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Validation of administrative claims to identify ultrasound enhancing agent use
BackgroundUltrasound enhancing agents (UEAs) are an invaluable adjunct to stress and transthoracic echocardiography (STE) to improve left ventricular...
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Validation of algorithms to identify colorectal cancer patients from administrative claims data of a Japanese hospital
BackgroundAdministrative claims data are a valuable source for clinical studies; however, the use of validated algorithms to identify patients is...
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A Review of Research Studies Using Data from the Administrative Claims Databases in Japan
BackgroundIn Japan, several research studies have used administrative claims databases. However, no study has compared the studies conducted in each...
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Validation of Algorithms to Identify Bone Metastases Using Administrative Claims Data in a Japanese Hospital
BackgroundValidated coding algorithms are essential to generate high-quality, real-world evidence from claims data studies.
Objective ...
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CYP2D6 Substrate Dispensing Among Patients Dispensed Mirabegron: An Administrative Claims Analysis
BackgroundOveractive bladder (OAB) is characterized by the presence of bothersome urinary symptoms. Pharmacologic treatment options for OAB include...
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Exact-matching algorithms using administrative health claims database equivalence factors for real-world data analysis based on the target trial emulation framework
Real-world data have become increasingly important in medical science and healthcare. A new, effective, and practically feasible statistical design...
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Prevalence of hypertensive diseases and treated hypertensive patients in Japan: A nationwide administrative claims database study
We investigated the prevalence of hypertensive patients and treated hypertensive patients using a Japanese nationwide administrative claims database....
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Early Detection of Adverse Drug Reaction Signals by Association Rule Mining Using Large-Scale Administrative Claims Data
IntroductionAdverse drug reactions (ADRs) are a leading cause of mortality worldwide and should be detected promptly to reduce health risks to...
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Multikinase Inhibitor Treatment Patterns for Advanced Thyroid Cancer in Japan: An Administrative Claims Database Study
BackgroundThe multikinase inhibitors (MKIs) sorafenib, lenvatinib, and vandetanib are approved for advanced thyroid cancer (TC) in Japan. How...
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Clinical and Economic Burden of Herpes Zoster in Patients with Rheumatoid Arthritis: A Retrospective Cohort Study Using Administrative Claims
ObjectiveTo estimate the incremental healthcare resource utilization (HRU) and cost burden posed by herpes zoster (HZ) in adult patients with...
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Fracture definitions in observational osteoporosis drug effects studies that leverage healthcare administrative (claims) data: a sco** review
SummaryHealthcare administrative (claims) data are commonly utilized to estimate drug effects. We identified considerable heterogeneity in fracture...
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Adaptation and validation of a coding algorithm for the Charlson Comorbidity Index in administrative claims data using the SNOMED CT standardized vocabulary
ObjectivesThe Charlson comorbidity index (CCI), the most ubiquitous comorbid risk score, predicts one-year mortality among hospitalized patients and...
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Disease Progression Stages and Burden in Patients with Duchenne Muscular Dystrophy Using Administrative Claims Supplemented by Electronic Medical Records
IntroductionThis study aims to identify stages of Duchenne muscular dystrophy (DMD) and assess the disease burden by progression stage using...
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Measuring Costs of Cardiovascular Disease Prevention for Patients with Familial Hypercholesterolemia in Administrative Claims Data
IntroductionFamilial hypercholesterolemia is a common genetic condition that significantly increases an individual’s risk of cardiovascular events...
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Renin–angiotensin–aldosterone system inhibitors are associated with improved paclitaxel-induced peripheral neuropathy in lung cancer: a study using administrative claims data
PurposeChemotherapy-induced peripheral neuropathy (CIPN) has been reported to reduce patients’ quality of life and impair cancer treatment by causing...
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Improved Prediction of Body Mass Index in Real-World Administrative Healthcare Claims Databases
IntroductionTo continue closing the gap between the predictive modeling and its real-world application, we report a new data-to-prediction pipeline...
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Identifying Patients with Group 3 Pulmonary Hypertension Associated with COPD or ILD Using an Administrative Claims Database
BackgroundGroup 3 pulmonary hypertension (PH) describes a subpopulation of patients with PH due to chronic lung disease and/or hypoxia, with chronic...
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Cardiotoxicity from bruton tyrosine kinase inhibitors (BTKi)—an analysis of an administrative health claims database
BackgroundFirst generation Bruton tyrosine kinase inhibitors (BTKi) such as ibrutinib have been associated with cardiovascular toxicities. Newer...
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Comparative Treatment Persistence and Adherence to Endothelin Receptor Antagonists Among Patients with Pulmonary Arterial Hypertension in Japan: A Real-World Administrative Claims Database Study
IntroductionReal-world data on the comparative effectiveness of endothelin receptor antagonists (ERAs; macitentan, bosentan, ambrisentan) for...
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Investigating the association between metabolic syndrome conditions and perinatal mental illness: a national administrative claims study
BackgroundAlthough the association between mental disorder and metabolic syndrome as a bidirectional relationship has been demonstrated, there is...