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Biomarkers and signaling pathways of diabetic nephropathy and peripheral neuropathy: possible therapeutic intervention of rutin and quercetin
Diabetic nephropathy and peripheral neuropathy are the two main complications of chronic diabetes that contribute to high morbidity and mortality....
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Flavonoids on diabetic nephropathy: advances and therapeutic opportunities
With the advances in biomedical technologies, natural products have attracted substantial public attention in the area of drug discovery. Flavonoids...
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Chronic pain following elective surgery under general anesthesia in older adults
BackgroundThe purpose of this study was to investigate the association between age and chronic postsurgical pain (CPSP) in patients who underwent...
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Induction of anxiolytic, antidepressant and analgesic effects by Shiff base of (E)-3-(1H-imidazol-4-yl)-2-((2-oxoindolin-3-ylidene)amino)propanoic acid derivatives in diabetic rats
Diabetes mellitus is a metabolic disorder with several psychological problems such as anxiety, depression, and pain sense. This study aimed to...
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Evaluation of nephroprotective and cytotoxic effect of ethanolic extract of Mikania scandens leaves by using alloxan-induced diabetic nephropathy mice
BackgroundDiabetic is one of the fundamental persuasive of diabetic nephropathy and significantly sparks off kidney diseases and end stage renal...
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Delayed remnant kidney function recovery is less observed in living donors who receive an analgesic, intrathecal morphine block in laparoscopic nephrectomy for kidney transplantation: a propensity score-matched analysis
BackgroundThis study analyzed remnant kidney function recovery in living donors after laparoscopic nephrectomy to establish a risk stratification...
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Artemisia vulgaris Linn: an updated review on its multiple biological activities
BackgroundArtemisia vulgaris Linn, an annual herb, is also known as Mugwort or Wormwood in English, Nagadouna in Hindi, Mashibattiri, or Machipatri...
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Analgesic Efficacy, Practicality and Safety of Inhaled Methoxyflurane Versus Standard Analgesic Treatment for Acute Trauma Pain in the Emergency Setting: A Randomised, Open-Label, Active-Controlled, Multicentre Trial in Italy (MEDITA)
IntroductionInhaled low-dose methoxyflurane is approved in Europe for emergency relief of moderate-to-severe trauma-related pain in adults, but data...
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Iliopsoas abscess in patients receiving hemodialysis: a case series and a literature survey
BackgroundIliopsoas abscess is a relatively rare but serious infectious disease. Infectious disease is one of the major causes of death among...
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Recurrent diabetic myonecrosis in an African American woman with long-standing uncontrolled type 2 diabetes: a case report
BackgroundDiabetic myonecrosis, also called diabetic muscle infarction, is an uncommon complication of uncontrolled diabetes mellitus and is...
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The 2023 WSES guidelines on the management of trauma in elderly and frail patients
BackgroundThe trauma mortality rate is higher in the elderly compared with younger patients. Ageing is associated with physiological changes in...
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Medicinal Effects, Phytochemistry, Pharmacology of Euphorbia prostrata and Promising Molecular Mechanisms
Euphorbiaceae is a large family of dicotyledonous angiosperms with diverse genera including Euphorbia prostrata ( E. prostrata ). Current research has...
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The prevalence of Fabry disease in a Turkish population with chronic kidney patients
Background and objectivesFabry disease (FD) is an X-linked lysosomal storage disease with various clinical symptoms due to a deficiency of an enzyme...
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Neuromodulation Interventions for the Treatment of Painful Diabetic Neuropathy: a Systematic Review
Purpose of ReviewPainful diabetic neuropathy (PDN) is a prevalent and debilitating condition, characterized by severe burning, tingling, and...
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Efficacy and safety of removing peritoneal dialysis catheters using the pull technique
PurposeTo study the efficacy and safety of peritoneal dialysis (PD) catheter removal using the pull technique.
MethodsWe conducted a retrospective...
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The Evaluation and Management of Visceral Complications in Radiation Fibrosis Syndrome Part 2
AbstractContemporary cancer treatment involves multi-modal therapeutics, and external beam ionizing radiation is utilized in approximately 50% of...
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Hospital-based screening to detect patients with cadmium nephropathy in cadmium-polluted areas in Japan
BackgroundIn health examinations for local inhabitants in cadmium-polluted areas, only healthy people are investigated, suggesting that patients with...
