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Pregnancy, folic acid, and antiseizure medication
BackgroundAlthough some antiseizure medications (ASMs) are teratogenic, most people with epilepsy need treatment in pregnancy. The risk of ASM...
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Antiseizure Drugs and Movement Disorders
The relationship between antiseizure drugs and movement disorders is complex and not adequately reviewed so far. Antiseizure drugs as a treatment for...
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Neurobehavioral Outcomes of Children with Antenatal Exposure to Antiseizure Medications
ObjectivesTo evaluate the effect of antiepileptic medications prescribed to mothers during pregnancy on the development and behavior of children.
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Long-term antiseizure medication use in patients after meningioma resection: identifying predictors for successful weaning and failures
ObjectiveTo define risk factors for meningioma-related seizures and predictors of successful weaning of antiseizure medications following meningioma...
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Interactions Between Direct Oral Anticoagulants (DOACs) and Antiseizure Medications: Potential Implications on DOAC Treatment
The use of direct oral anticoagulants (DOACs) is increasing because of their superior efficacy and safety compared with vitamin K antagonists....
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Thromboembolic Risks with Concurrent Direct Oral Anticoagulants and Antiseizure Medications: A Population-Based Analysis
Background and ObjectiveDrug–drug interactions between direct oral anticoagulants (DOAC) and antiseizure medications via the cytochrome P450 (CYP) or...
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Synergistic effects of vagus nerve stimulation and antiseizure medication
IntroductionVagus nerve stimulation (VNS) is an effective, non-pharmacological therapy for epileptic seizures. Until now, favorable combinations of...
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Efficacy and Tolerability of Intranasal Midazolam Administration for Antiseizure Treatment in Adults: A Systematic Review
ObjectiveThe objective of this study was to assess the efficacy and tolerability of intranasal midazolam (in-MDZ) administration for antiseizure...
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Antiseizure Medication Withdrawal in Seizure-Free Patients: What is New for the Pediatrician?
The American Academy of Neurology (AAN) has recently updated its practise advisory on antiseizure medication withdrawal. The recommendations have...
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Antiseizure Medication Interactions A Clinical Guide
This significantly revised fourth edition provides a practically orientated guide to interactions associated with antiseizure medications. It...
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Impact of timing of antiseizure medication withdrawal on seizure recurrence in glioma patients: a retrospective observational study
BackgroundWithdrawal of antiseizure medication treatment (ASM) can be considered after completion of antitumour treatment in glioma patients who no...
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Newer Antiseizure Medications and Suicidality: Analysis of the Food and Drug Administration Adverse Event Reporting System (FAERS) Database
BackgroundThe association between antiseizure medications (ASMs) and suicidality remains controversial. Analyses of additional datasets are needed to...
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Sex Differences in Adverse Effects of Antiseizure Medications in Adults with Epilepsy: A Systematic Review
BackgroundSex differences in epilepsy have been described in prevalence, seizure propensity and response to treatment. Therefore, taking into account...
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The Effect of Levetiracetam Compared with Enzyme-Inducing Antiseizure Medications on Apixaban and Rivaroxaban Peak Plasma Concentrations
Background and ObjectivePost-stroke epilepsy represents an important clinical challenge as it often requires both treatment with direct oral...
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Antiseizure medications for idiopathic generalized epilepsies: a systematic review and network meta-analysis
ObjectivesTo compare the efficacy and safety of antiseizure medications (ASMs), both as monotherapies and adjunctive therapies, for idiopathic...
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Video-EEG monitoring as a valuable tool for antiseizure medication withdrawal in patients with epilepsy: implications for clinical practice and public health policies
This letter to the editor discusses “the use of video-EEG monitoring to guide antiseizure medication (ASM) withdrawal in patients with epilepsy” [
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Efficacy and Safety of Five Broad-Spectrum Antiseizure Medications for Adjunctive Treatment of Refractory Epilepsy: A Systematic Review and Network Meta-analysis
BackgroundOverall, up to one-third of epilepsy patients have drug-resistant epilepsy. However, there was previously no meta-analysis to support the...
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Pilot study on the probability of drug-drug interactions among direct oral anticoagulants (DOACs) and antiseizure medications (ASMs): a clinical perspective
Abstract BackgroundThere is little and controversial information about changes in plasma concentrations (PCs) or clinical events during...
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Brain tumor related epilepsy: pathophysiological approaches and rational management of antiseizure medication
BackgroundBrain tumor related epilepsy (BTRE) is a common complication of cerebral tumors and its incidence is highly dependent on the type of tumor,...
