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Key subphenotypes of bipolar disorder are differentially associated with polygenic liabilities for bipolar disorder, schizophrenia, and major depressive disorder
Bipolar disorder (BD) features heterogenous clinical presentation and course of illness. It remains unclear how subphenotypes associate with genetic...
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Clinical distinctions in symptomatology and psychiatric comorbidities between misdiagnosed bipolar I and bipolar II disorder versus major depressive disorder
BackgroundTo explore the demographic and clinical features of current depressive episode that discriminate patients diagnosed with major depressive...
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Cognitive behavioural therapy for social anxiety disorder in people with bipolar disorder: a case series
BackgroundSocial anxiety disorder increases the likelihood of unfavourable outcomes in people with bipolar disorder. Cognitive behavioural therapy...
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Depressive disorder, bipolar disorder, and associated factors among adults, in the Eastern part of Ethiopia
BackgroundDepressive disorder is one of the severe and common mental illnesses in the general population. Bipolar disorder is a severe, persistent...
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CaMKK2 as an emerging treatment target for bipolar disorder
Current pharmacological treatments for bipolar disorder are inadequate and based on serendipitously discovered drugs often with limited efficacy,...
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Suspected geriatric onset of attention-deficit/hyperactivity disorder in a patient with comorbid bipolar disorder
BackgroundAn increasing number of adults over 60 years old are presenting with requests for treatment of attention-deficit/hyperactivity disorder...
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Clinical characteristics indexing genetic differences in bipolar disorder – a systematic review
Bipolar disorder is a heterogenous condition with a varied clinical presentation. While progress has been made in identifying genetic variants...
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Obsessions and suicidality in youth suffering from bipolar I disorder
BackgroundObsessive compulsive disorder (OCD) is a common comorbidity with bipolar disorder, a comorbidity that is known to increase suicide risk....
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The research landscape of bipolar disorder in Germany: productive, but underfunded
BackgroundThe recurrent mental illness bipolar disorder is a major burden on the healthcare system, which underlines the importance of research into...
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Temporal changes of gene expression in health, schizophrenia, bipolar disorder, and major depressive disorder
The molecular events underlying the development, manifestation, and course of schizophrenia, bipolar disorder, and major depressive disorder span...
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Appetite hormone dysregulation and executive dysfunction among adolescents with bipolar disorder and disruptive mood dysregulation disorder
Appetite hormone dysregulation may play a role in the pathomechanisms of bipolar disorder and chronic irritability. However, its association with...
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Development and multi-site external validation of a generalizable risk prediction model for bipolar disorder
Bipolar disorder is a leading contributor to disability, premature mortality, and suicide. Early identification of risk for bipolar disorder using...
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Biomarkers of Bipolar Disorder in Late Life: An Evidence-Based Systematic Review
Purpose of ReviewReview the current evidence on biomarkers for bipolar disorder in the older adults. We conducted a systematic search of PubMed...
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Predictors of Response to rTMS in Severe Mental Illnesses- Schizophrenia and Bipolar Disorder
Purpose of ReviewPractice recommendations now include the use of repetitive transcranial magnetic stimulation (rTMS) in the treatment of various...
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Inflammatory mediators in major depression and bipolar disorder
Major depressive disorder (MDD) and bipolar disorder (BD) are highly disabling illnesses defined by different psychopathological, neuroimaging, and...
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A bibliometric and visual analysis of cognitive function in bipolar disorder from 2012 to 2022
IntroductionBipolar disorder (BD) is a chronic psychiatric disorder that combines hypomania or mania and depression. The study aims to investigate...
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Real-world predictors of divorce among outpatients with bipolar disorder: sex differences and clinical implications
BackgroundBipolar disorder is a mental illness characterized by recurring episodes of mania and depression and is known to cause social impairment....
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Developmental manifestations of polygenic risk for bipolar disorder from infancy to middle childhood
Knowledge on how genetic risk for bipolar disorder manifests in developmental, emotional or behavioral traits during childhood is lacking. This issue...
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Oxidatively-induced DNA base damage and base excision repair abnormalities in siblings of individuals with bipolar disorder DNA damage and repair in bipolar disorder
Previous evidence suggests elevated levels of oxidatively-induced DNA damage, particularly 8-hydroxy-2’-deoxyguanosine (8-OH-dG), and abnormalities...
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Clinical and genetic contributions to medical comorbidity in bipolar disorder: a study using electronic health records-linked biobank data
Bipolar disorder is a chronic and complex polygenic disease with high rates of comorbidity. However, the independent contribution of either diagnosis...
