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Estradiol increases cortical and trabecular bone accrual and bone strength in an adolescent male-to-female mouse model of gender-affirming hormone therapy
The effects of gender-affirming hormone therapy on the skeletal integrity and fracture risk in transitioning adolescent trans girls are unknown. To...
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Pubertal increment in insulin resistance is negatively related to lumbar bone mineral density in 18-year-old males
SummaryTransient insulin resistance seen during puberty is expected to favour body growth, but our results show that increment in insulin resistance...
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Chronic kidney disease mineral bone disorder in childhood and young adulthood: a ‘growing’ understanding
Chronic kidney disease (CKD) mineral and bone disorder (MBD) comprises a triad of biochemical abnormalities (of calcium, phosphate, parathyroid...
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Effect of soluble corn fibre and calcium supplementation on bone mineral content and bone mineral density in preadolescent Malaysian children—a double-blind randomised controlled trial (PREBONE-Kids Study)
SummarySoluble corn fibre (SCF) with calcium did not improve bone indices after 1 year in preadolescent children.
IntroductionSCF has been reported...
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Low bone mineral density is associated with fatty liver disease and respiratory illness in a pediatric mortality sample
SummaryThis study finds that fatty liver disease is associated with low bone density in a pediatric mortality sample. Since non-alcoholic fatty liver...
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Dairy product consumption, eating habits, sedentary behaviour and physical activity association with bone mineral density among adolescent boys: a cross-sectional observational study
BackgroundDuring childhood and adolescence, skeletal microarchitecture and bone mineral density (BMD) undergo significant changes. Peak bone mass is...
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Bone mineral density in young adults 5 to 11 years after adolescent metabolic and bariatric surgery for severe obesity compared to peers
ObjectiveMetabolic and bariatric surgery (MBS) is associated with decreased bone mineral density (BMD) in adults. The long-term impact of MBS during...
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Puberty and Bone Health in Chronic Disease
Linear growth, onset of and progress through puberty are all adversely affected by chronic diseases during childhood and adolescence. Peak bone mass...
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Dietary content and combined training, but not daily physical activity, are associated with 6-month bone mineral changes in adolescents with obesity: A Secondary analysis of the PAC-MAnO trial
PurposeThe present study aimed to explore the influence of diet and physical activity (PA) changes on bone mineral content (BMC) and density (BMD)...
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Association of total body fat and fat distribution with bone mineral density among children and adolescents aged 6–17 years from Guangzhou, China
This study aimed to assess the associations of total body fat and fat distribution with bone mineral density (BMD) among children and adolescents in...
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Bone Material Properties in Bone Diseases Affecting Children
Purpose of ReviewMetabolic and genetic bone disorders affect not only bone mass but often also the bone material, including degree of mineralization,...
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Resistance training presents beneficial effects on bone development of adolescents engaged in swimming but not in impact sports: ABCD Growth Study
BackgroundSports practice during adolescence is important to enhance bone development, although it may provide different effects depending on the...
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A longitudinal genome-wide association study of bone mineral density mean and variability in the UK Biobank
SummaryBone mineral density (BMD) is an essential predictor of osteoporosis and fracture. We conducted a genome-wide trajectory analysis of BMD and...
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Inflammation induces stunting by lowering bone mass via GH/IGF-1 inhibition in very preterm infants
BackgroundSustained systemic inflammatory response (SIR) was associated with poor postnatal growth in very preterm infants (VPI). We hypothesize that...
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Growth, body composition and bone mineral density among pubertal male athletes: intra-individual 12-month changes and comparisons between soccer players and swimmers
BackgroundPuberty is a period of intense changes in human body and, additionally, participation in sports is viewed as prominent form of physical...
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Bone health and physical activity in adolescents with juvenile idiopathic arthritis: a cross-sectional case-control study
BackgroundAdolescents with juvenile idiopathic arthritis (JIA) tend to engage in less physical activity than their typically develo** peers....
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The aetiology of atypical bone health in individuals with Down syndrome
PurposeTrisomy 21 (T21), more commonly known as Down syndrome (DS) is a genetic condition where every cell in the body has an additional copy of...
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Bone accrual over 18 months of participation in different loading sports during adolescence
SummaryThis study investigated the impact and non-impact sports on bone mineral density accrual in adolescents over 18 months. The impact sports were...
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Bone Health in Young Athletes: a Narrative Review of the Recent Literature
Purpose of ReviewThe aim of this review is to discuss the most recent published scientific evidence regarding bone health in the pediatric athlete.
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Impact of changes in fat mass and lean soft tissue on bone mineral density accrual in adolescents engaged in different sports: ABCD Growth Study
SummaryBody composition can have a significant impact on bone mineral density (BMD) in pediatric patients and may cause bone disease. This study...
