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Two cases of childhood absence epilepsy who showed seizure disappearance after ethosuximide drug eruption
BackgroundRecent studies suggest potential roles of immune response in the pathophysiology of epilepsy. Anti-seizure medications (ASMs) are known to...
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First seizure in elderly patients: Need to treat? Evidence from a retrospective study
BackgroundThe risk of seizure recurrence after a first unprovoked epileptic seizure is reported to be approximately 40%. Little is known about the...
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Seizure clusters: diagnostic and therapeutic advances
Epilepsy affects 45.9 million people globally. For individuals with epilepsy who continue to have seizures, up to half experience seizure clusters....
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Benzodiazepines for the Treatment of Seizure Clusters
Patients with epilepsy may experience seizure clusters, which are described by the US Food and Drug Administration (FDA) as intermittent, stereotypic...
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Absence seizures in lesion-related epilepsy
BackgroundIn the new International League Against Epilepsy (ILAE) classification of seizure types, generalized seizures such as absence seizures...
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Towards trustworthy seizure onset detection using workflow notes
A major barrier to deploying healthcare AI is trustworthiness. One form of trustworthiness is a model’s robustness across subgroups: while models may...
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Primary vs. pre-emptive anti-seizure medication prophylaxis in anti-CD19 CAR T-cell therapy
IntroductionSeizures may occur in up to 30% of non-Hodgkin lymphoma patients who received anti-CD19 CAR T-cell therapy, yet the optimal anti-seizure...
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Evaluation of Seizure Risk in Infants After Cardiopulmonary Bypass in the Absence of Deep Hypothermic Cardiac Arrest
BackgroundGuidelines recommend evaluation for electrographic seizures in neonates and children at risk, including after cardiopulmonary bypass (CPB)....
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Sentinel seizure heralding Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease
BackgroundIsolated seizure as a manifestation of myelin oligodendrocyte antibody-associated disease (MOGAD) has rarely been reported previously.
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Intracranial intraoperative radiotherapy (IORT): evaluation of electrocorticography and peri-operative seizure risk
BackgroundIntra-operative radiotherapy (IORT) for brain metastases (BMs) and primary brain tumors has emerged as an adjuvant radiation modality that...
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Treatment of Seizure Clusters in Epilepsy: A Narrative Review on Rescue Therapies
Epilepsy is a common neurological disorder in the United States, affecting approximately 1.2% of the population. Some people with epilepsy may...
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Leukocyte differential gene expression prognostic value for high versus low seizure frequency in temporal lobe epilepsy
BackgroundThis study was performed to test the hypothesis that systemic leukocyte gene expression has prognostic value differentiating low from high...
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Electrographic monitoring for seizure detection in the neonatal unit: current status and future direction
AbstractNeonatal neurocritical intensive care is dedicated to safeguarding the newborn brain by prioritising clinical practices that promote early...
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Which parameters influence cognitive, psychiatric and long-term seizure outcome in mesial temporal lobe epilepsy after selective amygdalohippocampectomy?
BackgroundWe aimed to analyze potentially prognostic factors which could have influence on postoperative seizure, neuropsychological and psychiatric...
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Perioperative levetiracetam for seizure prophylaxis in seizure-naive brain tumor patients with focus on neurocognitive functioning
IntroductionIn seizure-naive brain tumor patients, the efficacy of perioperative prophylactic antiepileptic drug treatment remains controversial. In...
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How electroconvulsive therapy works in the treatment of depression: is it the seizure, the electricity, or both?
We have known for nearly a century that triggering seizures can treat serious mental illness, but what we do not know is why. Electroconvulsive...
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Clinical and Laboratory Factors Related to Seizure and Serotonin Toxicity in Tramadol Intoxication: An Egyptian Study
Background and ObjectivesTramadol is a centrally acting analgesic with a lower risk of addiction compared to opioids. Tramadol overdose is becoming a...
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Driving eligibility following acute symptomatic seizure with structural brain lesion – English Version
Acute symptomatic seizures are often caused by acute structural brain lesions. However, German guidelines for driving eligibility do not cover this...
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Ketamine reduces seizure and interictal continuum activity in refractory status epilepticus: a multicenter in-person and teleneurocritical care study
BackgroundThere is not a preferred medication for treating refractory status epilepticus (RSE) and intravenous ketamine is increasingly used....
