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Tissue engineered decellularized bovine pericardium as prosthetic material in paediatric cardiac surgery
AimTo evaluate the short-term outcomes of Tissue Engineered Decellularized Bovine pericardium (Synkroscaff®) in congenital heart surgery as a...
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Role of Cardiac Fibroblasts in Cardiac Injury and Repair
Purpose of ReviewThe pathological remodeling of cardiac tissue after injury or disease leads to scar formation. Our knowledge of the role of...
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Cardiac electrical abnormalities in childhood acute lymphoblastic leukemia survivors: a systematic review
PurposeThe aim was to provide evidence about the prevalence, incidence, and risk factors of cardiac electrical abnormalities in childhood acute...
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The microtubule cytoskeleton in cardiac mechanics and heart failure
The microtubule network of cardiac muscle cells has unique architectural and biophysical features to accommodate the demands of the working heart....
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Metabolic Syndrome and Cardiac Remodeling Due to Mitochondrial Oxidative Stress Involving Gliflozins and Sirtuins
Purpose of ReviewTo address the mechanistic pathways focusing on mitochondria dysfunction, oxidative stress, sirtuins imbalance, and other...
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Distinct cytoskeletal regulators of mechanical memory in cardiac fibroblasts and cardiomyocytes
Recognizing that cells “feel” and respond to their mechanical environment, recent studies demonstrate that many cells exhibit a phenomenon of...
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Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential
Left ventricular hypertrophy is a leading risk factor for cardiovascular morbidity and mortality. Although reverse ventricular remodelling was long...
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The influence of renal disease on outcomes and cardiac remodeling following surgical mitral valve replacement
ObjectivesChronic kidney disease (CKD) is increasingly prevalent in patients undergoing mitral valve replacement (MVR). While CKD is known to result...
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The role of cardiac pericytes in health and disease: therapeutic targets for myocardial infarction
Millions of cardiomyocytes die immediately after myocardial infarction, regardless of whether the culprit coronary artery undergoes prompt...
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A cardioimmunologist’s toolkit: genetic tools to dissect immune cells in cardiac disease
Cardioimmunology is a field that encompasses the immune cells and pathways that modulate cardiac function in homeostasis and regulate the temporal...
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Longitudinal Observational Study of Cardiac Outcome Risk Factor Prediction in Children, Adolescents, and Adults with Barth Syndrome
Barth Syndrome (BTHS) is an X-linked mitochondrial cardioskeletal myopathy caused by defects in TAFAZZIN , a gene responsible for cardiolipin...
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Equine pericardium: a versatile alternative reconstructive material in congenital cardiac surgery
BackgroundPericardial patches are often used for repair of congenital cardiac defects. The aim of this study was to describe our initial experience...
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Left atrial and ventricular longitudinal strain by cardiac magnetic resonance feature tracking improves prognostic stratification of patients with ST-segment elevation myocardial infarction
We aimed to investigate the predictive value of left atrium (LA) and left ventricle (LV) longitudinal strain derived by CMR-FT early after ST-segment...
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Cardiac Regeneration: the Heart of the Issue
Purpose of ReviewThe regenerative capacity of the heart is insufficient to compensate for the pathological loss of cardiomyocytes during a large...
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Reverse Cardiac Remodeling and ARNI Therapy
Purpose of ReviewTo review reverse cardiac remodeling and guideline-directed medical and device therapy (GDMT) within the context of recent data on...
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The role of MRI-R2* in the detection of subclinical pancreatic iron loading among transfusion-dependent sickle cell disease patients and correlation with hepatic and cardiac iron loading
ObjectivesPancreatic reserve could be preserved by early assessment of pancreatic iron overload among transfusion-dependent sickle cell disease (SCD)...
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Cardiac geometry, function and mechanics in left ventricular non-compaction cardiomyopathy with preserved ejection fraction
BackgroundLeft ventricular non-compaction (LVNC) cardiomyopathy in adults has primarily been studied with a phenotypic expression of low ejection...
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Moderately trained male football players, compared to sedentary male adults, exhibit anatomical but not functional cardiac remodelling, a cross-sectional study
BackgroundElite athletes have been the subject of great interest, but athletes at an intermediate level of physical activity have received less...