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Comparison of proportions and prognostic impact of pathological complete response between evaluations of representative specimen and total specimen in primary breast cancer after neoadjuvant chemoradiotherapy: an ancillary study of JCOG0306
BackgroundIn JCOG0306 trial, a phase II study to examine the efficacy of neoadjuvant chemotherapy followed by radiation therapy (NAC-RT) to primary...
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Conventional specimen radiography in breast-conserving therapy: a useful tool for intraoperative margin assessment after neoadjuvant therapy?
PurposeA previous study in our breast unit showed that the diagnostic accuracy of intraoperative specimen radiography and its potential to reduce...
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Systematically higher Ki67 scores on core biopsy samples compared to corresponding resection specimen in breast cancer: a multi-operator and multi-institutional study
Ki67 has potential clinical importance in breast cancer but has yet to see broad acceptance due to inter-laboratory variability. Here we tested an...
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Minimally Invasive Breast Biopsy After Neoadjuvant Systemic Treatment to Identify Breast Cancer Patients with Residual Disease for Extended Neoadjuvant Treatment: A New Concept
BackgroundBreast cancer patients with residual disease after neoadjuvant systemic treatment (NAST) have a worse prognosis compared with those...
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Local Flaps in Breast-Conserving Surgery in Early Breast Cancer Patients: Armamentarium for Breast Surgeon
To describe the technique and outcome of local perforator arteries advancement flap in breast-conserving surgeries (BCS) in patient of early breast...
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Analysis of Specimen Mammography with Artificial Intelligence to Predict Margin Status
BackgroundIntraoperative specimen mammography is a valuable tool in breast cancer surgery, providing immediate assessment of margins for a resected...
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Does conventional specimen radiography after neoadjuvant chemotherapy of breast cancer help to reduce the rate of second surgeries?
PurposeThis is the first study to systematically evaluate the diagnostic accuracy of intraoperative specimen radiography on margin level and its...
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High-Resolution Full-3D Specimen Imaging for Lumpectomy Margin Assessment in Breast Cancer
BackgroundTwo-dimensional (2D) specimen radiography (SR) and tomosynthesis (DBT) for breast cancer yield data that lack high-depth resolution. A...
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Oncoplastic breast conserving surgery versus standard breast conserving surgery for early and locally advanced breast cancer: a retrospective analysis from Sri Lanka
BackgroundBreast aesthetics is becoming increasingly important in breast cancer surgery due to changes in patient expectations and greater emphasis...
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Identifying homologous recombination deficiency in breast cancer: genomic instability score distributions differ among breast cancer subtypes
PurposeA 3-biomarker homologous recombination deficiency (HRD) score is a key component of a currently FDA-approved companion diagnostic assay to...
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Correlating Receptor Status with Nottingham Prognostic Index in Breast Cancer
The biological behavior and prognosis of breast cancer is often unpredictable with a number of factors contributing to the outcome. Nottingham’s...
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Endoscopic mastectomy followed by immediate breast reconstruction with fat grafting for breast cancer
BackgroundAlthough endoscopic mastectomy has been associated with good tolerance and enhanced patient satisfaction, limitations such as the implant...
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Upgrade Rates and Breast Cancer Development Among Germline Pathogenic Variant Carriers with High-Risk Breast Lesions
BackgroundHigh-risk lesions (HRL) of the breast are risk factors for future breast cancer development and may be associated with a concurrent...
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Relation between morphological features of initial breast MRI and breast cancer molecular subtypes
BackgroundBecause different gene receptors might cause each case of breast cancer, the disease is classified as a heterogeneous form because it can...
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Ki-67 and breast cancer prognosis: does it matter if Ki-67 level is examined using preoperative biopsy or postoperative specimen?
PurposeThis study aimed to identify the association between Ki-67 level and the prognosis of patients with breast cancer, regardless of the timing of...
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Breast-conserving surgery versus modified radical mastectomy in T1-2N3M0 stage breast cancer: a propensity score matching analysis
PurposeBreast-conserving surgery (BCS) plus radiotherapy and mastectomy exhibit highly comparable prognoses for early-stage breast cancer; however,...
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Intraoperative Ultrasound-Guided Conserving Surgery for Breast Cancer: No More Time for Blind Surgery
BackgroundBreast-conserving surgery (BCS) still remains a blind surgery despite all available tumor localization methods. Intraoperative ultrasound...
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Prognostic impact of PTK6 expression in triple negative breast cancer
BackgroundThe aim of this study was to investigate the expression of PTK6 in different groups of triple negative breast cancer and its impact on...
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SLC35A2 expression is associated with HER2 expression in breast cancer
The role of SLC35A2 in breast cancer remains poorly understood, with limited available information on its significance. This study aimed to...
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Association of Breast Cancer Subtypes and Clinicopathological Factors with Axillary Lymph Node Positivity Amongst Women with Breast Cancer in Rajasthan: An Observational Analytical Study
Prognostic factors by definition, are capable of providing information on clinical outcomes at the time of diagnosis, independent of therapy. The...