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The effect of cardiopulmonary bypass on blood thiamine concentration and its association with post-operative lactate concentration
ObjectiveCardiothoracic surgery is a large field in Australia, and evidence suggests post-cardiopulmonary bypass (CPB) hyperlactataemia is associated...
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Effect of early peri-operative arterial lactate concentration level ratios on post-hepatectomy liver failure
BackgroundPost-hepatectomy liver failure (PHLF) is a serious complication after hepatectomy and a major cause of death. The current criteria for PHLF...
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Maternal and umbilical cord blood lactate for predicting perinatal death: a secondary analysis of data from a randomized controlled trial
BackgroundIn high resource settings, lactate and pH levels measured from fetal scalp and umbilical cord blood are widely used as predictors of...
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Factors associated with elevated blood lactate levels in patients undergoing maintenance hemodialysis
Factors associated with chronic elevation of the blood lactate levels in patients undergoing chronic maintenance hemodialysis (hereinafter,...
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The origin of the maximal lactate steady state (MLSS)
The maximal lactate steady state, abbreviated as MLSS, is the maximal exercise intensity where the concentration of earlobe capillary or arterial...
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Postconditioning with Lactate-Enriched Blood for Reducing Lethal Reperfusion Injury in Humans
Ischemic myocardium cannot survive without reperfusion. However, reperfusion of the ischemic myocardium paradoxically induces myocyte death; this...
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The value of elevated cerebrospinal fluid lactate concentrations in post-neurosurgical bacterial meningitis
Bacterial meningitis is a serious complication after neurosurgery and has a high mortality rate. Early diagnosis and timely treatment are crucial or...
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Effects of High-Intensity Interval Training Protocols on Blood Lactate Levels and Cognition in Healthy Adults: Systematic Review and Meta-Regression
BackgroundSome health benefits from high-intensity interval training (HIIT) are facilitated by peripheral blood lactate levels. However, the lactate...
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Accuracy of a point-of-care blood lactate measurement device in a prehospital setting
Point-of-care blood lactate is a promising prognostic biomarker of short-term mortality risk. Portable lactate meters need validation in the...
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Correlation of Serum Lactate Levels, Perfusion Index and Plethysmography Variability Index With Invasive Blood Pressure in Late Preterm and Term Infants With Shock
ObjectiveTo study the correlation of objective parameters for diagnosing shock viz., perfusion index (PI), plethysmography variability index (PVI)...
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Does Lactate Clearance Predict Short-Term Mortality in Pulmonary Embolism?
Plasma lactate level of ≥ 2 mmol/L can predict pulmonary embolism (PE)-associated adverse outcomes but has led to the question of if monitoring...
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Initial lactate levels linked to oliguria in term neonates with perinatal asphyxia
BackgroundOliguria is a sign of impaired kidney function and has been shown to be an early predictor of adverse prognoses in patients with acute...
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The combination of lactate level, lactate clearance and APACHE II score better predicts short-term outcomes in critically Ill patients: a retrospective cohort study
BackgroundThe mortality rate is high in critically ill patients due to the difficulty of diagnosis and treatment. Thus, it is very important to...
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Predictive clinical utility of pre-hospital point of care lactate for transfusion of blood product in patients with suspected traumatic haemorrhage: derivation of a decision-support tool
IntroductionPre-hospital emergency medical teams can transfuse blood products to patients with suspected major traumatic haemorrhage. Common...
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Target blood pressure management during cardiopulmonary bypass improves lactate levels after cardiac surgery: a randomized controlled trial
BackgroundHyperlactatemia is associated with a poor prognosis in cardiac surgery patients. This study explored the impact of target blood pressure...
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Lactate Decreases Bortezomib Sensitivity and Predicts Poor Clinical Outcomes of Multiple Myeloma
ObjectiveMetabolic disorders are regarded as hallmarks of multiple myeloma (MM) and are responsible for rapid cancer cell proliferation and tumor...
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Tissue oxygen saturation is predictive of lactate clearance in patients with circulatory shock
BackgroundTissue oxygen saturation (StO 2 ) decrease could appear earlier than lactate alteration. However, the correlation between StO 2 and lactate...
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Serum lactate normalization time associated with prolonged postoperative ileus after surgical management of the small bowel and/or mesenteric injuries
Back ground: Determining the optimal timing of postoperative oral feeding in trauma patients who have undergone abdominal surgery with small bowel...
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MCT4-dependent lactate transport: a novel mechanism for cardiac energy metabolism injury and inflammation in type 2 diabetes mellitus
Diabetic cardiomyopathy (DCM) is a major contributor to mortality in diabetic patients, characterized by a multifaceted pathogenesis and limited...
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Heart Rate Variability-Derived Thresholds for Exercise Intensity Prescription in Endurance Sports: A Systematic Review of Interrelations and Agreement with Different Ventilatory and Blood Lactate Thresholds
BackgroundExercise intensities are prescribed using specific intensity zones (moderate, heavy, and severe) determined by a ‘lower’ and a ‘higher’...