapy?
BackgroundNeoadjuvant chemoradiation therapy (NCRT, 5-fluorouracil and radiation) followed by resection and adjuvant chemotherapy (AC) is one of the...
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Prediction of locally advanced rectal cancer response to neoadjuvant chemoradiation therapy using volumetric multiparametric MRI-based radiomics
PurposeTo assess the role of pretreatment multiparametric (mp)MRI-based radiomic features in predicting pathologic complete response (pCR) of locally...
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Adjuvant Chemoradiation in Resected Biliary Adenocarcinoma: Evaluation of SWOG S0809 with a Large National Database
BackgroundThere is a paucity of evidence supporting the use of adjuvant radiation therapy in resected biliary cancer. Supporting evidence for use...
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Completely Resectable (cT1-2) Esophageal Squamous Cell Carcinoma with Minimal Lymph Node Involvement (cN1): Is Neoadjuvant Chemoradiation Therapy the Only Viable Treatment Option?
BackgroundNeoadjuvant chemoradiation therapy (nCRT) is recommended when lymph node metastasis is evident or strongly suspected on preoperative...
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MRI radiomics signature to predict lymph node metastasis after neoadjuvant chemoradiation therapy in locally advanced rectal cancer
PurposeTo investigative the performance of MRI-radiomics analysis derived from T2WI and apparent diffusion coefficients (ADC) images before and after...
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Longitudinal extensive transverse myelitis after chemoradiation therapy with durvalumab, a rare complication: case report
BackgroundLongitudinal extensive transverse myelitis is a rare and potentially life-threatening complication of chemoradiation. Certain chemotherapy...
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Influence of chemoradiation on the immune microenvironment of cervical cancer patients
PurposeCervical cancer remains a leading cause of cancer death in women. While immunotherapy has shown great success in combating cancer, the value...
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Penile-scrotal erythrodysesthesia among rectal cancer patients receiving fluoropyrimidine-based chemoradiation: a case report series
BackgroundPalmar-plantar erythrodysesthesia (PPE) is a slowly develo** cutaneous reaction commonly experienced by patients treated with...
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Effect of Pneumocystis jirovecii pneumonia prophylaxis on hematologic toxicity in patients receiving chemoradiation for primary brain tumors
PurposeDiffuse gliomas are managed with radiation and temozolomide; however, this therapy often results in hematologic toxicities. Patients...
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Primary squamous cell carcinoma of the thyroid treated with concurrent chemoradiation and palliative immunotherapy: a case report
BackgroundPrimary squamous cell carcinoma of the thyroid is a very rare malignancy with aggressive growth and poor prognosis. There is currently no...
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Long-term treatment outcomes of temozolomide-based chemoradiation in patients with adult-type diffuse IDH-mutant grade 2 astrocytoma
PurposeTo report the long-term outcomes in adult patients with grade 2 IDH-mutant astrocytoma treated with temozolomide (TMZ)-based chemoradiation....
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Quality of life following concurrent temozolomide-based chemoradiation therapy or observation in low-grade glioma
PurposeLow-grade glioma (LGG) exhibits longer median survival than high-grade brain tumors, and thus impact of our therapies on patient quality of...
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Cognitive function after concurrent temozolomide-based chemoradiation therapy in low-grade gliomas
PurposeWe sought to evaluate the effects of concurrent temozolomide-based chemoradiation therapy on neurocognitive function in patients with...
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Estimating Risk of Locoregional Failure and Overall Survival in Anal Cancer Following Chemoradiation: A Machine Learning Approach
BackgroundOptimal treatment of anal squamous cell carcinoma (ASCC) is definitive chemoradiation. Patients with persistent or recurrent disease...
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Longer Time Interval from Neoadjuvant Chemoradiation to Surgery is Associated with Poor Survival for Patients Without Clinical Complete Response in Oesophageal Cancer
BackgroundThe optimal interval between neoadjuvant therapy and oesophagectomy for oesophageal cancer remains controversial.
MethodsPatients with...
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Psychosocial consequences of head and neck cancer symptom burden after chemoradiation: a mixed-method study
PurposePatients with head and neck cancer (HNC) experience significant symptom burden from combination chemotherapy and radiation (chemoradiation)...
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Impact of Delaying Surgery After Chemoradiation on Outcomes for Locally Advanced Esophageal Squamous Cell Carcinoma
BackgroundPerforming selective esophagectomy for locally advanced squamous cell carcinoma may spare patients morbidity, but delayed surgery may infer...
