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Diagnosestellung eines „cancer of unknown primary“
BackgroundWith an incidence of 1–3% of all malignancies, cancer of unknown primary (CUP) remains a relevant tumor entity. It is defined by...
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Radiologische Bildgebung bei „cancer of unknown primary“
ProblemIf no obvious primary tumor is detectable in metastatic tumors (cancer of unknown primary, CUP), it should nevertheless be identified if...
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Cancer of unknown primary—state of the art
The Cancer of Unknown Primary (CUP) syndrome does not represent a single clinical entity but comprises a diverse group of malignant tumors. CUP is...
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„Cancer of unknown primary“ – Stellenwert der Chirurgie
BackgroundDue to the numerous subgroups and relatively low incidence rate, cancer of unknown primary (CUP) presents an imposing challenge in both...
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„Breast-like cancer of unknown primary“
BackgroundCancer of unknown primary (CUP) is defined by the presence of metastatic disease with an undetectable primary tumor at the time of...
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Cancer of unknown primary eventually diagnosed as poorly differentiated prostate cancer: a case report
BackgroundProstate cancer has been well known to have a high prevalence among middle-aged and older men, with high incidence of metastases to the...
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„Cancer of unknown primary“ – histologische und molekularpathologische Grundlagen in der Diagnostik
Cancer of unknown primary (CUP) requires multimodal diagnostics that include all specialist disciplines involved. Given the challenging diagnosis,...
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„Cancer of unknown primary origin“ – Stellenwert der Strahlentherapie in der multimodalen Behandlung
BackgroundTreatment of cancer of unknown primary (CUP) remains challenging in terms of pretreatment diagnostics and therapeutic algorithms. Depending...
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PD-L1 expression and microsatellite instability (MSI) in cancer of unknown primary site
BackgroundCancer of unknown primary site (CUP) is a heterogeneous group of tumors for which the origin remains unknown. Clinical outcomes might be...
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Clinical outcomes of patients diagnosed with cancer of unknown primary or malignancy of undefined primary origin who were referred to a regional cancer center
BackgroundA regional cancer hospital has been identified to be crucial in the management of malignancies of undefined primary origin (MUO) and cancer...
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Bone metastatic cancer of unknown primary at initial presentation
IntroductionCancer of unknown primary (CUP) is a challenging malignancy. The purpose of this study was to investigate the clinical characteristics...
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A case of hereditary breast and ovarian cancer syndrome of initially presented as cancer of unknown primary with lymph node metastases unveiled by genetic analysis
Cancer of unknown primary (CUP) is a heterogeneous disease concept involving various malignant tumors. Understanding its pathophysiology is often...
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The practical utility of AI-assisted molecular profiling in the diagnosis and management of cancer of unknown primary: an updated review
Cancer of unknown primary (CUP) presents a complex diagnostic challenge, characterized by metastatic tumors of unknown tissue origin and a dismal...
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Healthcare Costs Before and After Diagnosis of Cancer of Unknown Primary Versus Ovarian Cancer in Australia
BackgroundLittle is known about the healthcare resource usage and costs for patients with cancer of unknown primary (CUP).
ObjectiveThe aim of this...
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Cancer of unknown primary (CUP) – lokal begrenzt, oligometastatisch und im Kopf-Hals-Bereich
IntroductionAbout 20% of all cancer of unknown primary (CUP) cases can be classified into favorable subgroups, which are defined by either obvious...
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Cancer of unknown primary (CUP) through the lens of precision oncology: a single institution perspective
PurposeFor patients with cancer of unknown primary (CUP), treatment options are limited. Precision oncology, the interplay of comprehensive genomic...
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Biomarkers in Carcinoma of Unknown Primary
This book aims to examine all immunohistochemical and molecular pathological biomarkers that can be useful and effective in patient diagnosis,...
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Significance of Distinct Liquid Biopsy Compartments in Evaluating Somatic Mutations for Targeted Therapy Selection in Cancer of Unknown Primary
PurposeCancer of unknown primary (CUP) accounts for 2–5% of all cancer diagnoses, wherein standard investigations fail to reveal the original tumor...
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Comparison of PD-L1 expression in squamous cell cancer of unknown primary and oropharyngeal squamous cell carcinoma
PurposeThe tumorigenesis of squamous cell cancer of unknown primary (SCCUP) in the head and neck area has not been decoded so far, while poor...
