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Toxicology knowledge graph for structural birth defects
BackgroundBirth defects are functional and structural abnormalities that impact about 1 in 33 births in the United States. They have been attributed...
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Maternal physical activity, sitting, and risk of non-cardiac birth defects
BackgroundThe relationship between maternal physical activity (PA)/sitting and birth defects is largely unexplored. We examined whether pre-pregnancy...
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Perinatal deaths from birth defects in Hunan Province, China, 2010–2020
ObjectiveTo describe the perinatal mortality rate (PMR) of birth defects and to define the relationship between birth defects (including a broad...
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Multivariate logistic regression analysis of risk factors for birth defects: a study from population-based surveillance data
ObjectiveTo explore risk factors for birth defects (including a broad range of specific defects).
MethodsData were derived from the Population-based...
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Perinatal prevalence of birth defects in the Mainland of China, 2000–2021: a systematic review and meta-analysis
BackgroundAlthough birth defects are of great concern globally, the latest national prevalence has not yet been quantified in China. We conducted a...
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Preconception folic acid supplementation for the prevention of birth defects: a prospective, population-based cohort study in mainland China
BackgroundFolic acid supplementation is recommended for reducing the risk of birth defects. We aimed to assess the protective association of...
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Global, regional, and national incidence and mortality of congenital birth defects from 1990 to 2019
The study aims to estimate the trends in incidence and mortality of congenital birth defects at global, regional, and national levels from 1990 to...
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Association between usage of household cooking fuel and congenital birth defects-18 months multi-centric cohort study in Nepal
Background- An estimated 240,000 newborns die worldwide within 28 days of birth every year due to congenital birth defect. Exposure to poor indoor...
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Trends in the incidence of major birth defects after assisted reproductive technologies in Lombardy Region, Northern Italy
PurposeThe incidence of birth defects is increased in children born after assisted reproductive technologies (ART). However, changes in ART over time...
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Determinants of externally visible birth defects among perinatal deaths at Adama Comprehensive Specialized Hospital: a case-control study
BackgroundBirth defects (BDs) are the major causes of infant morbidity and mortality in both developed and develo** countries. Regardless of their...
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Birth Defects in India Epidemiology and Public Health Implications
This book presents the epidemiology of birth defects and their public health and social implications in India. As neglected childhood disorders,...
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Birth defect co-occurrence patterns in the Texas Birth Defects Registry
BackgroundThe population-level landscape of co-occurring birth defects among infants without a syndromic diagnosis is not well understood.
...
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Risks of obstructive genitourinary birth defects in relation to trihalomethane and haloacetic acid exposures: expanding disinfection byproduct mixtures analyses using relative potency factors
BackgroundSome disinfection byproducts (DBPs) are teratogens based on toxicological evidence. Conventional use of predominant DBPs as proxies for...
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Prenatal exposure to wildfire-related air pollution and birth defects in Brazil
BackgroundBirth defects are a major cause of poor health outcomes during both childhood and adulthood. A growing body of evidence demonstrated...
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Determinants of neural tube defects among women who gave birth in hospitals in Eastern Ethiopia: evidence from a matched case control study
IntroductionNeural tube defects (NTDs) are severe birth defects caused by nutritional, genetic or environmental factors. Because NTDs continue to...
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Association of China’s two-child policy with changes in number of births and birth defects rate, 2008–2017
BackgroundIn October 2015, China’s one-child policy was universally replaced by a so-called two-child policy. This study investigated the association...
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Birth prevalence of neural tube defects in eastern Africa: a systematic review and meta-analysis
BackgroundNeural tube defects (NTDs) are associated with high rates of neonatal mortality and morbidity worldwide. The promotion of folic acid...
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Urban–rural residence and birth defects prevalence in Texas: a phenome-wide association study
BackgroundSome assessments indicate the prevalence of certain birth defects varies by urban–rural status. We evaluated associations between...
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How do Age at the Surgery and Birth Weight Influence Post-Operative Anthropometric Parameters in Infants with Surgical Closure of Large Ventricular Septal Defects? A Prospective Cohort Study from a Lower-Middle-Income Country
Closure of the large ventricular septal defects (VSD) in infancy can lead to normalization of growth, but data are limited. Our study is done to...
