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Assessment of ChatGPT’s adherence to ETA-thyroid nodule management guideline over two different time intervals 14 days apart: in binary and multiple-choice queries
ObjectiveArtificial intelligence (AI) has significant potential in healthcare, particularly in providing decision-support in specialized domains like...
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Optimal futility stop** boundaries for binary endpoints
BackgroundGroup sequential designs incorporating the option to stop for futility at the time point of an interim analysis can save time and...
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Valuing the SF-6Dv2 in the capital of Iran using a discrete choice experiment with duration
BackgroundThe second version of the Short-Form 6-Dimension (SF-6Dv2) classification system has recently been developed. The objective of this study...
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Extension of a conditional performance score for sample size recalculation rules to the setting of binary endpoints
BackgroundSample size calculation is a central aspect in planning of clinical trials. The sample size is calculated based on parameter assumptions,...
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An empirical evaluation of approximate and exact regression-based causal mediation approaches for a binary outcome and a continuous or a binary mediator for case-control study designs
BackgroundIn the causal mediation analysis framework, several parametric regression-based approaches have been introduced in past years for...
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Pregnancy in Transmasculine, Non-binary, and Gender Expansive Patients
Purpose of ReviewTransgender, non-binary, and gender expansive (TNGE) patients may choose to become pregnant and will require pregnancy-related care....
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Binary classification with fuzzy logistic regression under class imbalance and complete separation in clinical studies
BackgroundIn binary classification for clinical studies, an imbalanced distribution of cases to classes and an extreme association level between the...
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Statistical recommendations for count, binary, and ordinal data in rare disease cross-over trials
BackgroundRecommendations for statistical methods in rare disease trials are scarce, especially for cross-over designs. As a result various...
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The association between internet use and the choice of medical institution among Chinese older adults
BackgroundAs older people have complex medical needs and still encounter challenges in accessing online health information, the relationship between...
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Rural healthcare professionals’ participation in Medical Assistance in Dying (MAiD): beyond a binary decision
BackgroundMedical Assistance in Dying (MAiD) was legalized in Canada in 2016 and amended in 2021. At the time that this study was conducted, the...
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Substance use patterns among a global sample of transgender and non-binary people during the COVID-19 pandemic
BackgroundTransgender and non-binary (TNB) people are at high risk of substance misuse compared to cisgender individuals. Few studies have described...
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A change in strategy for filter choice leads to improved filter retrieval rates
Objective: To assess whether a new strategy for the choice of inferior vena cava filter placed would improve filter retrieval rates at our...
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Sample size determination for external pilot cluster randomised trials with binary feasibility outcomes: a tutorial
Justifying sample size for a pilot trial is a reporting requirement, but few pilot trials report a clear rationale for their chosen sample size....
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An optimization framework to guide the choice of thresholds for risk-based cancer screening
It is uncommon for risk groups defined by statistical or artificial intelligence (AI) models to be chosen by jointly considering model performance...
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A Bayesian Bernoulli-Exponential joint model for binary longitudinal outcomes and informative time with applications to bladder cancer recurrence data
BackgroundA variety of methods exist for the analysis of longitudinal data, many of which are characterized with the assumption of fixed visit time...
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Burden of Topical Treatments in Psoriasis and Preferred Criteria of Choice: A Survey-Based Evaluation of Patients in Europe
IntroductionTopical treatments (TT) are widely used in psoriasis management. While psoriasis itself has been associated with diminished quality of...
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Balloon angioplasty as first-choice recanalization strategy for intracranial atherosclerosis-related emergent large vessel occlusion with small clot burden
PurposeThe optimal primary recanalization strategy for intracranial atherosclerosis-related emergent large vessel occlusion (ICAS-ELVO) remains...
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Preferences for the Societal Impacts of a Pandemic when it Transitions into an Endemic: A Discrete Choice Experiment
BackgroundThe stage of the pandemic significantly affects people’s preferences for (the societal impacts of) COVID-19 policies. No discrete choice...
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Comparing Preferences for Disease Profiles: A Discrete Choice Experiment from a US Societal Perspective
ObjectivesThere is increasing interest in expanding the elements of value to be considered when making health policy decisions. To help inform value...
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Associations Among Family Caregivers’ Perceptions of Loneliness, Choice, and Purpose: a Comparative Analysis Between Non-Hispanic Black Caregivers and Non-Hispanic White Caregivers in a Population-Based Sample
BackgroundLoneliness is a frequent experience among family members engaging in caregiving responsibilities and may vary across racial and ethnic...
