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Variables associated with antibiotic treatment tolerance in patients with Mycobacterium avium complex pulmonary disease
BackgroundTreatment of Mycobacterium avium complex pulmonary disease (MAC-PD) involves prolonged courses of multiple antibiotics that are variably...
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Exploring the Preferences of the Australian Public for Antibiotic Treatments: A Discrete Choice Experiment
ObjectivesIdentify Australian public preferences for antibiotic treatments in the context of antibiotic stewardship.
MethodsA discrete choice...
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How Streptococcus suis escapes antibiotic treatments
Streptococcus suis is a zoonotic agent that causes sepsis and meningitis in pigs and humans. S. suis infections are responsible for large economic...
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Family doctors’ roles and perceptions on antibiotic consumption and antibiotic resistance in Romania: a qualitative study
BackgroundAntimicrobial resistance (AMR) is a major global health issue, bringing significant health burden and costs to societies. Increased...
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A quality improvement initiative standardizing the antibiotic treatment and feeding practices in patients with medical necrotizing enterocolitis
ObjectiveEvaluate the impact of a multidisciplinary guideline standardizing antibiotic duration and enteral feeding practices following medical...
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Oral antibiotic prophylaxis for infection in patients with vascular anomalies receiving sirolimus treatment: a multicenter retrospective study
ObjectivesPatients with vascular anomalies (VAs) who receive oral sirolimus may be at high risk of infectious complications. Antibiotic prophylaxis...
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Antibacterial Alternatives to a Dying Antibiotic Pipeline
Purpose of reviewThis study summarized the current problems and potential solutions related to the rise of multidrug-resistant bacteria, the lack of...
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In-hospital antibiotic use for severe chronic obstructive pulmonary disease exacerbations: a retrospective observational study
BackgroundThe use of antibiotics in mild to severe acute exacerbations of chronic obstructive pulmonary disease (COPD) remains controversial.
...
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Does diagnostic uncertainty increase antibiotic prescribing in primary care?
This study aimed to determine the association between factors relevant to diagnostic uncertainty and physicians’ antibiotic-prescribing behaviour in...
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Variability in antibiotic duration for necrotizing enterocolitis and outcomes in a large multicenter cohort
ObjectivesTo evaluate variability in antibiotic duration for necrotizing enterocolitis (NEC) and associated clinical outcomes.
Study design ...
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Personalized antibiograms for machine learning driven antibiotic selection
BackgroundThe Centers for Disease Control and Prevention identify antibiotic prescribing stewardship as the most important action to combat...
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Pharmacokinetics, efficacy and tolerance of cefoxitin in the treatment of cefoxitin-susceptible extended-spectrum beta-lactamase producing Enterobacterales infections in critically ill patients: a retrospective single-center study
BackgroundCefoxitin is active against some extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-PE), but has not been evaluated so far...
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Identification of ClpB, a molecular chaperone involved in the stress tolerance and virulence of Streptococcus agalactiae
Bacterial ClpB is an ATP-dependent disaggregate that belongs to the Hsp100/Clp family and facilitates bacterial survival under hostile environmental...
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Antibiotic-loaded calcium sulfate in clinical treatment of chronic osteomyelitis: a systematic review and meta-analysis
BackgroundPresent work was aimed to gather accessible evidence on the eradication rates and related postoperative complications of antibiotic-loaded...
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Serological and Antibiotic Resistance Patterns As Well As Molecular Characterization of Vibrio parahaemolyticus Isolated from Coastal Waters in the Eastern Province of Saudi Arabia
Vibrio parahaemolyticus belongs to the halophilic genus of Vibrionaceae family that inhabits coastal and marine environments and is a major...
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Context and general practitioner decision-making - a sco** review of contextual influence on antibiotic prescribing
BackgroundHow contextual factors may influence GP decisions in real life practice is poorly understood. The authors have undertaken a sco** review...
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Antimicrobial resistance patterns and genetic elements associated with the antibiotic resistance of Helicobacter pylori strains from Shanghai
BackgroundShanghai, in east China, has one of the world’s highest burdens of Helicobacter pylori infection. While multidrug regimens can effectively...
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Impact of Radiography on Antibiotic Prescribing Practices in Patients with Acute Decompensated Heart Failure
Chest radiography findings can be similar in acute decompensated heart failure (ADHF) and pneumonia. Prescriber discretion is needed to avoid...
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Long-term, low-dose macrolide antibiotic treatment in pediatric chronic airway diseases
AbstractMacrolide antibiotics are one of the most commonly used broad-spectrum antibiotics. They have an inhibitory effect on a variety of...
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Effect of an exclusive human milk diet on feeding tolerance in preterm infants
ObjectiveTo compare the time to full enteral feeds in preterm infants fed exclusive human milk (EHM) - mother’s own milk (MOM) fortified with human...
