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Nontuberculous mycobacteria testing and culture positivity in the United States
BackgroundNontuberculous mycobacteria (NTM) are environmental bacteria which may cause chronic lung disease. The prevalence of NTM pulmonary...
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The Role of Cartridge-Based Nucleic Acid Amplification Test (CBNAAT), Line Probe Assay (LPA), Liquid Culture, Acid-Fast Bacilli (AFB) Smear and Histopathology in the Diagnosis of Osteoarticular Tuberculosis
BackgroundThere is a paucity of data on the role of molecular methods in the diagnosis of osteoarticular tuberculosis. The present study was...
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Impact of randomized blinded rechecking program on the performance of the AFB Microscopy Laboratory Network in Uganda: a decadal retrospective study
BackgroundSmear microscopy has remained the initial diagnostic test for presumptive tuberculosis (TB) patients in health facilities without the World...
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Concurrent severe pulmonary tuberculosis with Evans syndrome: a case report with literature review
BackgroundTuberculosis is a bacterial infection involving multiple organs and systems. Its hematological presentation mainly includes anemia and...
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Pathomorphological characteristics of tuberculous placenta and its clinical implication
BackgroundThe study of pathologic diagnosis of placental TB is rare. The aim of this study is analyzing the pathomorphological characteristics of...
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Report of renal allograft tuberculosis a decade after transplant: challenges in diagnosis and management
Post-transplant infections constitute an important cause of morbidity and mortality in renal transplant recipients worldwide. Tuberculosis (TB)...
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Miliary meningeal tuberculosis — an unusual imaging presentation for an early definitive diagnosis
PurposeTuberculous meningitis (TBM) causes significant morbidity and mortality in young children. Early treatment can be initiated with magnetic...
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Species identification and drug susceptibility testing of non-tuberculous mycobacteria by Line Probe Assay in Lambaréné, Gabon—a cross-sectional study
BackgroundNon-tuberculous mycobacteria (NTM) are a group of bacteria that cause rare lung infections and are increasingly recognized as causative...
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Maximizing Yield and Speed of Fungal Pathogen Identification with Molecular Testing Performed Directly on Patient Specimens
Purpose of ReviewMolecular assays for fungal pathogen detection directly in patient specimens represent valuable diagnostic tools, with the potential...
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Unveiling foot tuberculosis as an under-recognized source of foot pain
PurposeFoot tuberculosis is a rare form of osteoarticular tuberculosis, accounting for less than 1% of cases. It presents unique diagnostic...
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Mycobacterial Spindle Cell Pseudotumor of the Nasal Cavity
BackgroundMycobacterial spindle cell pseudotumor (MSCP) represents an uncommon tumor-like proliferation associated with nontuberculous mycobacterial...
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A case series of co-infection in Mycobacterium tuberculosis and other pathogens: insights from nanopore sequencing
BackgroundTuberculosis (TB) continues to be a major global health burden, and co-infection with other pathogens further complicates the diagnosis and...
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Aortic endograft infection by Mycobacterium abscessus subsp. massiliense with acquired clarithromycin resistance: a case report
BackgroundMycobacterium abscessus subsp. massiliense (MMA) comprises a group of non-tuberculous, rapidly growing mycobacteria. Although MMA can...
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Comparison of microscopic and xpert MTB diagnoses of presumptive mycobacteria tuberculosis infection: retrospective analysis of routine diagnosis at Cape Coast Teaching Hospital
IntroductionTuberculosis is a global health problem that causes 1. 4 million deaths every year. It has been estimated that sputum smear-negative...
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Emerging Applications of Artificial Intelligence in Dermatopathology
Purpose of ReviewArtificial intelligence (AI) is revolutionizing health care – transforming how physicians evaluate, diagnose, and manage a wide...
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Nocardia brain abscess in a patient with diabetes: a case report
BackgroundNocardia are aerobic Gram-positive bacilli that can invade multiple organ systems, including the brain and lungs. It is most frequently...
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Differentiating gastrointestinal tuberculosis and Crohn's disease- a comprehensive review
Gastrointestinal Tuberculosis (GITB) and Crohn’s disease (CD) are both chronic granulomatous diseases with a predilection to involve primarily the...
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Spot specimen testing with GeneXpert MTB/RIF results compared to morning specimen in a programmatic setting in Cotonou, Benin
BackgroundThe diagnosis of tuberculosis (TB) using smear microscopy has been based on testing two specimens: one spot and one early morning sputa....
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Non-pulmonary Disseminated Tuberculosis Complicated by Constrictive Pericarditis and Cutaneous Gumma
A 23-year-old previously healthy male presented to the hospital with symptoms of heart failure. He was diagnosed with pericarditis and found to have...
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Comorbidity and drug resistance of smear-positive pulmonary tuberculosis patients in the yi autonomous prefecture of China: a cross-sectional study
BackgroundTuberculosis (TB) has a high morbidity and mortality rate, and its prevention and treatment focus is on impoverished areas. The Liangshan...
