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Ameliorative potential of betaine against arsenite-induced hepatotoxicity and nephrotoxicity
Considering several limitations as well as accompanying side effects of currently available arsenic antidotes, it is essential to conduct research...
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Effects of betaine on pentylenetetrazol-induced convulsions during estrus cycle in rat
Catamenial seizures refer to a form of epilepsy that occurs in women as a result of hormonal imbalances during the menstrual cycle. The purpose of...
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Serum betaine and dimethylglycine in mid-pregnancy and the risk of gestational diabetes mellitus: a case-control study
PurposeTo investigate the associations of choline, betaine, dimethylglycine (DMG), L-carnitine, and Trimethylamine-N-oxide (TMAO) with the risk of...
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The association of serum betaine concentrations with the risk of new-onset cancers: results from two independent nested case-control studies
Evidence from epidemiologic studies on the association of circulating betaine levels with the incident risk of cancer has been inconsistent. We aimed...
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Alleviative effect of betaine against copper oxide nanoparticles-induced hepatotoxicity in adult male albino rats: histopathological, biochemical, and molecular studies
BackgroundCopper oxide nanoparticles (CuO-NPs) have gained interest due to their availability, efficiency, and their cost-effectiveness. Betaine is...
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Distinguishing benign and malignant thyroid nodules using plasma trimethylamine N-oxide, carnitine, choline and betaine
PurposeTrimethylamine N-oxide (TMAO), a gut microbiome–derived metabolite, and its precursors (carnitine, choline, betaine) have not been fully...
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Dietary choline and betaine intake, cardio-metabolic risk factors and prevalence of metabolic syndrome among overweight and obese adults
BackgroundCholine is an important metabolite involved in phospholipids synthesis, including serum lipids, and is the immediate precursor of betaine....
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Efficacy and pharmacokinetics of betaine in CBS and cblC deficiencies: a cross-over randomized controlled trial
BackgroundBetaine is an “alternate” methyl donor for homocysteine remethylation catalyzed by betaine homocysteine methyltransferase (BHMT), an enzyme...
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The Role of Betaine in Patients With Chronic Kidney Disease: a Narrative Review
Purpose of ReviewThis narrative review aimed to explore the functions of betaine and discuss its role in patients with chronic kidney disease (CKD).
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The interactive relationship of dietary choline and betaine with physical activity on circulating creatine kinase (CK), metabolic and glycemic markers, and anthropometric characteristics in physically active young individuals
BackgroundThere is conflicting evidence on the relationship between dietary choline and betaine with metabolic markers and anthropometric...
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5-Aminovaleric acid betaine predicts impaired glucose metabolism and diabetes
Background5-Aminovaleric acid betaine (5-AVAB) has recently been identified as a diet and microbial-dependent factor inducing obesity and hepatic...
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Association between dietary choline and betaine intake and 10.6-year cardiovascular disease in adults
BackgroundSeveral studies have assessed the association between dietary choline and betaine and cardiovascular disease (CVD), but their results are...
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Betaine attenuate chronic restraint stress-induced changes in testicular damage and oxidative stress in male mice
ScopeMale fertility and sperm quality are negatively affected by psychological stress. Chronic restraint stress (CRS) is a common psychological...
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Protective effect of betaine against gentamicin-induced renal toxicity in mice: a biochemical and histopathological study
Considering the role of oxidative stress as a molecular mechanism underlying the deleterious side effects of gentamicin, applying antioxidants is...
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Effects of chronic betaine supplementation on performance in professional young soccer players during a competitive season: a double blind, randomized, placebo-controlled trial
ObjectiveVarious nutritional strategies are adopted for athletes to maintain and to improve performance during the competition season. Betaine may...
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The association of dietary choline and betaine and anthropometric measurements among Iranian children: a cross-sectional study
BackgroundPrevious studies have suggested that choline and betaine are associated with improved anthropometric measures including, BMI and waist...
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Effects of 14-weeks betaine supplementation on pro-inflammatory cytokines and hematology status in professional youth soccer players during a competition season: a double blind, randomized, placebo-controlled trial
ObjectiveSystemic elevations in pro-inflammatory cytokines are a marker of non-functional over reaching, and betaine has been shown to reduce the...
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The effects of 14-week betaine supplementation on endocrine markers, body composition and anthropometrics in professional youth soccer players: a double blind, randomized, placebo-controlled trial
ObjectiveBetaine supplementation may enhance body composition outcomes when supplemented chronically during an exercise program. The purpose of this...
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Association of Maternal Betaine-Homocysteine Methyltransferase (BHMT) and BHMT2 Genes Polymorphisms with Congenital Heart Disease in Offspring
To systematically explore the association of single nucleotide polymorphisms (SNPs) of maternal BHMT and BHMT2 genes with the risk of congenital...
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In vivo: maternal betaine supplementation normalized fetal growth in diabetic pregnancy
PurposeDiabetes alters maternal metabolism and can lead to aberrant fetal growth. In addition to insulin treatment, nutritional diet interventions...
