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Neoadjuvant Immunotherapy for Head and Neck Squamous Cell Carcinoma: Expecting Its Application in Temporal Bone Squamous Cell Carcinoma
Temporal bone malignant tumors are characterized by atypical clinical symptoms, and easy recurrence and metastasis. They account for 0.2% of head and...
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Radioresistance or/and radiosensitivity of head and neck squamous cell carcinoma: biological angle
ObjectiveThis narrative review aimed to compile and summarize clinically relevant literature in radiation therapy and to discuss the potential in...
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Primary Oropharyngeal SMARCA4-Deficient Carcinoma: Expanding the Diagnostic Spectrum in Head and Neck Cancer
With the advent of molecular immunohistochemistry and next generation sequencing, Switch/sucrose non-fermentable (SWI/SNF) chromatin remodeling...
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Comparative Evaluation of Surgical Operability with and without Induction Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma
To compare and evaluation of surgical operability with and without induction chemotherapy in locally advanced head and neck squamous cell carcinoma....
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Predictive value of tumor budding in head and neck squamous cell carcinoma: an update
Head and neck squamous cell carcinoma forms an anatomically and functionally complex group of malignancies. The significant local aggressiveness and...
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Head and neck mucoepidermoid carcinoma: does AFIP histological grading correlate with rate of nodal metastases?
ObjectiveThe aim of this study is to retrospectively evaluate the presentation of head and neck mucoepidermoid carcinoma at the Royal Melbourne...
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Assessing PD-L1 Expression in Head and Neck Squamous Cell Carcinoma: Trials and Tribulations
Immune checkpoint inhibitors have improved the outcome of patients diagnosed with inoperable recurrent or metastatic head and neck squamous cell...
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Head and neck malignant lymphoma and squamous cell carcinoma discernment, is DWI conclusive?
BackgroundDifferentiation between head-and-neck malignant lymphoma and squamous cell carcinoma is crucial as their management is radically different,...
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Head and neck INI1-deficient carcinoma without primary: a case report
BackgroundSMARCB1, also known as INI1, is a member of a large protein complex involved in chromatin remodeling and thus the regulation of gene...
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Results of salvage neck dissection after chemoradiation in locally advanced head and neck squamous cell carcinoma
PurposeSalvage surgery is mandatory when regional persistence/recurrence after chemoradiation. The aim of this study is to describe the outcomes of...
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Induction Therapy for Locally Advanced Head and Neck Squamous Cell Carcinoma
The optimal approach to locally advanced head and neck squamous cell carcinoma (LAHNSCC) treatment remains controversial. For non-resectable LAHNSCC,...
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Granulation tissue-like spindle cell (sarcomatoid) carcinoma of the head and neck: a deceptively bland-looking underdiagnosed malignancy
The diagnosis of head and neck spindle cell squamous carcinoma (SC-SCC) is often challenging. Lesions with a prominent inflammatory infiltrate and...
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Exploring the frontiers: tumor immune microenvironment and immunotherapy in head and neck squamous cell carcinoma
The global prevalence of head and neck malignancies positions them as the sixth most common form of cancer, with the head and neck squamous cell...
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The Current Management of Merkel Carcinoma of the Head and Neck: a Sco** Review
Merkel cell carcinoma (MCC) is an aggressive neuroendocrine cutaneous malignancy, most commonly occurring in the head and neck region. Given the...
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Kruppel-family zinc finger proteins as emerging epigenetic biomarkers in head and neck squamous cell carcinoma
BackgroundKrüppel-type zinc finger protein genes located on chromosome 19q13 are aberrantly hypermethylated with high frequency in all anatomic...
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Dual-energy computed tomography for improved visualization of internal jugular chain neck lymph node metastasis and nodal necrosis in head and neck squamous cell carcinoma
PurposeTo evaluate and compare the utility of 40-keV virtual monochromatic imaging (VMI) reconstructed from dual-energy computed tomography (DECT) in...
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Basaloid squamous cell carcinoma clinically and radiologically masquerading as a head and neck paraganglioma: a case report and review of the literature
BackgroundThis paper reports the first case of basaloid squamous cell carcinoma clinically and radiologically masquerading as a head and neck...
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A Prospective Study Between Molecular Marker P53 Analysis and HPE, for Tumour Positivity in Primary Resected Margins in Head and Neck Squamous Cell Carcinoma
Head and neck malignancies are the seventeenth most common malignancies, worldwide and second most common malignancy in India. So current study aims...
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Genetically engineered mouse models of head and neck cancers
The head and neck region is one of the anatomic sites commonly afflicted by cancer, with ~1.5 million new diagnoses reported worldwide in 2020 alone....
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Pretreatment pain predicts perineural invasion in patients with head and neck squamous cell carcinoma
ObjectivesPerineural invasion (PNI) in head and neck cancer (HNC) is a distinct pathological feature used to indicate aggressive tumor behavior and...
