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Terapia del carcinoma corticosurrenalico dopo fallimento del mitotane
Mitotane is the only approved drug in the management of adrenocortical carcinoma (ACC). Mitotane can be administered in the adjuvant setting in...
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EDP-mitotane in children: reassuring evidence of reversible side-effects and neurotoxicity
Adrenocortical carcinoma affects one in 5 million children each year. Since prognosis for children older than 4 years is limited, clinicians often...
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Clinical management and outcomes associated with etoposide, doxorubicin, and cisplatin plus mitotane treatment in metastatic adrenocortical carcinoma: a single institute experience
BackgroundAdrenocortical carcinoma (ACC) is a rare and aggressive disease that is often diagnosed at an advanced stage. There is no standard...
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Oncocytic adrenocortical neoplasm of borderline uncertain malignant potential diagnosed after robot-assisted adrenalectomy case report
BackgroundAdrenal incidentalomas are radiologically discovered tumors that represent a variety of pathologies, with the diagnosis clinched only on...
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Massive adrenocortical carcinoma presenting as peripheral edema: a case report
BackgroundAdrenocortical carcinoma is a rare, but potentially lethal, malignancy that is usually detected as an incidental finding on abdominal...
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Pregnancy in patients with adrenocortical carcinoma: a case-based discussion
Although adrenocortical carcinoma (ACC) during pregnancy is rare, a retrospective review of a case series at our hospital revealed that almost one...
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Different management of adrenocortical carcinoma in children compared to adults: is it time to share guidelines?
Pediatric and adult adrenocortical carcinomas differ in many respects but treatment is often similar in both age groups. The Journal of Clinical...
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Defining Optimal Management of Non-metastatic Adrenocortical Carcinoma
BackgroundAdrenocortical carcinoma (ACC) is an aggressive, deadly malignancy. Resection remains the primary treatment; however, there is conflicting...
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Mitotane (Lysodren®) in der Therapie des Nebennierenrindenkarzinoms
Mitotane, or o,p’-DDD (European tradename: Lysodren®, HRA Pharma, Paris, France), is an orphan drug for the adjuvant therapy of adrenocortical...