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Analysis of urinary C–C motif chemokine ligand 14 (CCL14) and first-generation urinary biomarkers for predicting renal recovery from acute kidney injury: a prospective exploratory study
BackgroundAcute kidney injury (AKI) is a frequent syndrome in the intensive care unit (ICU). AKI patients with kidney function recovery have better...
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Performance of urinary C–C motif chemokine ligand 14 for the prediction of persistent acute kidney injury: a systematic review and meta-analysis
BackgroundUrinary C–C motif chemokine ligand 14 (CCL14) has been described as an effective marker for delayed recovery of acute kidney injury (AKI),...
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Predictability performance of urinary C–C motif chemokine ligand 14 and renal resistive index for persistent sepsis-associated acute kidney injury in ICU patients
ObjectivesThe performance of renal resistance index (RRI) in predicting persistent sepsis-associated acute kidney injury (S-AKI) remains debatable,...
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External validation of urinary C–C motif chemokine ligand 14 (CCL14) for prediction of persistent acute kidney injury
BackgroundPersistent acute kidney injury (AKI) portends worse clinical outcomes and remains a therapeutic challenge for clinicians. A recent study...
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Predictive performance of two types of urinary biomarkers for renal non-recovery in sepsis-associated acute kidney injury: a prospective observational study
Background and purposeRenal non-recovery is known to have negative prognostic implications in patients suffering from acute kidney injury (AKI)....
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Identification of key genes of anti-programmed death ligand 1 for meningioma immunotherapy by bioinformatic analysis
Meningioma is one of the most common primary tumors in the central nervous system (CNS). A deeper understanding of its molecular characterization...
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Comprehensive analysis of a chemokine- and chemokine receptor family-based signature for patients with lung adenocarcinoma
The clinical significance and comprehensive features of chemokines and their receptors in lung adenocarcinoma (LUAD) have not been clarified. We...
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CC chemokines and receptors in osteoarthritis: new insights and potential targets
Osteoarthritis (OA) is a prevalent degenerative disease accompanied by the activation of innate and adaptive immune systems-associated inflammatory...
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The kidney, COVID-19, and the chemokine network: an intriguing trio
On December 30th 2019, some patients with pneumonia of unknown etiology were reported in the Program for Monitoring Emerging Diseases (ProMED), a...
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Identification and validation of biomarkers of persistent acute kidney injury: the RUBY study
PurposeThe aim of the RUBY study was to evaluate novel candidate biomarkers to enable prediction of persistence of renal dysfunction as well as...
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CircTMC5 promotes gastric cancer progression and metastasis by targeting miR-361-3p/RABL6
BackgroundGastric cancer (GC) is common in East Asia, yet its molecular and pathogenic mechanisms remain unclear. Circular RNAs (circRNAs) are...
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Different roles of protein biomarkers predicting eGFR trajectories in people with chronic kidney disease and diabetes mellitus: a nationwide retrospective cohort study
BackgroundChronic kidney disease (CKD) is a common comorbidity in people with diabetes mellitus, and a key risk factor for further life-threatening...
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Role of platelet to albumin ratio for predicting persistent acute kidney injury in patients admitted to the intensive care unit
BackgroundThe aim of this study was to investigate the prognostic role of platelet to albumin ratio (PAR) and in persistent acute kidney injury...
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Neueste Entwicklungen bei der akuten Nierenschädigung
Acute kidney injury (AKI) is a common problem in critically ill patients and is associated with increased morbidity and mortality. Since 2012, AKI...
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Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury
Critical illness is often complicated by acute kidney injury (AKI). In patients with severe AKI, renal replacement therapy (RRT) is deployed to...
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High Level of Ubiquitin Conjugate Enzyme E2O Indicates Poor Prognosis of Patients with Hepatocellular Carcinoma
ObjectiveUbiquitin conjugate enzyme E2O (UBE2O) is a ubiquitin-conjugating enzyme that has been reported to be involved in tumorigenesis. This study...
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Proenkephalin A 119–159 predicts early and successful liberation from renal replacement therapy in critically ill patients with acute kidney injury: a post hoc analysis of the ELAIN trial
BackgroundRenal replacement therapy (RRT) remains the key rescue therapy for critically ill patients with severe acute kidney injury (AKI). However,...
