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Post-mastectomy reirradiation for ipsilateral T3N0M0 breast tumor relapse: a population-based study
IntroductionPost-mastectomy radiotherapy is commonly recommended for T3N0M0 breast cancer, particularly in the presence of adverse prognostic...
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Ipsilateral breast tumor recurrence after breast-conserving surgery: insights into biology and treatment
Despite modern surgical and irradiation techniques, ipsilateral breast tumor recurrence (IBTR) accounts for 5–15% of all cancer recurrence in women...
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Lysine metabolism is a novel metabolic tumor suppressor pathway in breast cancer
The International Agency for Research on Cancer determined that obesity is the primary preventable cause of breast cancer. The nuclear receptor...
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SCARB2 associates with tumor-infiltrating neutrophils and predicts poor prognosis in breast cancer
BackgroundThe tumor microenvironment (TME) plays a crucial role in various aspects of breast cancer development and metastasis. Nevertheless, the...
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Adipocytes secretome from normal and tumor breast favor breast cancer invasion by metabolic reprogramming
BackgroundAdipose tissue is a major component of breast stroma. This study focused on delineating the effects of adipose stem cells (ASCs) derived...
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RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells
Breast cancer stem cells (BCSC) are presumed to be responsible for treatment resistance, tumor recurrence and metastasis of breast tumors. However,...
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Tumor Characteristics of Bilateral Breast Cancer Compared with Unilateral Breast Cancer
BackgroundBilateral breast cancer (BC) has an incidence of 1 to 3 %. This study aimed to describe the clinicopathologic characteristics and...
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Ketamine promotes breast tumor growth in a mouse breast tumor model involving with high expression of miR-27b-3p and EGFR
Non-medical use of ketamine as an adulterant to ecstasy is more prevalent than amphetamine in Taiwan. Ketamine’s effect on immunosuppression might...
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Duodenal neuroendocrine tumor after bilateral breast cancer with type 1 neurofibromatosis: a case report
BackgroundYoung women with NF1 are at a high risk of develo** breast cancer. Although they are at risk for abdominal tumors, such as...
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Tumor-infiltrating lymphocytes as a predictor of axillary and primary tumor pathological response after neoadjuvant chemotherapy in patients with breast cancer: a retrospective cohort study
PurposeTumor-infiltrating lymphocytes (TILs) can predict complete pathological response (pCR) of tumor in the breast but not so well-defined in the...
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Patient Preference for Surgical Methods for Ipsilateral Breast Tumor Recurrence
BackgroundMastectomy has been the standard surgical treatment for ipsilateral breast tumor recurrence (IBTR). Recently, there has been growing...
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Practice of Tumor Bed Boost in Patients after Oncoplastic Breast-Conserving Surgery
The practice of boost to the tumor bed after treatment with oncoplastic breast-conserving surgery (BCS) remains variable. Using a survey, the present...
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Circulating tumor cells clusters and their role in Breast cancer metastasis; a review of literature
Breast cancer is a significant and deadly threat to women globally. Moreover, Breast cancer metastasis is a complicated process involving multiple...
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Adipose-derived stem cell exosomes promote tumor characterization and immunosuppressive microenvironment in breast cancer
Adipose-derived stem cells (ASC) or autologous fat transplantation could be used to ameliorate breast cancer postoperative deformities. This study...
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A Systematic Review and Meta-analysis of the Role of Preoperative MRI in In-breast Tumor Recurrence After Breast-Conserving Surgery
BackgroundIt is unknown whether the identification of additional tumors in the breast using preoperative magnetic resonance imaging (pMRI) results in...
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Variant allele frequency in circulating tumor DNA correlated with tumor disease burden and predicted outcomes in patients with advanced breast cancer
PurposeIn patients with first-line advanced breast cancer (ABC), the correlation between ctDNA variant allele frequency (VAF) and tumor disease...
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Expression profiling of luminal B breast tumor in Indian women
PurposeIn this study, we aimed at profiling of luminal B breast cancer specific gene expression pattern in Indian women using mRNA-seq and validation...
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Role of Cyclin D1b in Inducing Macrophages Toward a Tumor-associated Macrophage-like Phenotype in Murine Breast Cancer
ObjectiveTumor-associated macrophages (TAMs) of the M2 phenotype are frequently associated with cancer progression. Invasive cancer cells undergoing...
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The prognostic and predictive role of tumor-infiltrating lymphocytes (FoxP3 + and CD8 +) and tumor-associated macrophages in early HER2 + breast cancer
PurposeIn HER2-positive (HER2 +) breast cancer, tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs) may influence the...
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Chronic pulmonary bacterial infection facilitates breast cancer lung metastasis by recruiting tumor-promoting MHCIIhi neutrophils
Breast cancer can metastasize to various organs, including the lungs. The immune microenvironment of the organs to be metastasized plays a crucial...