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Showing 1-20 of 332 results

  1. Value of [18F]AlF-NOTA-FAPI-04 PET/CT for differential diagnosis of malignant and various inflammatory lung lesions: comparison with [18F]FDG PET/CT

    Objective

    Uptake of the imaging tracers [ 18 F]AlF-NOTA-FAPI-04 and [ 18 F]FDG varies in some inflammatory lesions, which may result in false-positive...

    Kailin Qiao, Xueting Qin, ... Yuchun Wei in European Radiology
    Article 05 September 2023

  2. [18F]AlF-NOTA-PCP2: a novel PET/CT tracer for enhanced PD-L1 heterogeneity imaging and comparative analysis with [18F]AlF-NOTA-WL12 in glioblastoma xenografts

    Purpose

    The unsatisfactory efficacy of PD-L1 antibodies in glioblastoma (GBM) is largely due to the temporal and spatial heterogeneity of PD-L1...

    Yong Wang, Yang Zhang, ... Man Hu in European Journal of Nuclear Medicine and Molecular Imaging
    Article 07 May 2024

  3. Prospective comparison of [18F]AlF-NOTA-octreotide PET/MRI to [68Ga]Ga-DOTATATE PET/CT in neuroendocrine tumor patients

    Background

    Fluorine-18-labeled SSAs have the potential to become the next-generation tracer in SSTR-imaging in neuroendocrine tumor (NET) patients...

    Lennert Boeckxstaens, Elin Pauwels, ... Christophe M. Deroose in EJNMMI Research
    Article Open access 01 June 2023

  4. Clinical value of [18F]AlF-NOTA-FAPI-04 PET/CT for assessing early-stage liver fibrosis in adult liver transplantation recipients compared with chronic HBV patients

    Aims

    To investigate the clinical value and performance of [ 18 F]AlF-NOTA-FAPI-04 PET/CT in assessing early-stage liver fibrosis in liver...

    Wei Rao, **ao-han Fang, ... Man **e in Japanese Journal of Radiology
    Article 06 February 2024

  5. Early detection of radiation-induced myocardial damage by [18F]AlF-NOTA-FAPI-04 PET/CT imaging

    Purpose

    Retrospective analysis revealed increased [ 18 F]AlF-NOTA-FAPI-04 uptake in the myocardium of patients with esophageal squamous cell cancer...

    Yuchun Wei, Yuhong Sun, ... **ming Yu in European Journal of Nuclear Medicine and Molecular Imaging
    Article 19 September 2022

  6. A comparison of [18F]AlF- and 68Ga-labeled dual targeting heterodimer FAPI-RGD in malignant tumor: preclinical evaluation and pilot clinical PET/CT imaging

    Abstract

    Due to the heterogeneity of tumors, strategies to improve the effectiveness of dual-targeting tracers in tumor diagnostics have been...

    Nan Liu, Qiang Wan, ... Wei Zhang in European Journal of Nuclear Medicine and Molecular Imaging
    Article 22 January 2024

  7. [18F] AlF-NOTA-FAPI-04 PET/CT can predict treatment response and survival in patients receiving chemotherapy for inoperable pancreatic ductal adenocarcinoma

    Purpose

    We investigated whether uptake of [ 18 F] AlF-NOTA-FAPI-04 on positron emission tomography/computed tomography (PET/CT) could predict treatment...

    Ziyuan Zhu, Kai Cheng, ... **bo Yue in European Journal of Nuclear Medicine and Molecular Imaging
    Article 17 June 2023

  8. [18F]AlF-NOTA-FAPI-04: FAP-targeting specificity, biodistribution, and PET/CT imaging of various cancers

    Purpose

    In this pilot study, we developed a new tracer, [ 18 F]AlF-labeled FAPI-04 chelated with NOTA, denoted as [ 18 F]AlF-NOTA-FAPI-04, and tested the...

    Yuchun Wei, **song Zheng, ... **ming Yu in European Journal of Nuclear Medicine and Molecular Imaging
    Article 09 March 2022

  9. [18F]AlF-NOTA-FAPI-04 PET/CT uptake in metastatic lesions on PET/CT imaging might distinguish different pathological types of lung cancer

    Purpose

    Heterogeneity is found in the tumor microenvironment among different pathological types of tumors. Radionuclide-labeled...

    Yuchun Wei, Kai Cheng, ... Shuanghu Yuan in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 06 December 2021

  12. [18F] AlF‑NOTA‑FAPI‑04 PET/CT as a promising tool for imaging fibroblast activation protein in gastrointestinal system cancers: a prospective investigation of comparative analysis with 18F-FDG

    Purpose

    The radiopharmaceutical [ 18 F]AlF-NOTA-FAPI-04 presents a promising alternative to 68 Ga-FAPI owing to its relatively longer half-life. This...

    Li** Yang, Shichuan Xu, ... Kezheng Wang in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 05 August 2023

  13. Evaluation of 18F-AlF-NOTA-octreotide for imaging neuroendocrine neoplasms: comparison with 68Ga-DOTATATE PET/CT

    Objective

    To evaluate the diagnostic efficacy of 18 F-AlF-NOTA-octreotide ( 18 F-OC) PET/CT compared with that of 68 Ga-DOTATATE PET/CT.

    Materials and...
    Jiale Hou, Tingting Long, ... Shuo Hu in EJNMMI Research
    Article Open access 09 June 2021

  14. Early, non-invasive detection of radiation-induced lung injury using PET/CT by targeting CXCR4

    Purpose

    Radiation-induced lung injury (RILI) is a severe side effect of radiotherapy (RT) for thoracic malignancies and we currently lack established...

    **li Pei, Kai Cheng, ... Jie Liu in European Journal of Nuclear Medicine and Molecular Imaging
    Article 30 November 2023

  15. Evaluation of the safety, biodistribution, dosimetry of [18F]AlF-NOTA-LM3 and head-to-head comparison with [68Ga]Ga-DOTATATE in patients with well-differentiated neuroendocrine tumors: an interim analysis of a prospective trial

    Purpose

    18 F-labelled somatostatin receptor (SSTR) analogs offer several advantages over 68 Ga in terms of yield, cost, spatial resolution and...

    Meixi Liu, Chao Ren, ... Li Huo in European Journal of Nuclear Medicine and Molecular Imaging
    Article 15 June 2024

  16. Comparison of renal clearance of [18F]AlF-RESCA-HER2-BCH and [18F]AlF-NOTA-HER2-BCH in mice and breast cancer patients

    Purpose

    A novel HER2 affibody-based molecular probe, [ 18 F]AlF-RESCA-HER2-BCH, was developed for reducing renal uptake, evaluated, and compared with [ 18...

    Jiayue Liu, **aoyi Guo, ... Zhi Yang in European Journal of Nuclear Medicine and Molecular Imaging
    Article 24 April 2023

  17. First-in-human study of PSMA-targeting agent, [18F]AlF-P16-093: dosimetry and initial evaluation in prostate cancer patients

    Purpose

    This is a first-in-human study to evaluate the radiation dosimetry of a new prostate-specific membrane antigen (PSMA)-targeted...

    Ruiyue Zhao, Miao Ke, ... **nlu Wang in European Journal of Nuclear Medicine and Molecular Imaging
    Article 12 January 2024

  18. High in-vivo stability in preclinical and first-in-human experiments with [18F]AlF-RESCA-MIRC213: a 18F-labeled nanobody as PET radiotracer for diagnosis of HER2-positive cancers

    Purpose

    [ 18 F]AlF-RESCA was introduced as a core particularly useful for 18 F-labeling of heat-sensitive biomolecules. However, no translational...

    Xue Qin, **aoyi Guo, ... Zhi Yang in European Journal of Nuclear Medicine and Molecular Imaging
    Article 21 September 2022

  19. Targeting CXCR4/CXCL12 axis via [177Lu]Lu-DOTAGA.(SA.FAPi)2 with CXCR4 antagonist in triple-negative breast cancer

    Purpose

    Radiopharmaceutical therapies targeting fibroblast activation protein (FAP) have shown promising efficacy against many tumor types. But...

    Guangfa Bao, Ziqiang Wang, ... **aohua Zhu in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 08 April 2024

  20. Comparison of [18F]-OC PET/CT and contrast-enhanced CT/MRI in the detection and evaluation of neuroendocrine neoplasms

    Objectives

    Gallium-68 ( 68 Ga)–labeled somatostatin analog (SSA) PET imaging has been widely used in clinical practice of neuroendocrine neoplasms...

    Donghe Chen, Shuye Yang, ... **nhui Su in European Journal of Nuclear Medicine and Molecular Imaging
    Article 27 March 2023
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