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Preparation of anti-canine interleukin-31 receptor alpha polyclonal antibody and evaluation of its therapeutic effect in canine atopic dermatitis
Canine atopic dermatitis (CAD) is a prevalent genetically susceptible inflammatory and pruritic allergic skin condition affecting not only the health...
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Fusion protein and hemagglutinin of canine distemper virus co-induce apoptosis in canine mammary tumor cells
BackgroundCanine distemper virus (CDV) has been shown to have oncolytic activity against primary canine tumors. Previous studies from this laboratory...
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Establishment and characterization of a canine chondrosarcoma cell line: Mango
In the global progress of bone tumor research, established stable and long-lasting transgenic chondrosarcoma (CSA) cell lines are rare, mainly of...
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Diagnostic value of procalcitonin, C-reactive protein, and leukocyte count in canine ehrlichiosis and canine demodicosis
Canine ehrlichiosis ( E. canis ) is an obligate intracellular organism that resides as a microcolony within a membrane-lined intracellular vacuole...
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COVID-19 restrictions limit the circulation of H3N2 canine influenza virus in China
Canine health is consistently affected by the circulation of the H3N2 strain of canine influenza virus (CIV). Prior research has indicated that the...
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Targeting osteosarcoma with canine B7-H3 CAR T cells and impact of CXCR2 Co-expression on functional activity
The use of large animal spontaneous models of solid cancers, such as dogs with osteosarcoma (OS), can help develop new cancer immunotherapy...
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Re-evaluating the placebo response in recent canine dietary epilepsy trials
The placebo response is a common phenomenon. Limited evidence is available about its magnitude in canine epilepsy trials, even though it can...
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Usability of serum hedgehog signalling proteins as biomarkers in canine mammary carcinomas
BackgroundThe hedgehog signalling pathway has been implicated in tumourigenesis and progression of many tumour types. This pathway has recently...
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Upregulation of SLUG expression in canine mammary gland tumors and its prognostic significance
BackgroundSLUG (also known as snai2), which is a transcription factor in epithelial–mesenchymal transition (EMT), plays an important role in...
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Establishment of canine mammary gland tumor cell lines harboring PI3K/Akt activation as a therapeutic target
Canine mammary gland tumors (MGT) have a poor prognosis in intact female canines, posing a clinical challenge. This study aimed to establish novel...
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Canine ocular thelaziosis: first report in Andhra Pradesh
Thelaziosis is a vector-borne zoonotic disease with worldwide distribution, including in India and reports on canine ocular thelaziosis are very...
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Develo** diagnostic tools for canine periodontitis: combining molecular techniques and machine learning models
BackgroundDental plaque microbes play a key role in the development of periodontal disease. Numerous high-throughput sequencing studies have...
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Retrospective study of acupuncture treatment for canine thoracolumbar intervertebral disc herniation
Thoracolumbar interverbal disk herniation (TL-IVDH) is a common neurological disorder in dogs, which often affects the life quality of patients and...
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Canine ehrlichiosis seropositivity and associated factors in Kenya and Tanzania: a retrospective study
Canine ehrlichiosis is an important tick-borne disease caused by bacteria in the Ehrlichia genus with species such as E. canis, E. ewingii and E. chaffeensis...
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Deciphering Stromal Changes between Metastatic and Non-metastatic Canine Mammary Carcinomas
Cancer-associated stroma (CAS) is widely recognized to influence development and progression of epithelial tumours including breast cancer. Canine...
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Hemolysis, icterus and lipemia interfere with the determination of two oxidative stress biomarkers in canine serum
BackgroundOxidative stress has been proven to play a role in numerous human and canine diseases. Among the biomarkers of oxidative stress,...
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Dose-dependent effect of canine lyophilized platelet on an in vitro hemodilution model
The transfusion of stored platelets has emerged as an efficient method for treating dogs with thrombocytopenia. However, the availability of fresh...
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Comparison of the recovery characteristics for canine corneal ulcer treated with corneoconjunctival transposition or conjunctival autografts
Corneal ulceration induced by Staphylococcus pseudintermedius ( S. pseudintermedius ) is a common clinical eye disease. Antibiotics combined with...
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Evaluation of canine adipose-derived mesenchymal stem cells for neurological functional recovery in a rat model of traumatic brain injury
BackgroundTraumatic brain injury (TBI) is a common condition in veterinary medicine that is difficult to manage.Veterinary regenerative therapy based...
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Establishment and characterization of a HER2-enriched canine mammary cancerous myoepithelial cell line
BackgroundCanine mammary tumors (CMTs) have a poor prognosis, along with tumor recurrence and metastasis. Cell lines are vital in vitro models for...
