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Prenatal diagnosis of a trisomy 7 mosaic case: CMA, CNV-seq, karyoty**, interphase FISH, and MS-MLPA, which technique to choose?
ObjectiveThis study aims to perform a prenatal genetic diagnosis of a high-risk fetus with trisomy 7 identified by noninvasive prenatal testing...
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RPE disruption and hyper-transmission are early signs of secondary CNV with punctate inner choroidopathy in structure-OCT
PurposeTo study whether retinal pigment epithelium (RPE) disruption and choroidal hyper-transmission on spectral-domain optical coherence tomography...
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Establishment of a novel CNV-related prognostic signature predicting prognosis in patients with breast cancer
BackgroundCopy number variation (CNVs) is a key factor in breast cancer development. This study determined prognostic molecular characteristics to...
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Enlargement rate of geographic atrophy before and after secondary CNV conversion with associated anti-VEGF treatment
BackgroundTo study the enlargement rate of primary geographic atrophy (GA) before and after diagnosis of a secondary choroidal neovascularization...
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Die fibrovaskuläre Umwandlung der CNV bei nAMD unter lang andauernder Anti-VEGF-Therapie
BackgroundUnder long-term anti-VEGF therapy neovascular age-related macular degeneration (nAMD) may result in fibrovascular transformation of...
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OCTA evaluation of treatment-naïve flat irregular PED (FIPED)-associated CNV in chronic central serous chorioretinopathy before and after half-dose PDT
BackgroundTo qualitatively and quantitatively evaluate the features of treatment-naïve flat irregular pigment epithelial detachment...
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Einfluss der CNV-Gefäßmorphologie bei exsudativer altersabhängiger Makuladegeneration auf die Visusentwicklung und den Anti-VEGF-Therapiebedarf nach 1 Jahr
BackgroundThe aim of this pilot study was to investigate vascular morphological characteristics of choroidal neovascularization (CNV) at the time of...
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Myopic choroidal neovascularization with neovascular signal around perforating scleral vessel prone to recur after anti-VEGF therapy
BackgroundTo compare the recurrence of myopic choroidal neovascularization (mCNV) based on the neovascular signal of mCNV around the perforating...
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Dynamic changes in macrophage morphology during the progression of choroidal neovascularization in a laser-induced choroidal neovascularization mouse model
BackgroundNeovascular age-related macular degeneration (AMD) is responsible for the majority of severe vision loss cases and is mainly caused by...
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‘Structural OCT changes distinguishing between myopic macular haemorrhages due to choroidal neovascularization and spontaneous Bruch’s membrane rupture: the “myopic 2 binary reflective sign”
ObjectiveTo evaluate the sensitivity and specificity of structural optical coherence tomography (OCT) in comparison to fluorescein angiography (FA)...
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A review of the cognitive impact of neurodevelopmental and neuropsychiatric associated copy number variants
The heritability of intelligence or general cognitive ability is estimated at 41% and 66% in children and adults respectively. Many rare copy number...
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Copy number variation analysis in 138 families with steroid-resistant nephrotic syndrome identifies causal homozygous deletions in PLCE1 and NPHS2 in two families
BackgroundSteroid-resistant nephrotic syndrome (SRNS) is the second most common cause of kidney failure in children and adults under the age of...
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Prognostic factors for intravitreal conbercept in the treatment of choroidal neovascularization secondary to pathological myopia
PurposeTo identify risk factors influencing visual outcomes in patients with pathological myopia-associated choroidal neovascularization (PM-CNV)...
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Correlation between AI-measured lacquer cracks extension and development of myopic choroidal neovascularization
ObjectivesTo investigate the correlation between the AI-measured area of the lacquer cracks (LC) at their first detection and the occurrence of a...
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Persistence of vascular empty sleeves in choroidal neovascularization after VEGF therapy in both animal models and humans
PurposeChoroidal neovascularization (CNV) often recurs during anti-vascular endothelial growth factor (VEGF) therapy; however, little is known about...
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Comparison of anatomical and functional outcomes of treating myopic choroidal neovascularization with bevacizumab or ranibizumab
PurposeTo compare results of treatment with bevacizumab and ranibizumab injections in myopic choroidal neovascularization (mCNV).
Methods ...
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Effect of a protein kinase B (Akt) inhibitor on the angiogenesis of HUVECs and corneal neovascularization
BackgroundCorneal neovascularization (CNV) is a vision-threatening disease and an increasing public health concern. It was found that administering...
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Individual vs. combined imaging modalities for diagnosing neovascular central serous chorioretinopathy
PurposeTo assess the diagnostic accuracy of individual and combined imaging modalities compared with multimodal imaging for the detection of...
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Efficacy and safety of intravitreal injections of conbercept for the treatment of idiopathic choroidal neovascularization
BackgroundTo determine the efficacy and safety of intravitreally injected conbercept, a vascular endothelial growth factor receptor fusion protein,...
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Long-term predictors of anti-VEGF treatment response in patients with neovascularization secondary to CSCR: a longitudinal study
PurposeTo identify the baseline predictors of anti-VEGF treatment response at 3 years in patients affected by choroidal neovascularization (CNV)...
