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Cost Analysis of Aprotinin Reintroduction in French Cardiac Surgery Centres: A Real-World Data-Based Analysis
IntroductionThe European Medicines Agency restored aprotinin (APR) use for preventing blood loss in patients undergoing isolated coronary artery...
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Intraoperative anaphylaxis due to aprotinin after local application of fibrin sealant diagnosed by skin tests and basophil activation tests: a case report
BackgroundThere are few cases of anaphylaxis after local application of fibrin sealant diagnosed by skin tests.
Case presentationA 49-year-old woman...
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Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental cardiopulmonary bypass
BackgroundAcute kidney injury is a severe complication following cardiopulmonary bypass (CPB) and is associated with capillary leakage and...
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Performance of 99mTc-aprotinin scintigraphy for diagnosing light chain (AL) cardiac amyloidosis confirmed by endomyocardial biopsy
BackgroundLight chain (AL) cardiac amyloidosis is associated with a poor prognosis. Diagnosing at an early stage is critical for treatment and the...
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Efficacy and utility of antifibrinolytics in pediatric spine surgery: a systematic review and network meta-analysis
Antifibrinolytics have gained increasing attention in minimizing blood loss and mitigating the risks associated with massive transfusions, including...
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A randomized, open-label, adaptive, proof-of-concept clinical trial of modulation of host thromboinflammatory response in patients with COVID-19: the DAWn-Antico study
BackgroundThe peak of the global COVID-19 pandemic has not yet been reached, and many countries face the prospect of a second wave of infections...
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Correction to: Performance of 99mTc-aprotinin scintigraphy for diagnosing light chain (AL) cardiac amyloidosis confirmed by endomyocardial biopsy
This prospective study was conducted according to the principles outlined within the Declaration of Helsinki, and approved by the Ethics Review Board...
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Activation of Plasmin in Mastitic Milk
Milk and whey samples from healthy and inflamed udder quarters of 10 Ayrshire cows were analyzed for proteolytic activity using radial caseolysis...
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Desmopressin to reduce periprocedural bleeding and transfusion: a systematic review and meta-analysis
We systematically reviewed the literature to investigate the effects of peri-procedural desmopressin in patients without known inherited bleeding...
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Significance of 11C-PIB PET/CT in cardiac amyloidosis compared with 99mTc-aprotinin scintigraphy: A pilot study
BackgroundThis study was to investigate the significance of 11 C-Pittsburgh B (PIB) PET/CT in patients with suspected cardiac amyloidosis compared...
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A new decellularized tendon scaffold for rotator cuff tears – evaluation in rabbits
BackgroundScaffolds have considerably advanced in recent years. In orthopaedic surgery, scaffolds have been used as grafts in procedures involving...
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Protease secretions by the invading blastocyst induce calcium oscillations in endometrial epithelial cells via the protease-activated receptor 2
BackgroundEarly embryo implantation is a complex phenomenon characterized by the presence of an implantation-competent blastocyst and a receptive...
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Hemostatic effects of tranexamic acid in cardiac surgical patients with antiplatelet therapy: a systematic review and meta-analysis
BackgroundThe purpose of the current study was to assess the efficacy of tranexamic acid (TXA) on reducing bleeding in cardiac surgical patients with...
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