Search
Search Results
-
Circulating tumor cell detection: A prospective comparison between CellSearch® and RareCyte® platforms in patients with progressive metastatic breast cancer
PurposeCirculating tumor cells (CTCs) are prognostic in patients with breast cancer. Several technical platforms exist for their enumeration and...
-
A multiparameter liquid biopsy approach allows to track melanoma dynamics and identify early treatment resistance
Melanoma heterogeneity is a hurdle in metastatic disease management. Although the advent of targeted therapy has significantly improved patient...
-
Relationship of Ki-67 index in biopsies of metastatic breast cancer tissue and circulating tumor cells (CTCs) at the time of biopsy collection
BackgroundThe proliferation marker Ki-67 is a major pathological feature for the description of the state of disease in breast cancer. It helps to...
-
Circulating tumor cell quantification during abiraterone plus prednisone therapy may estimate survival in metastatic castration-resistant prostate cancer patients
PurposeCirculating tumor cells (CTCs) predict survival in response to different interventions in metastatic castration-resistant prostate cancer...
-
How previous treatment changes the metabolomic profile in patients with metastatic breast cancer
PurposeMetabolites are in the spotlight of attention as promising novel breast cancer biomarkers. However, no study has been conducted concerning...
-
Quantitative assessment of circulating tumor cells in cerebrospinal fluid as a clinical tool to predict survival in leptomeningeal metastases
PurposeCirculating tumor cells in cerebrospinal fluid are a quantitative diagnostic tool for leptomeningeal metastases from solid tumors, but their...
-
Trastuzumab and first-line taxane chemotherapy in metastatic breast cancer patients with a HER2-negative tumor and HER2-positive circulating tumor cells: a phase II trial
PurposeHER2 overexpressing circulating tumor cells (CTCs) are observed in up to 25% of HER2-negative metastatic breast cancer patients. Since...
-
Circulating tumor cells clusters and their role in Breast cancer metastasis; a review of literature
Breast cancer is a significant and deadly threat to women globally. Moreover, Breast cancer metastasis is a complicated process involving multiple...
-
Clinical significance of circulating tumor cells in the response to trastuzumab for HER2-negative metastatic gastric cancer
PurposeThe prognosis of metastatic gastric cancer has improved due to trastuzumab in patients with HER2 positive. Circulating tumor cells (CTCs) have...
-
The functional and clinical roles of liquid biopsy in patient-derived models
The liquid biopsy includes the detection of circulating tumor cells (CTCs) and CTC clusters in blood, as well as the detection of, cell-free DNA...
-
Dynamic changes of CTCs in patients with metastatic HR(+)/HER2(−) breast cancer receiving salvage treatment with everolimus/exemestane
PurposeDetection of CTCs represents a poor prognostic factor in patients with early and metastatic breast cancer (mBC) and treatment with...
-
Diagnostic liquid biopsy biomarkers in renal cell cancer
The clinical presentation of renal cell cancer (RCC) is shifting towards incidental and early detection, creating new challenges in RCC diagnosis....
-
Detection and identification of circulating tumor cells in parathyroid tumors and correlation analysis with clinicopathological features
IntroductionThe differential diagnosis of parathyroid carcinoma (PC)/parathyroid adenoma (PA) in parathyroid tumors is critical for their management...
-
Longitudinal tracking of circulating rare events in the liquid biopsy of stage III–IV non-small cell lung cancer patients
In the United States, lung cancer is the second most common type of cancer with non-small cell lung cancer (NSCLC) encompassing around 85% of total...
-
Circulating tumor cells, circulating tumor DNA, and disease characteristics in young women with metastatic breast cancer
BackgroundClinical and genomic data from patients with early-stage breast cancer suggest more aggressive disease in premenopausal women. However, the...
-
Perioperative change of circulating tumor cells in cytoreductive radical prostatectomy for oligometastatic hormone-sensitive prostate cancer: the preliminary safety evidence from long-term oncologic outcomes
Surgical manipulation has a risk of triggering the shedding of circulating tumor cells (CTCs) in patients with malignancies, However, perioperative...
-
„Liquid biopsy“ – schon reif für Therapieentscheidungen?
Liquid biopsy (LB)-based methods enable less invasive and repeatable sample collection from various body fluids of cancer patients including blood,...
-
An overview of current development and barriers on liquid biopsy in patients with early-stage non-small-cell Lung cancer
PurposeLiquid biopsy is a promising technological method in patient management of early-stage non-small-cell lung cancer (NSCLC). The detection...
-
Cerebrospinal fluid circulating tumor cells as a quantifiable measurement of leptomeningeal metastases in patients with HER2 positive cancer
PurposeThe CellSearch® system has been used to identify circulating tumor cells (CTCs) in cerebrospinal fluid (CSF) to diagnose leptomeningeal...
-
Circulating tumour cells for early detection of clinically relevant cancer
Given that cancer mortality is usually a result of late diagnosis, efforts in the field of early detection are paramount to reducing cancer-related...
