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  1. Alcohol-Associated Liver Disease: Evolving Concepts and Treatments

    Alcohol is a prominent cause of liver disease worldwide with higher prevalence in developed nations. The spectrum of alcohol-associated liver disease...

    David Stephen Prince, Emily Nash, Ken Liu in Drugs
    Article Open access 25 September 2023
  2. Designing clinical trials to address alcohol use and alcohol-associated liver disease: an expert panel Consensus Statement

    Most patients with alcohol-associated liver disease (ALD) engage in heavy drinking defined as 4 or more drinks per day (56 g) or 8 (112 g) or more...

    Brian P. Lee, Katie Witkiewitz, ... Mack C. Mitchell in Nature Reviews Gastroenterology & Hepatology
    Article 07 June 2024
  3. Treatment of alcohol use disorder in patients with alcohol-associated liver disease: Innovative approaches and a call to action

    Alcohol-associated liver disease is currently the leading cause of liver transplantation and liver deaths both in Europe and the United States....

    Lamia Y. Haque, Paola Zuluaga, ... Daniel Fuster in Addiction Science & Clinical Practice
    Article Open access 19 March 2024
  4. Metabolic dysfunction-associated fatty liver disease and heavy alcohol consumption increase mortality:A nationwide study

    Background

    The effects of excessive alcohol consumption on the prognosis of metabolic dysfunction-associated fatty liver disease (MAFLD) remain...

    So Hyun Cho, Seohyun Kim, ... Jae Hyeon Kim in Hepatology International
    Article 28 May 2024
  5. Bariatric Surgery Is Associated with Alcohol-Related Liver Disease and Psychiatric Disorders Associated with AUD

    Background/Aims

    Bariatric surgery can increase the risk of addictive disorders and nutritional deficiencies. The aim of this study was to evaluate the...

    Edilmar Alvarado-Tapias, David Marti-Aguado, ... Ramon Bataller in Obesity Surgery
    Article Open access 07 March 2023
  6. Micro-scale vertebral features in postmenopausal women with alcohol-associated and metabolic-associated fatty liver disease: ex vivo bone quality analyses

    Purpose

    Although epidemiological studies indicate increased fracture risk in women with alcohol-associated liver disease (AALD) and...

    J. Jadzic, P. Milovanovic, ... D. Djonic in Journal of Endocrinological Investigation
    Article 10 June 2023
  7. Cytotoxic NK cells phenotype and activated lymphocytes are the main characteristics of patients with alcohol-associated liver disease

    T cells, natural killer (NK) and NKT cells have opposing actions in the development of alcohol-associated liver fibrosis. We aimed to evaluate the...

    Coral Zurera-Egea, Aina Teniente-Serra, ... Paola Zuluaga in Clinical and Experimental Medicine
    Article Open access 01 July 2023
  8. The intersection between alcohol-related liver disease and nonalcoholic fatty liver disease

    Nonalcoholic fatty liver disease (NAFLD) and alcohol-related liver disease (ALD) are the leading causes of chronic liver disease worldwide. NAFLD and...

    Luis Antonio Díaz, Juan Pablo Arab, ... Marco Arrese in Nature Reviews Gastroenterology & Hepatology
    Article 15 August 2023
  9. Differences in Bacterial Translocation and Liver Injury in Ethanol Versus Diet-Induced Liver Disease

    Background

    Alcohol-associated liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH) are two of the...

    Cynthia L. Hsu, Yanhan Wang, ... Bernd Schnabl in Digestive Diseases and Sciences
    Article 20 February 2023
  10. Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH)

    Non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) has become the leading cause of liver disease worldwide. NASH, an advanced form of...

    **aohan Xu, Kyle L. Poulsen, ... **bo Yang in Signal Transduction and Targeted Therapy
    Article Open access 13 August 2022
  11. Independent Associations of Aortic Calcification with Cirrhosis and Liver Related Mortality in Veterans with Chronic Liver Disease

    Introduction

    Abdominal aortic calcifications (AAC) are incidentally found on medical imaging and useful cardiovascular burden approximations. The...

    Steven R. Horbal, Patrick X. Belancourt, ... Grace L. Su in Digestive Diseases and Sciences
    Article Open access 23 April 2024
  12. Addiction and Liver Disease: Exploring the Complex Relationship and Implications for Clinical Management

    Purpose of Review

    The review focuses on addressing substance use disorders in individuals with chronic liver disease, specifically alcohol, tobacco,...

    David Hudson, Nisha Howarth, ... Juan Pablo Arab in Current Hepatology Reports
    Article 23 January 2024
  13. Lifestyle interventions in nonalcoholic fatty liver disease

    Nonalcoholic fatty liver disease (NAFLD) is a dynamic chronic liver disease that develops in close association with metabolic irregularities. Between...

    Zobair M. Younossi, Shira Zelber-Sagi, ... Lynn H. Gerber in Nature Reviews Gastroenterology & Hepatology
    Article 04 July 2023
  14. The Global Epidemic of Metabolic Fatty Liver Disease

    Purpose of Review

    The objective of this manuscript is to examine the current literature on the epidemiology of metabolic dysfunction-associated...

    Ethan C. Z. Lee, Vickram V. Anand, ... Anurag Mehta in Current Cardiology Reports
    Article 20 February 2024
  15. Alcohol Drinking Impacts on Adiposity and Steatotic Liver Disease: Concurrent Effects on Metabolic Pathways and Cardiovascular Risks

    Purpose of Review

    This integrative search aimed to provide a sco** overview of the relationships between the benefits and harms of alcohol drinking...

    Diego Martínez-Urbistondo, Nuria Perez-Diaz-del-Campo, ... J. Alfredo Martínez in Current Obesity Reports
    Article Open access 23 March 2024
  16. Chronic Liver Disease in the Older Patient—Evaluation and Management

    Purpose of Review

    As our population ages, the number of elderly patients with advanced chronic liver disease (ACLD) will increase. In this review we...

    Daniel Anthony DiLeo, Tolga Gidener, Ayse Aytaman in Current Gastroenterology Reports
    Article 22 November 2023
  17. Liver and atherosclerotic risks of patients with cryptogenic steatotic liver disease

    Background and aims

    In 2023, a new nomenclature of “metabolic associated steatotic liver disease” (MASLD) has emerged by incorporating...

    Shao-Wen Wang, Tsung-Han Hsieh, ... Jia-Horng Kao in Hepatology International
    Article 16 January 2024
  18. Prevalence of Nonalcoholic Fatty Liver Disease [NAFLD] and Metabolic dysfunction associated Fatty Liver Disease [MAFLD] in patients with Irritable Bowel Syndrome [IBS]

    Irritable Bowel Syndrome (IBS) and Nonalcoholic Fatty Liver Disease (NAFLD) are among most sought gastrointestinal and liver related conditions...

    Md. Musab Khalil, Sirajam Munira, ... Md. Golam Kibria in SN Comprehensive Clinical Medicine
    Article 18 April 2024
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