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Non-altered incretin secretion in women with impaired fasting plasma glucose in the early stage of pregnancy: a case control study
BackgroundsGlucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) may be involved in pathogenesis of gestational diabetes...
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Pancreatic fatty replacement as risk marker for altered glucose metabolism and cardiac iron and complications in thalassemia major
ObjectivesThis multicenter study assessed the extent of pancreatic fatty replacement and its correlation with demographics, iron overload, glucose...
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Altered expression of long noncoding RNA MEG3 in the offspring of gestational diabetes mellitus induces impaired glucose tolerance in adulthood
AimGestational diabetes mellitus (GDM) affects a significant number of women worldwide and has been associated with lifelong health consequences for...
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Hepatic glucose metabolism in the steatotic liver
The liver is central in regulating glucose homeostasis, being the major contributor to endogenous glucose production and the greatest reserve of...
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The addition of mycoprotein to a mixed-meal impacts postprandial glucose kinetics without altering blood glucose concentrations: a randomised controlled trial
BackgroundMycoprotein is a high-fibre food previously shown to reduce postprandial glucose concentrations when ingested within a mixed-meal. We...
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Continuous glucose monitoring-derived time in range and CV are associated with altered tissue characteristics of the carotid artery wall in people with type 2 diabetes
Aims/hypothesisPrevious studies have suggested that glucose variability may accelerate atherosclerosis progression in people with type 2 diabetes....
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Intermittent scanning continuous glucose monitoring is safe and useful in postsurgical glucose monitoring after pancreatoduodenectomy
AimsIntermittently scanned continuous glucose monitoring (isCGM) systems have not been thoroughly evaluated during in-hospital stay, and there are...
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Antipsychotics impair regulation of glucose metabolism by central glucose
Hypothalamic detection of elevated circulating glucose triggers suppression of endogenous glucose production (EGP) to maintain glucose homeostasis....
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Stimulating cardiac glucose oxidation lessens the severity of heart failure in aged female mice
Heart failure is a prevalent disease worldwide. While it is well accepted that heart failure involves changes in myocardial energetics, what...
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Obesity risk is associated with altered cerebral glucose metabolism and decreased μ-opioid and CB1 receptor availability
BackgroundObesity is a pressing public health concern worldwide. Novel pharmacological means are urgently needed to combat the increase of obesity...
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Association between non-dip** blood pressure pattern and different glucometabolic profile during oral glucose tolerance test
It is known that, a not physiological blood pressure (BP) circadian pattern has been associated with increased risk of organ damage and...
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Recovery of intracellular glucose uptake in T cells during partial remission of type 1 diabetes
Aims/hypothesisNotwithstanding the irreversible beta cell failure seen in type 1 diabetes, some individuals may experience a special phase named...
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Hyperglucagonaemia in diabetes: altered amino acid metabolism triggers mTORC1 activation, which drives glucagon production
Aim/hypothesisHyperglycaemia is associated with alpha cell dysfunction, leading to dysregulated glucagon secretion in type 1 and type 2 diabetes;...
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Diet-induced insulin resistance altered cardiac GLUT4 and FATP/CD36 expression in rats
BackgroundAltered substrate transport protein expression is central to the effect of insulin resistance on cardiac metabolism. The present study was...
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Glucose metabolism disorder: a potential accomplice of SARS-CoV-2
Globally, 265,713,467 confirmed cases of SARS-CoV-2 (CoV-2), including 5,260,888 deaths, have been reported by the WHO. It is important to study the...
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Differential contribution of alpha and beta cell dysfunction to impaired fasting glucose and impaired glucose tolerance
Aims/hypothesisPeople with isolated impaired fasting glucose (IFG) have normal beta cell function. We hypothesised that an increased glucose...
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First-trimester HbA1c in relation to plasma glucose concentrations in an oral glucose tolerance test at 12 to 16 weeks’ gestation—a population-based study
BackgroundEarly-onset GDM often requires pharmacological treatment and is associated with adverse perinatal outcomes, but data is insufficient...
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Serum HMGB1 levels are independently associated with glucose clamp-derived measures of insulin resistance in women with PCOS
PurposePCOS is associated with low grade inflammation which could play a role in insulin resistance and ovarian dysfunction. Preliminary findings...
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Glucose tolerance and markers of myocardial injury after an acute coronary syndrome: predictive role of the 1-h plus 2-h plasma glucose at the oral glucose tolerance test
ObjectiveImpaired glucose tolerance (IGT) has been related to adverse cardiovascular outcomes. We investigated the added value of 1-h plasma glucose...
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FDG imaging with long-axial field-of-view PET/CT in patients with high blood glucose—a matched pair analysis
PurposeHigh blood glucose (hBG) in patients undergoing [ 18 F]FDG PET/CT scans often results in rescheduling the examination, which may lead to...
