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1. Medical imaging in cancer cachexia

   Cancer cachexia, often referred to as “wasting syndrome,” is characterized by fatigue, weakness, and involuntary weight loss. This syndrome is...

   Hyun Soo Ko, Ulrike Attenberger in Die Radiologie

   Article Open access 12 July 2024
   

2. Relationships of emerging biomarkers of cancer cachexia with quality of life, appetite, and cachexia

   Purpose

   Quality of life (QoL), appetite, cachexia, and biomarkers [albumin, hemoglobin (Hb), neutrophils, lymphocytes, platelets, C-reactive protein...

   M. Lipshitz, J. Visser, ... BL. Rapoport in Supportive Care in Cancer

   Article Open access 14 May 2024
   

3. Factors associated with multimodal care practices for cancer cachexia among registered dietitians

   Purpose

   This study aimed to determine factors associated with multimodal care practices for cancer cachexia among registered dietitians (RDs) working...

   Koji Amano, Saori Koshimoto, ... Naoharu Mori in Supportive Care in Cancer

   Article 06 March 2024

4. Cancer cachexia: molecular mechanisms and treatment strategies

   Muscle wasting is a consequence of physiological changes or a pathology characterized by increased catabolic activity that leads to progressive loss...

   Tania Setiawan, Ita Novita Sari, ... Hyog Young Kwon in Journal of Hematology & Oncology

   Article Open access 22 May 2023
   

5. Effect of cancer cachexia on first-line chemotherapy in patients with advanced pancreatic cancer: a claims database study in Japan

   Background

   Cancer cachexia is a multifactorial syndrome leading to progressive functional impairment. How cachexia affects the treatment course of...

   Junji Furuse, Fumihiko Osugi, ... Toshimitsu Endo in International Journal of Clinical Oncology

   Article Open access 14 February 2024
   

6. SEOM clinical guidelines for cancer anorexia-cachexia syndrome (2023)

   Cancer-related anorexia-cachexia syndrome (CACS) is a debilitating condition afflicting up to 80% of advanced-stage cancer patients. Characterized by...

   Ainara Soria Rivas, Yolanda Escobar Álvarez, ... Luis Cabezón Gutierrez in Clinical and Translational Oncology

   Article Open access 01 June 2024
   

7. The roles of P-selectin in cancer cachexia

   P -selectin, a cell adhesion molecule of the selectin family, is expressed on the surface of activated endothelial cells (ECs) and platelets. Binding...

   Tingting Ling, **g Liu, ... Ju Liu in Medical Oncology

   Article 23 October 2023
   

8. Emerging markers of cancer cachexia and their relationship to sarcopenia

   Purpose

   Emerging biomarkers of cancer cachexia and their roles in sarcopenia and prognosis are poorly understood. Baseline assessments of...

   Melanie Lipshitz, J. Visser, ... B. Rapoport in Journal of Cancer Research and Clinical Oncology

   Article Open access 31 October 2023
   

9. Cachexia Index in Patients with Gastrointestinal Cancer: A Systematic Review and Meta-Analysis

   Purpose

   The cachexia index is a novel biomarker of cancer cachexia. This systematic review and meta-analysis aimed to evaluate the prognostic impact...

   Yasuhiro Takano, Wataru Kai, ... Nobuyoshi Hanyu in Journal of Gastrointestinal Cancer

   Article 27 April 2024
   

10. The cachexia index is a prognostic factor for patients with recurrent pancreatic cancer

    Purpose

    Cancer cachexia leads to poor outcomes, especially for patients with advanced stage disease. The cachexia index (CXI), a novel biomarker for...

    Teruhisa Sakamoto, Mikiya Kishino, ... Yoshiyuki Fujiwara in Surgery Today

    Article 01 June 2024
    

11. Malnutrition, sarcopenia and cachexia: exploring prevalence, overlap, and perceptions in older adults with cancer

    Background

    Older adults with cancer are a growing population requiring tailored care to achieve optimum treatment outcomes. Their care is complicated...

    Alex F. Bullock, Michael J. Patterson, ... Miriam J. Johnson in European Journal of Clinical Nutrition

    Article Open access 05 April 2024
    

12. Association of a newly developed Cancer Cachexia Score with survival in Stage I–III colorectal cancer

    Purpose

    Cancer cachexia, a complex multifactorial syndrome associated with sarcopenia, negatively affects the quality of life and survival in patients...

    Yasuhiro Takano, Keita Kodera, ... Ken Eto in Langenbeck's Archives of Surgery

    Article 12 April 2023
    

13. Cancer-associated cachexia — understanding the tumour macroenvironment and microenvironment to improve management

    Cachexia is a devastating, multifactorial and often irreversible systemic syndrome characterized by substantial weight loss (mainly of skeletal...

    Josep M. Argilés, Francisco J. López-Soriano, ... Silvia Busquets in Nature Reviews Clinical Oncology

    Article 20 February 2023
    

14. Anamorelin for the Treatment of Cancer Anorexia-Cachexia Syndrome

    Purpose of Review

    The following review will highlight the development of anamorelin to treat cancer anorexia-cachexia syndrome (CACS) including the...

    Rony Dev, Koji Amano, ... Egidio Del Fabbro in Current Oncology Reports

    Article 21 May 2024
    

15. Factors associated with early discontinuation of anamorelin in patients with cancer-associated cachexia

    Purpose

    Cancer-associated cachexia, a multifactorial syndrome involving loss of muscle mass and anorexia, is an unremitting problem for cancer...

    Ikuto Tsukiyama, Takashi Iwata, ... Naoharu Mori in Supportive Care in Cancer

    Article Open access 10 October 2023
    

16. Understanding Cancer Cachexia and Its Implications in Upper Gastrointestinal Cancers

    Considerable advances in the investigation and management of oesophagogastric cancer have occurred over the last few decades. While the historically...

    Leo R. Brown, Barry J. A. Laird, ... Richard J. E. Skipworth in Current Treatment Options in Oncology

    Article Open access 21 October 2022
    

17. The weight loss grading system as a predictor of cancer cachexia in oesophageal cancer survivors

    Background

    Oesophageal cancer survivorship is afflicted by cancer cachexia related weight loss and nutrition impact symptoms. Identifying the factors...

    Poorna Anandavadivelan, Asif Johar, Pernilla Lagergren in European Journal of Clinical Nutrition

    Article Open access 18 August 2022
    

18. Significance of localized expression of full-length growth differentiation factor-15 in cachexia of advanced non-small cell lung cancer

    Purpose

    Growth differentiation factor-15 (GDF-15) is one of the key cachexia-inducing factors. Clinical trials on therapies targeting GDF-15 for...

    Satomi Morita-Tanaka, Aya Miyagawa-Hayashino, ... Koichi Takayama in Supportive Care in Cancer

    Article 28 April 2023
    

19. Jianpi Decoction Combined with Medroxyprogesterone Acetate Alleviates Cancer Cachexia and Prevents Muscle Atrophy by Directly Inhibiting E3 Ubiquitin Ligase

    Objective

    To provide comprehensive evidence for the anti-cancer cachexia effect of Jianpi Decoction (JP) and to explore its mechanism of anti-cancer...

    Qi Li, Zhao-di Kong, ... Zhen-jiang Yang in Chinese Journal of Integrative Medicine

    Article 24 August 2023

20. LCN2 secreted by tissue-infiltrating neutrophils induces the ferroptosis and wasting of adipose and muscle tissues in lung cancer cachexia

    Background

    Cancer cachexia is a deadly wasting syndrome that accompanies various diseases (including ~ 50% of cancers). Clinical studies have...

    Dong Wang, **aohui Li, ... Haiming Wei in Journal of Hematology & Oncology

    Article Open access 27 March 2023