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Inflammation and Myocardial Blood Flow in Cardiac Sarcoidosis
Purpose of the ReviewCardiac involvement in systemic sarcoidosis or isolated cardiac sarcoidosis plays a pivotal role in the clinical manifestation...
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Inflammation across the spectrum of hypertrophic cardiac phenotypes
The hypertrophic cardiomyopathy phenotype encompasses a heterogeneous spectrum of genetic and acquired diseases characterized by the presence of left...
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Cardiac fibroblast GSK-3α aggravates ischemic cardiac injury by promoting fibrosis, inflammation, and impairing angiogenesis
Myocardial infarction (MI) is the leading cause of death worldwide. Glycogen synthase kinase-3 (GSK-3) has been considered to be a promising...
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LncRNA Gm15834 Aggravates Cardiac Hypertrophy by Interacting with Sam68 and Activating NF-κB Mediated Inflammation
BackgroundCardiac hypertrophy is the common pathological process of multiple cardiovascular diseases. However, the molecular mechanisms of cardiac...
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SARS-CoV-2, vaccination or autoimmunity as causes of cardiac inflammation. Which form prevails?
The causes of cardiac inflammation during the COVID-19 pandemic are manifold and complex, and may have changed with different virus variants and...
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The Role of Serum Monocytes and Tissue Macrophages in Driving Left Ventricular Systolic Dysfunction and Cardiac Inflammation Following Subarachnoid Hemorrhage
BackgroundNeurocardiogenic injury is common after aneurysmal subarachnoid hemorrhage (aSAH) despite low prevalence of preexisting cardiac disease....
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Cardiac deceleration capacity is associated with severity of inflammation in COVID-19
PurposeIn this pilot study, we investigated the cardiac autonomic activity of coronavirus disease 2019 (COVID-19)-infected hospitalized patients....
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Multiparametric cardiac magnetic resonance reveals persistent myocardial inflammation in patients with exertional heat illness
ObjectivesTo explore the clinical potential of multiparametric cardiac magnetic resonance (CMR) in evaluating myocardial inflammation in patients...
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MCT4-dependent lactate transport: a novel mechanism for cardiac energy metabolism injury and inflammation in type 2 diabetes mellitus
Diabetic cardiomyopathy (DCM) is a major contributor to mortality in diabetic patients, characterized by a multifaceted pathogenesis and limited...
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Sex-specific differences in cardiac function, inflammation and injury during early polymicrobial sepsis
BackgroundSex differences in sepsis are underexplored and incompletely understood. Cardiac function in early sepsis is pivotal in determining...
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Genetic Engineering of Donor Pig for the First Human Cardiac Xenotransplantation: Combatting Rejection, Coagulopathy, Inflammation, and Excessive Growth
Purpose of ReviewThe first successful pig to human cardiac xenotransplantation in January 2022 represented a major step forward in the fields of...
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Left Atrial Strain in Multisystem Inflammatory Syndrome in Children and Associations with Systemic Inflammation and Cardiac Injury
Multisystem inflammatory syndrome in children (MIS-C) commonly involves cardiac injury with both systolic and diastolic dysfunction. Left atrial...
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Potential novel imaging targets of inflammation in cardiac sarcoidosis
Cardiac sarcoidosis (CS) is an inflammatory disease with high morbidity and mortality, with a pathognomonic feature of non-caseating granulomatous...
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Cardiac Magnetic Resonance for Myocardial Inflammation: Current State and Future Directions
Purpose of ReviewThis paper summarizes the evolution of cardiac magnetic resonance for the diagnosis of myocarditis and the evidence supporting its...
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Role of Cardiac MRI Imaging of Focal and Diffuse Inflammation and Fibrosis in Cardiomyopathy Patients Who Have Pacemakers/ICD Devices
Purpose of ReviewThis focused report aims to discuss and summarize the use of conventional and emerging methods using cardiovascular magnetic...
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Imaging in Cardiac Sarcoidosis: Complementary Role of Cardiac Magnetic Resonance and Cardiac Positron Emission Tomography
Purpose of ReviewThe purpose of this paper is to review the current role and future directions for cardiac magnetic resonance (CMR) and positron...
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Association of circulating MtDNA with CVD in hemodialysis patients and in vitro effect of exogenous MtDNA on cardiac microvascular inflammation
BackgroundChronic kidney disease (CKD) patients sustain a fairly high prevalence of cardiovascular disease (CVD). Microvascular inflammation is an...
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Santalum album L. alleviates cardiac function injury in heart failure by synergistically inhibiting inflammation, oxidative stress and apoptosis through multiple components
BackgroundHeart failure (HF) is a complex cardiovascular syndrome with high mortality. Santalum album L. (SAL) is a traditional Chinese medicine...
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Fabry Disease: Cardiac Implications and Molecular Mechanisms
Purpose of ReviewThis review explores the interplay among metabolic dysfunction, oxidative stress, inflammation, and fibrosis in Fabry disease,...