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Could Repeated Cardio-Renal Injury Trigger Late Cardiovascular Sequelae in Extreme Endurance Athletes?
Regular exercise confers multifaceted and well-established health benefits. Yet, transient and asymptomatic increases in markers of cardio-renal...
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Syndromes of Concurrent Hypertension, Diastolic Dysfunction, and Pulmonary or Peripheral Edema in Cardio-Oncology: Case Studies, Literature Review, and New Classification System
Individuals who have ever been diagnosed with cancer are at increased risk for cardiovascular conditions during and after cancer treatment....
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Fenfluramine in clinical practice: new therapy option for Dravet and Lennox–Gastaut syndromes
Fenfluramine is an antiseizure medication for the treatment of Dravet and Lennox–Gastaut syndromes. This review summarizes the literature on the...
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The role of geriatric syndromes in predicting unplanned hospitalizations: a population-based study using Minimum Data Set for Home Care
BackgroundThe predictive accuracies of screening instruments for identifying home-dwelling old people at risk of hospitalization have ranged from...
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Outcomes after stenting of renal artery stenosis in patients with high-risk clinical features
BackgroundIn patients with renal artery stenosis, revascularization was seen as a mean to improve outcomes, but large studies failed to show...
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A new classification of cardio-oncology syndromes
Increasing evidence suggests a multifaceted relationship exists between cancer and cardiovascular disease (CVD). Here, we introduce a 5-tier...
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An Update on the Role of Cardiac Magnetic Resonance Imaging in Cancer Patients
Purpose of ReviewCardiac magnetic resonance imaging has a significant and expanding role to play in contemporary cardio-oncology. This review seeks...
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Specificity of severe AKI aetiology and care in the elderly. The IRACIBLE prospective cohort study
IntroductionAcute Kidney Injury (AKI) is increasingly common in people over 65 years of age, but its causes and management are poorly described. The...
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Rationale and design of an investigator-initiated, multicenter, prospective, placebo-controlled, double-blind, randomized trial to evaluate the effects of finerenone on vascular stiffness and cardiorenal biomarkers in type 2 diabetes and chronic kidney disease (FIVE-STAR)
BackgroundThe overactivation of mineralocorticoid receptor (MR) plays a key pathological role in the progression of cardiovascular and renal diseases...
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Evaluation of ventricular systolic dysfunction as a risk factor for acute kidney injury in intensive care unit
BackgroundHeart failure (HF) is a major health problem. Cardiac and renal diseases interact in a complex bidirectional manner in both acute and...
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Managing heart failure in dialysis patients
The heart and the kidney are intimately connected. They communicate in a bidirectional manner through a variety of pathways, forming an...
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Experiences in Tube Weaning Children with Congenital Heart Disease and Oral Feeding Aversion
Infants and children with congenital heart disease (CHD) often require supplemental nutrition via tube feeding before and after surgery. Tube feeding...
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Pharmacotherapy for Coronary Artery Disease and Acute Coronary Syndrome in the Aging Population
Purpose of ReviewTo provide a comprehensive summary of relevant studies and evidence concerning the utilization of different pharmacotherapeutic and...
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Extending the ‘host response’ paradigm from sepsis to cardiogenic shock: evidence, limitations and opportunities
Recent clinical and research efforts in cardiogenic shock (CS) have largely focussed on the restoration of the low cardiac output state that is the con...
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Impact of Residual Lesion Severity on Neurodevelopmental Outcomes Following Congenital Heart Surgery in Infancy and Childhood
Children with congenital heart disease are at increased risk of neurodevelopmental delay throughout their lifespan. This risk is exacerbated...
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Considering Adverse Effects of Common Antihypertensive Medications in the ED
Purpose of ReviewTo evaluate the adverse effects of common antihypertensive agents utilized or encountered in the Emergency Department.
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Appraisal of guidelines for managing contrast medium in patients with metformin: consensuses, controversies, and gaps
ObjectivesThe current guidelines contain substantial inconsistency regarding the use of metformin concomitantly with contrast media. The objective of...
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Contemporary Management of Cardiomyopathy and Heart Failure in Pregnancy
Cardiovascular disease is the primary cause of pregnancy-related mortality and morbidity in the United States, and maternal mortality has increased...
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Chinese SLE Treatment and Research Group Registry (CSTAR) XIII: prevalence and risk factors for chronic scarring alopecia in patients with systemic lupus erythematosus
BackgroundScarring alopecia in systemic lupus erythematosus (SLE) patients caused reduced life quality and prolonged disease course. This...
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The impact of renal artery stenting on therapeutic aims
Renal artery stenosis manifests as poorly-controlled hypertension, impaired renal function or pulmonary oedema, therefore the success of treatment is...