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Diagnostic accuracy of the Xpert® MTB/XDR assay for detection of Isoniazid and second-line antituberculosis drugs resistance at central TB reference laboratory in Tanzania
IntroductionEarly diagnosis of tuberculosis (TB) and universal access to drug-susceptibility testing (DST) are critical elements of the WHO End TB...
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Spaceflight and the Central Nervous System Clinical and Scientific Aspects
This book consolidates the current knowledge of how short and long-duration spaceflight affects the anatomy and physiology of the central nervous...
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Cytogenetics analysis as the central point of genetic testing in acute myeloid leukemia (AML): a laboratory perspective for clinical applications
Chromosomal abnormalities in acute myeloid leukemia (AML) have significantly contributed to scientific understanding of its molecular pathogenesis,...
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What proportion of embryos should be considered for transfer following a mosaic diagnosis? A study of 115 clinics from a central diagnostic laboratory
PurposeThe aim of this study is to identify what proportion of mosaic embryo diagnoses should be considered for transfer, and thereby assess the...
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The role of laboratory investigations in the classification of tremors
IntroductionTremor is the most common movement disorder. Although clinical examination plays a significant role in evaluating patients with tremor,...
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Correlation Between Imaging Morphological Findings and Laboratory Biomarkers in Patients with Retinal Vein Occlusion
IntroductionThe aim of this study was to investigate the possible correlation between peripheral blood biomarkers and morphological characteristics...
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Clinical, Epidemiological, and Laboratory Features of Mayaro Virus Infection: a Systematic Review
Purpose of ReviewMayaro virus is an arbovirus that circulates in a wild cycle transmitted by Haemagogus janthinomys ; however, case reports in urban...
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Cutting-edge technology and automation in the pathology laboratory
One of the goals of pathology is to standardize laboratory practices to increase the precision and effectiveness of diagnostic testing, which will...
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Laboratory diagnosis of CNS infections in children due to emerging and re-emerging neurotropic viruses
AbstractRecent decades have witnessed the emergence and re-emergence of numerous medically important viruses that cause central nervous system (CNS)...
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Association between common laboratory indices and IgAV recurrence in children
BackgroundIgA vasculitis (IgAV) is a common type of vasculitis seen in children. IgAV recurrence can result in chronic kidney disease. We aimed to...
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Interventions to improve appropriateness of laboratory testing in the intensive care unit: a narrative review
Healthcare expenses are increasing, as is the utilization of laboratory resources. Despite this, between 20% and 40% of requested tests are deemed...
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Associations between Outpatient Laboratory Test Age and Healthcare Utilization in Type 2 Diabetes Care
PurposeTo examine the longitudinal relationship between the age or shelf-life of common type 2 diabetes laboratory tests for serum creatinine,...
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Bilateral central serous retinal detachment in a patient with nephrotic syndrome: a case report
BackgroundThe aim of this report is to highlight the importance of considering nephrotic syndrome as a potential underlying cause of bilateral...
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Neurobrucellosis: laboratory features, clinical characteristics, antibiotic treatment, and clinical outcomes of 21 patients
BackgroundNeurobrucellosis (NB) is a rare and serious complication of brucellosis. Its clinical manifestations vary, with no obvious specificity. At...
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Initial laboratory validation of temperature development models for Necrodes littoralis L. (Staphylinidae: Silphinae)
Development models of necrophagous insects are applied in forensic entomology for post-mortem interval estimation. Such estimates may be used as...
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Septic Shock, Tubular Necrosis, and Central Diabetes Insipidus: A Challenging Syndrome
BackgroundThe association between septic shock, acute tubular necrosis, and central diabetes insipidus is infrequent: our recent clinical observation...
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Survey of Laboratory Medicine’s national response to the HSE cyberattack in the Republic of Ireland
BackgroundOn Friday 14 May 2021, the Health Service Executive (HSE) was subjected to a serious cyberattack on their information technology (IT)...
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The prevalence and polysomnographic characteristics of treatment-emergent central sleep apnea with obstructive sleep apnea
PurposeTo investigate the prevalence of treatment-emergent central sleep apnea (TECSA) in individuals with obstructive sleep apnea syndrome (OSAS)...
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A rare presentation of central pontine myelinolysis secondary to hyperglycaemia
BackgroundCentral pontine myelinolysis (CPM) is a rare demyelinating disorder caused by the loss of myelin in the center of the basis pontis. CPM...
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A prospective observational study on impact of epinephrine administration route on acute myocardial infarction patients with cardiac arrest in the catheterization laboratory (iCPR study)
BackgroundEpinephrine is routinely utilized in cardiac arrest; however, it is unclear if the route of administration affects outcomes in acute...
