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Inversion recovery and saturation recovery pulmonary vein MR angiography using an image based navigator fluoro trigger and variable-density 3D cartesian sampling with spiral-like order
Contrast enhanced pulmonary vein magnetic resonance angiography (PV CE-MRA) has value in atrial ablation pre-procedural planning. We aimed to provide...
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Anti-LGI1 encephalitis recurring 3 years after the first episode: a case report
BackgroundPatients with antibodies against leucine-rich glioma-inactivated 1 (LGI1) present with limbic encephalitis, which is clinically...
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Concussion leads to widespread axonal sodium channel loss and disruption of the node of Ranvier
Despite being a major health concern, little is known about the pathophysiological changes that underly concussion. Nonetheless, emerging evidence...
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Sex differences in the extent of acute axonal pathologies after experimental concussion
Although human females appear be at a higher risk of concussion and suffer worse outcomes than males, underlying mechanisms remain unclear. With...
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Minimum effective dose of clemastine in a mouse model of preterm white matter injury
BackgroundPreterm white matter injury (PWMI) is the most common cause of brain injury in premature neonates. PWMI involves a differentiation arrest...
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MERTK in the rat trigeminal system: a potential novel target for cluster headache?
The trigeminal system is key to the pathophysiology of migraine and cluster headache, two primary headache disorders that share many features....
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C-fibers may modulate adjacent Aδ-fibers through axon-axon CGRP signaling at nodes of Ranvier in the trigeminal system
BackgroundMonoclonal antibodies (mAbs) towards CGRP or the CGRP receptor show good prophylactic antimigraine efficacy. However, their site of action...
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Expression of vasopressin and its receptors in migraine-related regions in CNS and the trigeminal system: influence of sex
BackgroundHypothalamus is a key region in migraine attacks. In addition, women are disproportionately affected by migraine. The calcitonin...
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Sleep disorders and polysomnography findings in patients with autoimmune encephalitis
BackgroundSleep disorders in patients with autoimmune encephalitis (AE) are increasingly reported. Early recognition and treatment have significant...
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Node of Ranvier remodeling in chronic psychosocial stress and anxiety
Differential expression of myelin-related genes and changes in myelin thickness have been demonstrated in mice after chronic psychosocial stress, a...
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Altered regulation of oligodendrocytes associated with parvalbumin neurons in the ventral hippocampus underlies fear generalization in male mice
Fear generalization is a neurobiological process by which an organism interprets a novel stimulus as threatening because of its similarity to...
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Long-term outcome in new onset refractory status epilepticus: a retrospective study
BackgroundNew onset refractory status epilepticus (NORSE) is a neurologic emergency without an immediately identifiable cause. The complicated and...
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Lasmiditan and 5-Hydroxytryptamine in the rat trigeminal system; expression, release and interactions with 5-HT1 receptors
Background5-Hydroxytryptamine (5-HT) receptors 1B, 1D and 1F have key roles in migraine pharmacotherapy. Selective agonists targeting these...
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Anti-pan-neurofascin nodopathy: cause of fulminant neuropathy
Autoimmune nodopathies are inflammatory diseases of the peripheral nervous system with clinical and neurophysiological peculiar characteristics. In...
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Parkinson-ALS with a novel MAPT variant
The mutations on microtubule associated protein tau ( MAPT ) gene manifest clinically with behavioural frontotemporal dementia (FTD), parkinsonism,...
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Motion robust coronary MR angiography using zigzag centric ky–kz trajectory and high-resolution deep learning reconstruction
PurposeTo develop a new MR coronary angiography (MRCA) technique by employing a zigzag fan-shaped centric k y – k z k -space trajectory combined with...
