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Liver enzyme inducing anticonvulsant drug use is associated with prevalent vertebral fracture
SummaryAmong those who use of liver-enzyme inducing anticonvulsant medication for more than 2 years, 27% have a prevalent vertebral fracture on...
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Gut-Brain-axis: effect of basil oil on the gut microbiota and its contribution to the anticonvulsant properties
BackgroundEpilepsy is a chronic neurological condition that disrupts the normal functioning of the brain and it is characterized by seizures....
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Olivetolic acid, a cannabinoid precursor in Cannabis sativa, but not CBGA methyl ester exhibits a modest anticonvulsant effect in a mouse model of Dravet syndrome
ObjectiveCannabigerolic acid (CBGA), a precursor cannabinoid in Cannabis sativa , has recently been found to have anticonvulsant properties in the Scn1a...
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Vitamin D Status in Children on Anticonvulsant Therapy
ObjectiveTo assess vitamin D status of children on long-term anticonvulsants, including the less studied widely used levetiracetam, and the potential...
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Anticonvulsant use and bone health in a population-based study of men and women: cross-sectional data from the Geelong Osteoporosis Study
BackgroundAnticonvulsant use has been linked to bone deficits in specific patient populations. We studied the association between anticonvulsant use...
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Differential ketogenic diet-induced shift in CSF lipid/carbohydrate metabolome of pediatric epilepsy patients with optimal vs. no anticonvulsant response: a pilot study
BackgroundThe low carbohydrate, high fat ketogenic diet can be an effective anticonvulsant treatment in some pediatric patients with...
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Knowledge of pharmacy workers on antihypertensive and anticonvulsant drugs for managing pre-eclampsia and eclampsia in Bangladesh
BackgroundPharmacy workers in Bangladesh play an important role in managing pregnancy complications by dispensing, counselling and selling drugs to...
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The Toxicity of Newer and Lesser-Known Anticonvulsant Drugs
Purpose of ReviewThis review describes newer and lesser-known anticonvulsant drugs. Due to increased diagnostic accuracy of seizure disorder...
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Patterns of prophylactic anticonvulsant use in spontaneous intracerebral and subarachnoid hemorrhage: results of a practitioner survey
BackgroundThe use of prophylactic anti-seizure medications (ASMs) in the management of patients with spontaneous intracerebral hemorrhage (sICH) and...
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How do pediatric patients perceive adverse drug events of anticonvulsant drugs? A survey
Anticonvulsant drugs have a high risk of adverse drug events. Little is known about the perception of those events by pediatric patients. We...
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The standardized extract of Centella asiatica L. Urb attenuates the convulsant effect induced by lithium/pilocarpine without affecting biochemical and haematological parameters in rats
BackgroundStatus epilepticus (SE) is a type of epileptic activity characterized by a failure of the inhibitory mechanisms that limit seizures, which...
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An Update on Stiripentol Mechanisms of Action: A Narrative Review
Stiripentol (Diacomit ® ) (STP) is an orally active antiseizure medication (ASM) indicated as adjunctive therapy, for the treatment of seizures...
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Comparison between Phenobarbitone and Levetiracetam as the initial anticonvulsant in preterm neonatal seizures — a pilot randomized control trial in develo** country setup
This study aimed to compare the efficacy and safety of intravenous Levetiracetam and Phenobarbitone in the treatment of seizures in preterm neonates....
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Medicinal plants utilized in the management of epilepsy in Ethiopia: ethnobotany, pharmacology and phytochemistry
Epilepsy is a common central nervous system (CNS) disorder that affects 50 million people worldwide. Patients with status epilepticus (SE) suffer...
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Effects of berberine on pentylenetetrazole-induced seizures during estrus cycle in rats
Catamenial epilepsy is one of the central brain-related disorders associated with a menstrual cycle in some epileptic women. This study aimed to...
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Efficacy of anticonvulsant ethosuximide for major depressive disorder: a randomized, placebo-control clinical trial
Results of a preclinical study suggested that the anticonvulsant drug ethosuximide may elicit ketamine-like rapid-acting antidepressant actions. We...
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Epilepsy Management in Transgender and Gender Diverse People
Purpose of reviewThe goal of this review is to outline important topics in epilepsy management for transgender and gender diverse individuals....