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Incorporating the Molecular Mimicry of Environmental Antigens into the Causality of Autoimmune Hepatitis
Molecular mimicry between foreign and self-antigens has been implicated as a cause of autoimmune hepatitis in experimental models and cross-reacting...
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Alloimmune hemolytic disease of the fetus and newborn: genetics, structure, and function of the commonly involved erythrocyte antigens
Hemolytic disease of the fetus and newborn (HDFN) can occur when a pregnant woman has antibody directed against an erythrocyte surface antigen...
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Identification of potential tumor antigens and immune subtypes for lung adenocarcinoma
In lung adenocarcinoma (LUAD), tumor antigens and immune phenotypes are important for cancer immunotherapy. This study aims to identify potential...
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The ABO blood group antigens in patients with oral lichenoid reaction
Evaluating the association of ABO blood group with different delayed hypersensitivity reactions, such as oral lichenoid reaction (OLR), can provide a...
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Donor/recipient Rh-mismatched allogeneic hematopoietic stem cell transplantation: transfusion strategy and allo-immunization to red blood cell antigens
In the case of donor/recipient rhesus (Rh)-incompatibility after allogeneic hematopoietic stem cell transplantation (alloHSCT), the transfusion...
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Inside-out assembly of viral antigens for the enhanced vaccination
Current attempts in vaccine delivery systems concentrate on replicating the natural dissemination of live pathogens, but neglect that pathogens...
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Identification of tumor antigens and immune subtypes of acute myeloid leukemia for mRNA vaccine development
BackgroundAcute myeloid leukemia (AML) is a highly aggressive hematological malignancy, and there has not been any significant improvement in therapy...
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The secretor status of blood group antigens in the saliva in people with oral cancers: a systematic review
BackgroundHuman ABO blood group type and the antigenic secretor status are hypothesized to associate with oral diseases including oral cancer....
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Hyporesponsiveness against donor’s ABO antigens of renal grafts after ABO-incompatible kidney transplantation
BackgroundABO antigens expressed on the red blood cells (RBCs) are not identical to those expressed on the renal endothelial cells. The...
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Protective efficacy of multiepitope vaccines constructed from common antigens of Eimeria species in chickens
Clinical avian coccidiosis is typically caused by coinfection with several Eimeria species. Recombinant protein and DNA vaccines have shown promise...
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Localization and distribution of goose astrovirus 2 antigens in different tissues at different times
Goose astrovirus 2 (GAstV-2) causes visceral gout in goslings and has resulted in significant economic losses in the goose industry of China since...
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Current advances and challenges in CAR T-Cell therapy for solid tumors: tumor-associated antigens and the tumor microenvironment
The past decade has witnessed ongoing progress in immune therapy to ameliorate human health. As an emerging technique, chimeric antigen receptor...
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Identification of tumor-associated antigens and immune subtypes of lower-grade glioma and glioblastoma for mRNA vaccine development
BackgroundmRNA became a promising therapeutic approach in many diseases. This study aimed to identify the tumor antigens specifically expressed in...
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Analysis of melanoma tumor antigens and immune subtypes for the development of mRNA vaccine
Melanoma has a high degree of malignancy and mortality. While there are some hopeful clinical trials for melanoma treatment in progress, they have...
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CAR T cells redirected against tumor-specific antigen glycoforms: can low-sugar antigens guarantee a sweet success?
Immune-based therapies have experienced a pronounced breakthrough in the past decades as they acquired multiple US Food and Drug Administration (FDA)...
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Discovery and characterization of tumor antigens in hepatocellular carcinoma for mRNA vaccine development
BackgroundmRNA vaccines are emerging as new targets for cancer immunotherapy. However, the potential tumor antigens for mRNA vaccine design in...
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The challenge of selecting tumor antigens for chimeric antigen receptor T-cell therapy in ovarian cancer
Ovarian cancer (OC) is one of the most common cancers in women, with a high mortality rate and very few available and effective treatments. Evidence...
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Expression of four cancer-testis antigens in TNBC indicating potential universal immunotherapeutic targets
ObjectiveImmunotherapy is an attractive treatment for breast cancer. Cancer-testis antigens (CTAs) are potential targets for immunotherapy for their...
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Lupus-like membranous nephropathy during the postpartum period expressing glomerular antigens exostosin 1/exostosin 2 and phospholipase A2 receptor: a case report
Recently, several target antigens of membranous nephropathy (MN), such as phospholipase A2 receptor (PLA2R) and exostosin 1/exostosin 2 (EXT1/2),...
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Coexpression of natural killer cell antigens by T-cell large granular lymphocytes in hydroa vacciniforme lymphoproliferative disorder and the involvement of Vδ1 + epithelial-type γδT cells
Hydroa vacciniforme lymphoproliferative disorder (HV-LPD) is a cutaneous variant of chronic active Epstein–Barr virus disease. We examined the...
