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  1. The Brain–Heart Axis: Neuroinflammatory Interactions in Cardiovascular Disease

    Purpose of Review

    The role of neuroimmune modulation and inflammation in cardiovascular disease has been historically underappreciated. Physiological...

    Jiun-Ruey Hu, Ahmed Abdullah, ... Robert Soufer in Current Cardiology Reports
    Article 23 November 2023

  2. Molecular imaging of the brain–heart axis provides insights into cardiac dysfunction after cerebral ischemia

    Ischemic stroke imparts elevated risk of heart failure though the underlying mechanisms remain poorly described. We aimed to characterize the...

    Nele Hermanns, Viola Wroblewski, ... James T. Thackeray in Basic Research in Cardiology
    Article Open access 24 October 2022

  4. Brain–heart interaction disruption in major depressive disorder: disturbed rhythm modulation of the cardiac cycle on brain transient theta bursts

    Brain neurons support arousal and cognitive activity in the form of spectral transient bursts and cooperate with the peripheral nervous system to...

    Hongliang Zhou, Tingting **ong, ... Qing Lu in European Archives of Psychiatry and Clinical Neuroscience
    Article 15 June 2023

  5. Cardiac optogenetics: regulating brain states via the heart

    Silvia Rodriguez-Rozada, Stefan Frantz, Philip Tovote in Signal Transduction and Targeted Therapy
    Article Open access 30 August 2023

  6. Nested and multipart prospective observational studies, flaming fiasco or efficiently economical?: The Brain, Bone, Heart case study

    Background

    Collecting new data from cross-sectional/survey and cohort observational study designs can be expensive and time-consuming. Nested...

    C. Christina Mehta, Kimberly S. Hagen, ... Ighovwerha Ofotokun in BMC Medical Research Methodology
    Article Open access 25 July 2022

  7. Cytotoxicity associated with acute and chronic administration of synthetic cannabinoids “Strox” in the brain, liver, heart, and testes of male albino rats: histological and immunohistochemical study

    Background

    Synthetic cannabinoids are one of the largest groups of new psychoactive substances that invaded Egypt’s drug abuse market over the past...

    Wafaa M. Abdelmoneim, Marwa H. Bakr, ... Nora Z. Abdellah in Egyptian Journal of Forensic Sciences
    Article Open access 09 February 2023

  8. Detrimental effects of COVID-19 in the brain and therapeutic options for long COVID: The role of Epstein–Barr virus and the gut–brain axis

    The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a...

    Kenji Hashimoto in Molecular Psychiatry
    Article Open access 04 July 2023

  9. Atypical pituitary hormone-target tissue axis

    A long-held belief is that pituitary hormones bind to their cognate receptors in classical target glands to actuate their manifold functions....

    Chao Xu, Zhao He, ... Jiajun Zhao in Frontiers of Medicine
    Article 27 February 2023

  11. Modelling [18F]LW223 PET data using simplified imaging protocols for quantification of TSPO expression in the rat heart and brain

    Purpose

    To provide a comprehensive assessment of the novel 18 kDa translocator protein (TSPO) radiotracer, [ 18 F]LW223, kinetics in the heart and...

    Mark G. MacAskill, Catriona Wimberley, ... Adriana A. S. Tavares in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 02 August 2021

  12. Current understanding and future perspectives of brain–heart–kidney axis in psoriatic arthritis

    Psoriatic arthritis (PsA) patients are at a higher risk of systemic inflammatory sequelae, leading to microalbuminuria, cardiovascular (CVD) and...

    George Markousis-Mavrogenis, Michael T. Nurmohamed, ... Sophie I. Mavrogeni in Rheumatology International
    Article 27 June 2020

  13. Modulation of Heart and Brain Function by Surah Al-Rehman Recitation Among Distressed Diabetic Patients in Pakistan

    Distress causes psychophysiological alterations that affect autonomic function. The current study explores psychophysiological modulation in diabetic...

    Umair Majeed, Meha Fatima Aftab, ... Muhammad Sameer Qureshi in Journal of Religion and Health
    Article 23 September 2021

  14. Gut-derived immune cells and the gut-lung axis in ARDS

    The gut serves as a vital immunological organ orchestrating immune responses and influencing distant mucosal sites, notably the respiratory mucosa....

    Mairi Ziaka, Aristomenis Exadaktylos in Critical Care
    Article Open access 04 July 2024

  15. Decreased nocturnal heart rate variability and potentially related brain regions in arteriosclerotic cerebral small vessel disease

    Background

    To assess heart rate variability (HRV) among patients with arteriosclerotic cerebral small vessel disease (CSVD) by comparing with control...

    Miaoyi Zhang, Huan Yu, ... Jianhui Fu in BMC Neurology
    Article Open access 16 September 2021

  16. lncRNA Gm20257 alleviates pathological cardiac hypertrophy by modulating the PGC-1α–mitochondrial complex IV axis

    Pathological cardiac hypertrophy, a major contributor to heart failure, is closely linked to mitochondrial function. The roles of long noncoding RNAs...

    Tong Yu, Qiang Gao, ... Hongli Shan in Frontiers of Medicine
    Article 27 June 2024

  17. Utility of fetal cardiac magnetic resonance imaging in assessing the cardiac axis in fetuses with congenital heart disease

    Background

    Fetal dedicated echocardiography is the standard to measure the fetal cardiac axis. However, fetal screening ultrasound (US) or fetal...

    Ke Liu, Ming Zhu, ... Su-Zhen Dong in Pediatric Radiology
    Article 05 January 2023

  18. Regulating effects of Neiguan (PC6) and Gongsun (SP4) on hypothalamic-pituitary-adrenal axis in rats with functional dyspepsia

    Objective

    To investigate the effects and the possible mechanisms of Neiguan (PC6) and Gongsun (SP4) on the hypothalamic-pituitary-adrenal (HPA) axis...

    Bowen **ng, Simin Qin, ... Weiai Liu in Journal of Acupuncture and Tuina Science
    Article 19 August 2023

  19. Microbiota-gut-brain axis: relationships among the vagus nerve, gut microbiota, obesity, and diabetes

    Aims

    The purpose of this review is to explore the interconnected pathways of the microbiota-gut-brain axis (MGBA), focusing on the roles of the vagus...

    Susanna Longo, Stefano Rizza, Massimo Federici in Acta Diabetologica
    Article Open access 14 April 2023

  20. Regulation of Keap1-Nrf2 axis in temporal lobe epilepsy—hippocampal sclerosis patients may limit the seizure outcomes

    Background

    Accumulation of reactive oxygen species (ROS) exacerbates neuronal loss during seizure-induced excitotoxicity. Keap1 (Kelch-like...

    Madhamanchi Kishore, Madhamanchi Pradeep, ... Phanithi Prakash Babu in Neurological Sciences
    Article 11 July 2023
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