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  1. Enhanced anti-cancer effect of artemisinin- and curcumin-loaded niosomal nanoparticles against human colon cancer cells

    Colorectal cancer (CRC) is the third broadly identified cancer in the world. The ineffectiveness of colorectal cancer treatment is redundantly...

    Akram Firouzi Amandi, Elham Jokar, ... Babak Nejati in Medical Oncology
    Article 08 May 2023
  2. Advanced nano-therapeutic delivery of metformin: potential anti-cancer effect against human colon cancer cells through inhibition of GPR75 expression

    The high incidence rate coupled with significant mortality makes colorectal cancer one of the most prevalent and devastating cancers worldwide....

    Fatemeh Ghorbanzadeh, Davoud Jafari-Gharabaghlou, ... Nosratollah Zarghami in Medical Oncology
    Article 29 July 2023
  3. Sodium orthovanadate exhibits anti-angiogenic, antiapoptotic and blood glucose-lowering effect on colon cancer associated with diabetes

    Background

    The presence of type 2 diabetes mellitus increases the risk of develo** the colon cancer. The main objective of this study was to...

    Kruti Patel, Vivek Bora, Bhoomika Patel in Cancer Chemotherapy and Pharmacology
    Article 27 September 2023
  4. In vitro study on anti-proliferative and anti-cancer activity of picrosides in triple-negative breast cancer

    Picrorhiza kurroa, an “Indian gentian,” a known Himalayan medicinal herb with rich source of phytochemicals like picrosides I, II, and other...

    Deepika Soni, Divya Wahi, Saurabh Verma in Medical Oncology
    Article 08 May 2024
  5. A review on the research progress of traditional Chinese medicine with anti-cancer effect targeting ferroptosis

    Ferroptosis is a non-apoptotic form of regulated cell death characterized by iron-dependent lipid peroxidation. It can be triggered by various...

    Longyan Wang, Huiming Huang, ... Zhongdong Hu in Chinese Medicine
    Article Open access 13 October 2023
  6. The effect of the anti-leukemia inhibitory factor on the immune system in the Balb/c mice bearing breast cancer induced with 4T1 cells

    Background

    Breast cancer is one of the most common cancers. Leukemia inhibitory factor (LIF) is considered as one of the effective factors in the...

    Abolfazl Yavari, Fateme Zare, ... Mohammad Taher Tahoori in European Journal of Medical Research
    Article Open access 01 July 2023
  7. Anti-cancer effect of palmatine through inhibition of the PI3K/AKT pathway in canine mammary gland tumor CMT-U27 cells

    Canine mammary gland tumors (CMTs) are the most common and lethal cancers in female dogs. Dysregulated phosphoinositide 3-kinases (PI3K)/AKT pathway...

    Min-Jae Yoo, Jawun Choi, ... Jae-Won Seol in BMC Veterinary Research
    Article Open access 25 October 2023
  8. Anti-cancer activity of Moringa oleifera Lam. seed oil on oral cancer

    Background

    Despite recent advances in the diagnosis and treatment of oral cancer, relative survival rates have not changed significantly. Moringa...

    Moumita Das, Jatindra Nath Mohanty, ... Ruchi Bhuyan in Beni-Suef University Journal of Basic and Applied Sciences
    Article Open access 15 March 2024
  9. Neuro-ophthalmic complications of modern anti-cancer drugs

    Purpose

    Targeted cancer therapies have been responsible for a dramatic shift in treatment strategies for cancer, and the number of drugs, classes, and...

    Joshua A. Oskam, Helen V. Danesh-Meyer in Graefe's Archive for Clinical and Experimental Ophthalmology
    Article Open access 12 February 2024
  10. Anti-microbial and anti-cancer efficacy of acetone extract of Rosa chinensis against resistant strain and lung cancer cell line

    Background

    Screening of herbal plants for various therapeutic properties is the hour as it shows promising activity. Scientific evidence of the...

    Kalaivani Madhavaram Kuppusamy, Sivakumar Selvaraj, ... Krishnamoorthy Gunasekaran in BMC Complementary Medicine and Therapies
    Article Open access 10 November 2023
  11. Anti-cancer potential of casein and its derivatives: novel strategies for cancer treatment

    Cancer is one of the leading causes of death worldwide, with over 10 million fatalities annually. While tumors can be surgically removed and treated...

    Daniel Romero-Trejo, Itzen Aguiñiga-Sanchez, ... Edelmiro Santiago-Osorio in Medical Oncology
    Article Open access 11 July 2024
  12. Anti-cancer effects of DHP107 on canine mammary gland cancer examined through in-vitro and in-vivo mouse xenograft models

    Background

    Canine mammary gland cancer (CMGC) is a common neoplasm in intact bitches. However, the benefit of adjuvant chemotherapy is unclear. The...

    Hyung-Kyu Chae, Ye-In Oh, ... Hwa-Young Youn in BMC Veterinary Research
    Article Open access 03 January 2024
  13. Identification of Fangjihuangqi Decoction as a late-stage autophagy inhibitor with an adjuvant anti-tumor effect against non-small cell lung cancer

    Background

    Clinically, although chemotherapy is one of the most commonly used methods of treating tumors, chemotherapeutic drugs can induce autophagic...

    Qiugu Chen, Yuan Liao, ... Shan Hu in Chinese Medicine
    Article Open access 07 June 2023
  14. Genipin’s potential as an anti-cancer agent: from phytochemical origins to clinical prospects

    This comprehensive review delves into the multifaceted aspects of genipin, a bioactive compound derived from medicinal plants, focusing on its...

    Lapava Natallia, Aida Dama, ... Javad Sharifi-Rad in Medical Oncology
    Article 25 June 2024
  15. Co-targeting CD47 and VEGF elicited potent anti-tumor effects in gastric cancer

    Background

    CD47, serving as an intrinsic immune checkpoint, has demonstrated efficacy as an anti-tumor target in hematologic malignancies....

    Kaiqi Zhang, Yuan Xu, ... Kai Yin in Cancer Immunology, Immunotherapy
    Article Open access 27 March 2024
  16. The effect of radioactive iodine therapy on anti-Müllerian hormone changes in women with thyroid cancer at reproductive age: a prospective study

    Background

    Thyroid cancer is one of the common cancers that, depending on the need for treatment, patients are treated with radioactive iodine after...

    Ali Hosseini, Zohreh Lavasani in Middle East Fertility Society Journal
    Article Open access 23 September 2023
  17. Immunohistochemical analysis of B7-H3 expression in patients with lung cancer following various anti-cancer treatments

    B7 homolog 3 protein (B7-H3), an immune checkpoint molecule belonging to the B7 family, has been studied as a target for the development of...

    Shota Omori, Koji Muramatsu, ... Toshiaki Takahashi in Investigational New Drugs
    Article 10 April 2023
  18. Development of pharmacological immunoregulatory anti-cancer therapeutics: current mechanistic studies and clinical opportunities

    Immunotherapy represented by anti-PD-(L)1 and anti-CTLA-4 inhibitors has revolutionized cancer treatment, but challenges related to resistance and...

    Nanhao Yin, **ntong Li, ... Jianxin Xue in Signal Transduction and Targeted Therapy
    Article Open access 22 May 2024
  19. Anti-cancer activity of ultra-short single-stranded polydeoxyribonucleotides

    One of the features that differentiate cancer cells is their increased proliferation rate, which creates an opportunity for general anti-tumor...

    Alexander S. Vedenkin, Sergey V. Stovbun, ... Dmitry A. Kuznetsov in Investigational New Drugs
    Article 07 February 2023
  20. A review of anti-tumour effects of Ganoderma lucidum in gastrointestinal cancer

    Gastrointestinal (GI) cancer is the most common cancer in the world and one of the main causes of cancer-related death. Clinically, surgical excision...

    Ting Ye, Yang Ge, ... Bin Liu in Chinese Medicine
    Article Open access 28 August 2023
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