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Identification of ferroptosis related genes and pathways in prostate cancer cells under erastin exposure
BackgroundFew studies are focusing on the mechanism of erastin acts on prostate cancer (PCa) cells, and essential ferroptosis-related genes (FRGs)...
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Photodynamic therapy upregulates expression of HIF-1α and PD-L1 in related pathways and its clinical relevance in non-small-cell lung cancer
BackgroundPhotodynamic therapy (PDT) is a promising interventional treatment approach that contributes to antitumor immunity. It has been reported...
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Identification of key genes and pathways related to cancer-associated fibroblasts in chemoresistance of ovarian cancer cells based on GEO and TCGA databases
BackgroundStudies have revealed the implications of cancer-associated fibroblasts (CAFs) in tumor progression, metastasis, and treatment resistance....
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The role of the inflammasome and its related pathways in ovarian cancer
Ovarian cancer (OC) is the most lethal tumor of the female reproductive tract and one of the most prevalent causes of death among female cancer...
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Relevance of Cardiovascular Exercise in Cancer and Cancer Therapy-Related Cardiac Dysfunction
Purpose of the ReviewCancer therapy-related cardiac dysfunction (CTRCD) has been identified as a threat to overall and cancer-related survival....
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Systematic identification of the cancer pathways and molecules related with breast cancer immunogenicity
To identify molecular features related to immunogenic activity in breast cancer (BC) and provide new targets and directions for BC immunotherapy, we...
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The influence of selected microRNAs on the expression profile of genes and proteins related to the tumor necrosis factor-alpha signaling pathways in endometrioid endometrial cancer
PurposeTumor necrosis factor exerts many adverse biological effects, from cell proliferation to cell death. Accurate diagnosis and treatment are...
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Comprehensive analyses of mitophagy-related genes and mitophagy-related lncRNAs for patients with ovarian cancer
BackgroundBoth mitophagy and long non-coding RNAs (lncRNAs) play crucial roles in ovarian cancer (OC). We sought to explore the characteristics of...
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Construction and Validation of a Seven Anoikis-Related lncRNA Risk Model for Breast Cancer
The current understanding of breast cancer (BC) progression and prognosis related to Anoikis-associated long noncoding RNAs (lncRNAs) is limited. The...
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Innovative molecular subtypes of multiple signaling pathways in colon cancer and validation of FMOD as a prognostic-related marker
PurposeColon cancer is highly heterogeneous in terms of the immune and stromal microenvironment, genomic integrity, and oncogenic properties;...
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An immune-related exosome signature predicts the prognosis and immunotherapy response in ovarian cancer
BackgroundCancer-derived exosomes contribute significantly in intracellular communication, particularly during tumorigenesis. Here, we aimed to...
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Germline determinants of aberrant signaling pathways in cancer
Cancer is a complex disease influenced by a heterogeneous landscape of both germline genetic variants and somatic aberrations. While there is growing...
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Biological mechanisms of cancer-related fatigue in breast cancer survivors after treatment: a sco** review
PurposeCancer-related fatigue (CRF) is the most common symptom experienced by cancer survivors. It is a multidimensional symptom affecting physical,...
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Prognostic and immune infiltration features of disulfidptosis-related subtypes in breast cancer
Breast cancer (BC) is a prominent cause of cancer incidence and mortality around the world. Disulfidptosis, a type of cell death, can induce tumor...
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Pan-cancer analyses of senescence-related genes in extracellular matrix characterization in cancer
PurposeThe aged microenvironment plays a crucial role in tumor onset and progression. However, it remains unclear whether and how the aging of the...
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Potential mechanisms underlying the effect of walking exercise on cancer-related fatigue in cancer survivors
PurposeCancer-related fatigue (CRF) is a common and debilitating long-term side effect of cancer and its treatment. While exercise has been shown to...
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Cuproptosis-related gene SERPINE1 is a prognostic biomarker and correlated with immune infiltrates in gastric cancer
PurposeThe serine protease inhibitor clade E member 1 (SERPINE1) has been studied as a potential biomarker in a variety of cancers, but poorly...
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Metabolic pathways in obesity-related breast cancer
This Review focuses on the mechanistic evidence for a link between obesity, dysregulated cellular metabolism and breast cancer. Strong evidence now...
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Prognostic significance and immune landscape of a cell cycle progression-related risk model in bladder cancer
BackgroundA greater emphasis has been placed on the part of cell cycle progression (CCP) in cancer in recent years. Nevertheless, the precise...
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Risk assessment model based on nucleotide metabolism-related genes highlights SLC27A2 as a potential therapeutic target in breast cancer
PurposeBreast cancer (BC) is the most prevalent malignant tumor worldwide among women, with the highest incidence rate. The mechanisms underlying...
