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The correlation between sperm percentage with a small acrosome and unexplained in vitro fertilization failure
PurposeSince the unexplained in vitro fertilization failure occurs frequently, it is of great importance and clinical value to identify potential...
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Homozygous mutation in SLO3 leads to severe asthenoteratozoospermia due to acrosome hypoplasia and mitochondrial sheath malformations
BackgroundPotassium channels are important for the structure and function of the spermatozoa. As a potassium transporter, the mSlo3 is essential for...
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Clinical Utility of Sperm Function Tests in Predicting Male Fertility: A Systematic Review
Routine semen analysis provides considerable information regarding sperm parameters; however, it is not solely adequate to predict male fertility...
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Advances in the study of genetic factors and clinical interventions for fertilization failure
Fertilization failure refers to the failure in the pronucleus formation, evaluating 16-18 h post in vitro fertilization or intracytoplasmic sperm...
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Cannabidiol impairs sperm quality and function in adult mice
BackgroundConsidering the growing therapeutic use of cannabidiol as well as the presence of cannabinoid receptors in sperm and its possible genotoxic...
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Camellia oil with its rich in fatty acids enhances post-thawed boar sperm quality
BackgroundBoar sperm are highly susceptible to specific conditions during cryopreservation, leading to a significant decrease in their fertilizing...
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Truncating PICK1 Variant Identified in Azoospermia Affected Mitochondrial Dysfunction in Knockout Mice
ObjectiveThe protein interacting with C kinase 1 ( PICK1 ) plays a critical role in vesicle trafficking, and its deficiency in sperm cells results in...
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Live motile sperm sorting device for enhanced sperm-fertilization competency: comparative analysis with density-gradient centrifugation and microfluidic sperm sorting
PurposeA live motile sperm sorting device (LensHooke ® CA0) developed to prevent the deleterious effects of centrifugation was evaluated...
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A loss-of-function variant in SSFA2 causes male infertility with globozoospermia and failed oocyte activation
Globozoospermia (OMIM: 102530) is a rare type of teratozoospermia (< 0.1%). The etiology of globozoospermia is complicated and has not been fully...
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Toxicological outcome of phthalate exposure on male fertility: Ameliorative impacts of the co-administration of N-acetylcysteine and zinc sulfate in rats
BackgroundReports have shown that humans are consistently exposed to environmental toxicants such as phthalate (PHT) during their daily activities....
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Antimicrobial peptides and proteins as alternative antibiotics for porcine semen preservation
BackgroundAntimicrobial resistance (AMR) is nowadays a major emerging challenge for public health worldwide. The over- and misuse of antibiotics,...
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Magnetic bead-based separation of sperm cells from semen-vaginal fluid mixed stains using an anti-ACRBP antibody
Forensic DNA analysis of semen-vaginal fluid mixed stains is essential and necessary in sexual assault cases. Here, we used a magnetic bead...
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Hsp90 modulates human sperm capacitation via the Erk1/2 and p38 MAPK signaling pathways
BackgroundHeat shock protein 90 (Hsp90) is a highly abundant eukaryotic molecular chaperone that plays important roles in client protein maturation,...
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Flow-cytometric analysis of membrane integrity of stallion sperm in the face of agglutination: the “zombie sperm” dilemma
PurposeTo define the effect of sperm agglutination, associated with incubation under capacitating conditions, on accuracy of membrane assessment via...
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A comprehensive investigation of human endogenous retroviral syncytin proteins and their receptors in men with normozoospermia and impaired semen quality
PurposeThe study aims to investigate first the presence of Syncytin 2 and its receptor, MFSD2, in human sperm, and second whether the expressions of...
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Protein profiling of testicular tissue from boars with different levels of hyperactive sperm motility
Hyperactive sperm motility is important for successful fertilization. In the present study, a proteome profiling approach was performed to identify...
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Protective Effect of Aloe vera (L.) on Diabetes-Induced Oxidative Stress Linked Spermiological Co-Morbidity in Human and Rat: An In-Vitro Analysis
Diabetes linked reproductive complications are rising problems nowadays. The study focused on the protective efficacy of Aloe vera (L.) on sperm cell...
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Histone Methylation Regulates Gene Expression in the Round Spermatids to Set the RNA Payloads of Sperm
Gene expression during spermatogenesis undergoes significant changes due to a demanding sequence of mitosis, meiosis, and differentiation. We...
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Supplementation of melatonin to cooling and freezing extenders improves canine spermatozoa quality measures
BackgroundSperm freezing and cold storage are the two most common assisted reproductive technologies in the canine breeding industry. The...
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The Detection of CatSper1 and CatSper3 Expression in Men with Normozoospermia and Asthenoteratozoospermia and Its Association with Sperm Parameters, Fertilization Rate, Embryo Quality
CatSper affects sperm function and male fertilization capacity markers, including sperm motility and egg penetration. The study has aimed to evaluate...