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Alveolar capillary dysplasia with misalignment of pulmonary veins in a premature newborn: the role of lung ultrasound
BackgroundAlveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is a lethal neonatal lung disorder characterized by the...
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Genotype–phenotype correlation in two Polish neonates with alveolar capillary dysplasia
BackgroundAlveolar capillary dysplasia (ACD) is a rare cause of severe pulmonary hypertension and respiratory failure in neonates. The onset of ACD...
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Biophysical properties of alveolar surfactant in drever dogs with hunting associated pulmonary edema
BackgroundA syndrome of acute non-cardiogenic pulmonary edema associated with hunting is prevalent in the drever breed, but etiology of this syndrome...
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Combined gestational age and serum fucose for early prediction of risk for bronchopulmonary dysplasia in premature infants
ObjectiveAs the predominant complication in preterm infants, Bronchopulmonary Dysplasia (BPD) necessitates accurate identification of infants at risk...
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Leveraging transcriptomics to develop bronchopulmonary dysplasia endotypes: a concept paper
ImpactBronchopulmonary dysplasia has multiple definitions that are currently based on phenotypic characteristics. Using an unsupervised machine...
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A familial case of alveolar capillary dysplasia with misalignment of the pulmonary veins: the clinicopathological features and unusual glomeruloid endothelial proliferation
BackgroundAlveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is a rare disorder of pulmonary vascular abnormality with...
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Fast detection of FOXF1 variants in patients with alveolar capillary dysplasia with misalignment of pulmonary veins using targeted sequencing
BackgroundAlveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is a lethal congenital lung disorder associated with...
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Perinatal origins of bronchopulmonary dysplasia—deciphering normal and impaired lung development cell by cell
Bronchopulmonary dysplasia (BPD) is a multifactorial disease occurring as a consequence of premature birth, as well as antenatal and postnatal injury...
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Pilot dose-ranging of rhIGF-1/rhIGFBP-3 in a preterm lamb model of evolving bronchopulmonary dysplasia
BackgroundLow levels of insulin-like growth factor-1 (IGF-1) protein in preterm human infants are associated with bronchopulmonary dysplasia (BPD)....
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Right ventricle speckle tracking in bronchopulmonary dysplasia: one-year follow-up
BackgroundBronchopulmonary dysplasia (BPD) is still a major concern in preterm infants and adequate screening methods for secondary right ventricle...
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Patho-mechanisms of the origins of bronchopulmonary dysplasia
Bronchopulmonary dysplasia (BPD) continues to be one of the most common complications of prematurity, despite significant advancement in neonatology...
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A comprehensive study on machine learning models combining with oversampling for bronchopulmonary dysplasia-associated pulmonary hypertension in very preterm infants
BackgroundBronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) remains a devastating clinical complication seriously affecting the...
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Two autopsy cases of siblings with alveolar capillary dysplasia: clinical and post-mortem issues
Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is a rare but fatal lung disorder, which causes persistent pulmonary...
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Premature infants born <28 weeks with acute kidney injury have increased bronchopulmonary dysplasia rates
BackgroundDespite a growing understanding of bronchopulmonary dysplasia (BPD) and advances in management, BPD rates remain stable. There is mounting...
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Physiological dead space and alveolar ventilation in ventilated infants
BackgroundDead space is the volume not taking part in gas exchange and, if increased, could affect alveolar ventilation if there is too low a...
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Angiopoietin-1 protects against endotoxin-induced neonatal lung injury and alveolar simplification in mice
BackgroundSepsis in premature newborns is a risk factor for bronchopulmonary dysplasia (BPD), but underlying mechanisms of lung injury remain...
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Platelet is the early predictor of bronchopulmonary dysplasia in very premature infants: an observational cohort study
BackgroundA previous study showed that the lungs are involved in the biogenesis of platelets (PLTs). Thus, the present study aimed to investigate the...
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Diffuse alveolar hemorrhage in children with trisomy 21
BackgroundRespiratory conditions are the leading cause of hospitalization and death in children with Trisomy 21 (T21). Diffuse alveolar hemorrhage...
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Bronchopulmonary dysplasia and wnt pathway-associated single nucleotide polymorphisms
AimGenetic variants contribute to the pathogenesis of bronchopulmonary dysplasia (BPD). The aim of this study is to evaluate the association of 45...
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Quercetin for inhibition of inflammatory responses and oxidative stress in lung injury model: a systematic review and meta-analysis
Acute lung injury (ALI) is a life-threatening clinical syndrome with high morbidity and mortality. The main pathological features of ALI are...