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Comparison of whole brain radiation therapy for synchronous brain metastases with irradiation protecting the hippocampus versus whole brain radiotherapy for sequential brain metastases to boost irradiation in the treatment of brain metastases from SCLC: study protocol for a randomized controlled trial
BackgroundThis study is in regard to the comparison of whole brain radiation therapy for synchronous brain metastases with irradiation protecting the...
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Current Management of Brain Metastases in Breast Cancer
This study aims to evaluate the clinical features, prognostic factors, and survival of patients treated in our clinic for brain metastases of brain...
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Patterns of brain metastases response to immunotherapy with pembrolizumab
PurposeCentral nervous system (CNS) metastases from lung cancers and melanoma, significantly contribute to morbidity and mortality. Despite advances...
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Systemic Therapy for Melanoma Brain and Leptomeningeal Metastases
Melanoma has a high propensity to metastasize to the brain which portends a poorer prognosis. With advanced radiation techniques and targeted...
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Harnessing immunotherapy for brain metastases: insights into tumor–brain microenvironment interactions and emerging treatment modalities
Brain metastases signify a deleterious milestone in the progression of several advanced cancers, predominantly originating from lung, breast and...
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Incidence, Risk Factors, and Prognosis of Patients with Hepatocellular Carcinoma and Brain Metastases
ObjectiveBrain metastases significantly impact the clinical course of patients with hepatocellular carcinoma (HCC). This study aimed to examine the...
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De novo versus recurrent metastatic breast cancer affects the extent of brain metastases
PurposeWe aimed to identify factors associated with the extent of brain metastases in patients with breast cancer to help distinguish brain...
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A long-term survival case of bladder cancer with distant metastases: abscopal effect of brain metastases after stereotactic radiotherapy with immune checkpoint blockade therapy to lung metastases
Brain metastases from bladder cancer are rare, with a poor prognosis. There is no standard treatment for bladder cancer with brain metastases; thus,...
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Differentiation of multiple brain metastases and glioblastoma with multiple foci using MRI criteria
ObjectiveGlioblastoma with multiple foci (mGBM) and multiple brain metastases share several common features on magnetic resonance imaging (MRI). A...
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Outcome of brain metastases from adrenocortical carcinoma: a pooled analysis
PurposeBrain metastases rarely complicate the natural history of patients with adrenocortical carcinoma (ACC). No information is available regarding...
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Mutational signatures of synchronous and metachronous brain metastases from lung adenocarcinoma
Brain metastasis (BM) is an important cause of mortality for cancer patients. Many patients were diagnosed with brain metastases at their first visit...
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Akinetopsia (visual motion blindness) associated with brain metastases: a case report
Akinetopsia is a rare neurological syndrome characterized by an impaired perception of movement, often resulting from brain damage due to ischemia,...
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Effect of sarcopenia and frailty on outcomes among patients with brain metastases
PurposeSarcopenia and frailty have been associated with increased mortality and duration of hospitalization in cancer. However, data investigating...
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Brain metastases of sarcoma: a rare phenomenon in rare tumours
The usual site for distant metastases of sarcoma is lungs, while brain metastasis (BM) occurs much less frequently and usually late in the disease...
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DEGRO guideline for personalized radiotherapy of brain metastases and leptomeningeal carcinomatosis in patients with breast cancer
PurposeThe aim of this review was to evaluate the existing evidence for radiotherapy for brain metastases in breast cancer patients and provide...
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SNP array genomic analysis of matched pairs of brain and liver metastases in primary colorectal cancer
PurposeBrain metastasis formation is a rare and late event in colorectal cancer (CRC) patients and associated with poor survival. In contrast to...
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Survival analysis of patients with brain metastases at initial breast cancer diagnosis over the last decade
PurposeThere have been significant advances in the treatment of metastatic breast cancer (BC) over the past years, and long-term outcomes after a...
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Effect of different optimization parameters in single isocenter multiple brain metastases radiosurgery
PurposeAutomated treatment planning for multiple brain metastases differs from traditional planning approaches. It is therefore helpful to understand...
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Stereotactic radiosurgery for patients with brain metastases from gastroesophageal cancers
BackgroundThe prognosis of patients with brain metastases from gastroesophageal (GE) cancers remains unclear despite recent advances in systemic...
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MET receptor serves as a promising target in melanoma brain metastases
The development of brain metastases hallmarks disease progression in 20–40% of melanoma patients and is a serious obstacle to therapy. Understanding...
