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Posterior reversible encephalopathy syndrome associated with antibiotic therapy: a case report and systematic review
Posterior reversible encephalopathy syndrome (PRES) is an acute neurological condition associated with different etiologies, including antibiotic...
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Choosing Wisely internationally – helpful recommendations for antimicrobial stewardship!
PurposeAntimicrobial resistance poses a major threat to human health globally and antibiotic overuse is a main driver of resistance. Antimicrobial...
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Lack of microbiological awareness on the ward as a key factor for inappropriate use of anti-infectives: results of a point prevalence study and user satisfaction survey in a large university hospital in Austria
PurposeAlthough diagnostic stewardship issues in clinical microbiology harbor an optimization potential for anti-infective consumption, they are only...
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The clinical impact of multiplex PCR panel diagnostics in paediatric meningitis/ encephalitis: a bicenter cohort study
PurposeIn infections of the Central Nervous System (iCNS), rapid identification of causing pathogens is crucial for survival and to avoid long-term...
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Clinical evaluation of a new technique for custom-made spacers in septic two-stage revision of total hip arthroplasties
IntroductionIn septic two-stage revision surgery, success depends on numerous factors. Key steps are the procedure of ex- and reimplantation and the...
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The predictors of fungal infections after liver transplantation and the influence of fungal infections on outcomes
The primary objective of this study was to assess the incidence, timing, risk factors of fungal infections (FIs) within 3 months after liver...
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Safety-Related Drug Withdrawals in China Between 1999 and 2021: A Systematic Investigation and Analysis
IntroductionThe Chinese National Medical Products Administration (NMPA) has emphasized proactive pharmacovigilance throughout the product life cycle...
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Castleman disease of plasma cell type accompanied with bronchiolitis obliterans: a case report and review of the literature
BackgroundCastleman disease, also known as giant lymph node hyperplasia or angiofollicular lymph node hyperplasia, is a highly heterogeneous...
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Finding a balance in reduced toxicity hematopoietic stem cell transplantation for thalassemia: role of infused CD3+ cell count and immunosuppression
We performed a retrospective analysis on 124 patients with transfusion-dependent thalassemia who were registered in the German pediatric registry for...
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Establishment of an interdisciplinary board for bone and joint infections
PurposeThe incidence of bone and joint infections is increasing while their treatment remains a challenge. Although guidelines and recommendations...
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Prophylaxis, diagnosis and therapy of infections in patients undergoing high-dose chemotherapy and autologous haematopoietic stem cell transplantation. 2020 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO)
To ensure the safety of high-dose chemotherapy and autologous stem cell transplantation (HDC/ASCT), evidence-based recommendations on infectious...
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Comprehensive analysis of omics data identifies relevant gene networks for Attention-Deficit/Hyperactivity Disorder (ADHD)
Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent neurodevelopmental disorder that results from the interaction of both genetic...
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Myxopyronin B inhibits growth of a Fidaxomicin-resistant Clostridioides difficile isolate and interferes with toxin synthesis
The anaerobic, gastrointestinal pathogen Clostridioides difficile can cause severe forms of enterocolitis which is mainly mediated by the toxins...
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A case report of fatal disseminated fungal sepsis in a patient with ARDS and extracorporeal membrane oxygenation
BackgroundWith the following report we want to present an unusual case of a patient suffering from acute respiratory distress syndrome with early...
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Map** Strategies to Assess and Increase the Validity of Published Disproportionality Signals: A Meta-Research Study
Background and AimDisproportionality analysis is traditionally used in spontaneous reporting systems to generate working hypotheses about potential...
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Pediatric pharmaceutical interventions in self-medication: a descriptive study in community pharmacies
BackgroundThe practice of self-medication is common but not without risk, especially for vulnerable populations such as the pediatric population....
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Influential factors and predictors of anti-N-methyl-D-aspartate receptor encephalitis associated with severity at admission
ObjectiveWe aimed to study the clinical characteristics and biological indicators of anti-N-methyl- D -aspartate receptor (NMDAR) encephalitis with...
