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Chemical composition and antifungal activity of Teucrium Leucocladum Boiss. essential oils growing in Egypt using two different techniques
BackgroundTeucrium Leucocladum Boiss. (TL) (family Lamiaceae), indigenous to Sinai, Egypt, and Mediterranean region, is considered a rich source of...
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Elucidating the antifungal activity and mechanism of action of bioactive phytochemicals against fungal dermatitis isolates
Dermatophytosis has been the most common cause of superficial fungal infections which invade the keratinized tissues of body such as nail, hair, and...
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Exploring the Potential of Farnesol as a Novel Antifungal Drug and Related Challenges
Purpose of ReviewFarnesol (FOH) is a quorum-sensing molecule with potential as an antifungal drug. Given the growing concern about fungal drug...
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Antifungal Stewardship Interventions in Patients with Hematologic Malignancies
Purpose of ReviewAntifungal stewardship has been recognized as a significant component of any antimicrobial stewardship program. In this article, we...
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Antifungal therapy for the treatment of CNS infections
Purpose of reviewA review of existing and emerging therapies for the treatment of fungal infections of the CNS is presented, highlighting more recent...
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Candida albicans and Antifungal Peptides
Candida albicans , a ubiquitous opportunistic fungal pathogen, plays a pivotal role in human health and disease. As a commensal organism, it normally...
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Antiviral activity and mechanism of the antifungal drug, anidulafungin, suggesting its potential to promote treatment of viral diseases
BackgroundThe severe fever with thrombocytopenia syndrome disease (SFTS), caused by the novel tick-borne SFTS virus (SFTSV), was listed among the top...
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Antifungal activity of three different varieties of Capsicum annuum against clinical isolates of Candida species
ObjectiveAcquired resistance to antifungal agents is rising among Candida species. Herbal extracts including Capsicum annum extracts have biological...
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Antifungal Dosing in Critically Ill Patients on Extracorporeal Membrane Oxygenation
Extracorporeal membrane oxygenation (ECMO) is an established advanced life support system, providing temporary cardiac and/or respiratory support in...
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Pharmacokinetic and pharmacodynamic considerations for antifungal therapy optimisation in the treatment of intra-abdominal candidiasis
Intra-abdominal candidiasis (IAC) is one of the most common of invasive candidiasis observed in critically ill patients. It is associated with high...
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Role of Antifungal Susceptibility Tests in the Treatment of Vulvovaginal Candidiasis
Purpose of ReviewThe increased prevalence of antifungal drug resistance associated with common vaginal pathogen C. albicans as well as non- albicans...
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Characterization of tea (Camellia sinensis L.) flower extract and insights into its antifungal susceptibilities of Aspergillus flavus
BackgroundTea ( Camellia sinensis L.) flowers will compete with tea leaves in nutrition and are abandoned as an undesirable by-product. In this...
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Preclinical Pharmacokinetic/Pharmacodynamic Studies and Clinical Trials in the Drug Development Process of EMA-Approved Antifungal Agents: A Review
Antifungal drug development is essential as invasive fungal disease is still associated with a very high mortality rate and the emergence of...
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Activity of antifungal drugs and Brazilian red and green propolis extracted with different methodologies against oral isolates of Candida spp.
BackgroundOral candidiasis is an opportunistic disease caused by fungi of the Candida genus. The occurrence of Candida spp. resistance to the...
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Antifungal Resistance and the Role of New Therapeutic Agents
Purpose of ReviewAdvances in health care over time have led to an evolution in the epidemiology of invasive fungal infections. There is an increasing...
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A case of Lomentospora prolificans endophthalmitis treated with the novel antifungal agent Olorofim
PurposeTo report a case of endogenous Lomentospora prolificans endophthalmitis treated with the novel antifungal agent Olorofim.
Case report ...
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Antifungal Prophylaxis in the Era of Targeted Chemotherapy for Acute Myelogenous Leukemia
Purpose of ReviewThis review will provide an overview of the potential drug-drug interactions (DDIs) that may occur when using small-molecule kinase...
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Recent Advances and Future Perspectives in Mitigating Invasive Antifungal-Resistant Pathogen Aspergillus fumigatus in Africa
Purpose of ReviewAzole resistance in Aspergillus fumigatus is an emerging public health issue with global distribution and has been linked to use in...
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Chemical profiling of antifungal Dicerocaryum senecioides and Diospyros mespiliformis extracts using TLC-p-iodonitrotetrazolium violet assay and GC–MS/MS
BackgroundDespite the availability of conventional medication for fungal skin diseases, dermatophytic infections are now a major crisis in the whole...
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