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Impact of BMI on serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D with calcifediol supplementation in young adults: a longitudinal study
BackgroundHigh body mass index (BMI) is a risk factor for vitamin D deficiency. The rise in serum 25-hydroxyvitamin D [25(OH)D] concentrations...
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Calcifediol supplementation in adults on hemodialysis: a randomized controlled trial
BackgroundVitamin D deficiency is associated with increased risks of mortality in people with chronic kidney disease. The benefits and harm of...
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Extended-release calcifediol in stage 3–4 chronic kidney disease: a new therapy for the treatment of secondary hyperparathyroidism associated with hypovitaminosis D
A high percentage of patients with chronic kidney disease have hypovitaminosis D, which is a driver of secondary hyperparathyroidism and an important...
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Effect of vitamin D3 vs. calcifediol on VDR concentration and fiber size in skeletal muscle
IntroductionThis study sought to examine the effect of vitamin D 3 (VD 3 ) 3200 IU/d, calcifediol (HyD) 20mcg/d, or placebo on intramyonuclear vitamin...
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Real-world assessment: effectiveness and safety of extended-release calcifediol and other vitamin D therapies for secondary hyperparathyroidism in CKD patients
IntroductionExtended-release calcifediol (ERC), active vitamin D hormones and analogs (AVD) and nutritional vitamin D (NVD) are commonly used...
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Pharmacokinetic profile and effect on bone markers and muscle strength of two daily dosage regimens of calcifediol in osteopenic/osteoporotic postmenopausal women
BackgroundAt present, although cholecalciferol represents the form of vitamin D of choice for the treatment of vitamin D deficiency, there is a...
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Role of vitamin D supplementation in the management of musculoskeletal diseases: update from an European Society of Clinical and Economical Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) working group
Vitamin D is a key component for optimal growth and for calcium–phosphate homeostasis. Skin photosynthesis is the main source of vitamin D. Limited...
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Vitamin D in hypoparathyroidism: insight into pathophysiology and perspectives in clinical practice
Hypoparathyroidism (HypoPT) is a rare endocrine disorder characterized by the absence or insufficient parathyroid hormone production resulting in...
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Vitamin D supplementation and COVID-19 risk: a population-based, cohort study
PurposeTo analyze the associations between cholecalciferol or calcifediol supplementation, serum 25-hydroxyvitamin D (25OHD) levels and COVID-19...
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Vitamin D supplementation: cholecalciferol, calcifediol, and calcitriol
The specific compound that is meant for use in the context of vitamin D supplementation is often ambiguous. The term “supplementation” has been used...
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The effect of macronutrient and micronutrient supplements on COVID-19: an umbrella review
Background and aimsA healthy diet play an important role in the prevention and even treatment of various diseases. Proper nutrition plays an...