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Reference values for urinary protein, albumin, beta 2-microglobulin, and the alpha 1-microglobulin-to-creatinine ratio in Japanese children
BackgroundThe importance of the ratio of creatinine to urinary protein, albumin, and low-molecular weight protein as a urinary marker in chronic...
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Urine alpha 1-microglobulin-to-creatinine ratio and beta 2-microglobulin-to-creatinine ratio for detecting CAKUT with kidney dysfunction in children
BackgroundThe leading cause of advanced chronic kidney disease (CKD) in children is congenital anomalies of the kidney and urinary tract (CAKUT)....
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Role of Alpha-2-Microglobulin in the Treatment of Osteoarthritic Knee Pain: a Brief Review of the Literature
Purpose of ReviewChronic knee pain remains a debilitating condition that remains difficult to manage. The purpose of this review, therefore, is to...
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Removal performance of pre- and post-dilution online hemodiafiltration using identical hemodiafilters in the same patients
Online hemodiafiltration (OHDF) for renal replacement therapy has two modes: pre- (pre-OHDF) and post-dilution OHDF (post-OHDF). To elucidate the...
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Correction to: Role of Alpha-2-Microglobulin in the Treatment of Osteoarthritic Knee Pain: a Brief Review of the Literature
The original publication listed author Alan Kaye as “A. Kaye,” but his name should read “A.D. Kaye.” The correct author name is presented in this...
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Epiregulin: A new prognostic molecule in non-Hodgkin lymphoma
BackgroundEpiregulin is a molecule that plays a role in cell proliferation, tumor development, inflammation, and angiogenesis in malignant diseases.
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Serum alpha 1 antitrypsin potent act as an early diagnostic biomarker for cardiac amyloidosis
Cardiac amyloidosis is a refractory cardiomyopathy with a poor prognosis and lacks effective treatments. N-terminal pro-brain natriuretic peptide...
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FAM72D in plasma cell myeloma: a friend or enemy
BackgroundPlasma cell neoplasm is characterized by complex genetic and prognostic heterogeneity. FAM72D, a gene located on chromosome 1, and the...
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Medium cut-off dialyzer for middle molecular uremic toxins in AKI and chronic dialysis
Uremic toxins accumulate in patients affected by renal failure and can deposit in different organs, including the kidneys and heart. Given their...
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Urinary biomarkers associated with acute kidney injury in pediatric mechanical circulatory support patients
BackgroundIn patients requiring mechanical circulatory support (MCS), the incidence of acute kidney injury (AKI) is between 37 and 63%. In this...
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Autonomic function and inflammation in pregnant women participating in a randomized controlled study of Mindfulness Based Childbirth and Parenting
BackgroundPregnancy and childbirth are significant events in many women’s lives, and the prevalence of depressive symptoms increases during this...
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A case of bullous pemphigoid and renal disease after dipeptidyl peptidase 4 inhibitor administration
A 62-year-old man with type 2 diabetes was admitted because of a decrease in estimated glomerular filtration rate from 72 to 17.5 mL/min/1.73 m 2 in...
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Smoking status, cadmium, and chronic kidney disease
BackgroundChronic kidney disease (CKD) affects 10% of the general population in Western countries. Currently, CKD cannot be cured and there are only...
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Occurrence of Monoclonal Band in Alpha Region on Serum Electrophoresis in Multiple Myeloma: A Diagnostic Conundrum
The presence of an M-band in serum and/or urine electrophoresis is a crucial diagnostic indicator for multiple myeloma and other plasma cell...
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Identifying blood biomarkers for type 2 diabetes subty**: a report from the ORIGIN trial
Aims/hypothesisIndividuals with diabetes can be clustered into five subtypes using up to six routinely measured clinical variables. We hypothesised...
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Is tear proteome profile a predictor of develo** uveitis in ANA-positive patients with oligoarticular juvenile idiopathic arthritis?
PurposeAlthough less than one-third of anti-nuclear antibody (ANA) positive patients with oJIA develop uveitis, ANA positivity is still the most...