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Clinical features and prognosis of ANCA-associated vasculitis patients who were double-seropositive for myeloperoxidase-ANCA and proteinase 3-ANCA
Anti-neutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) patients with dual positivity for proteinase 3-ANCA (PR3-ANCA) and...
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Small fiber neuropathy associated with ANCA positivity: a case series and brief literature review
IntroductionSmall fiber neuropathy [SFN] is a common peripheral neurologic disorder with a vast array of implicated etiologies. It has previously...
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Occurrence and localization of FOXP3 + cells in kidney biopsies in lupus nephritis and ANCA-associated vasculitis
The study aims to increase the understanding regarding the role of regulatory T cells (Tregs) in lupus nephritis (LN) and ANCA-associated vasculitis...
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ANCA-Associated Vasculitic Neuropathies: A Review
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a systemic disorder that frequently affects the peripheral nervous system and...
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Rare case of exostosin 1/exostosin 2-related membranous lupus nephritis concomitant with dual ANCA- and anti-GBM antibody-associated crescentic glomerulonephritis effectively diagnosed by mass spectrometry: a case report
BackgroundRecent developments in mass spectrometry (MS) have revealed target antigens for membranous nephropathy (MN), including phospholipase A2...
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MPO-ANCA-positive conversion and microscopic polyangiitis development in idiopathic interstitial pneumonia: a case report
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a systemic autoimmune disease characterized by necrotizing inflammation of the...
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Subclinical microvascular changes in ANCA-vasculitides: the role of optical coherence tomography angiography and nailfold capillaroscopy in the detection of disease-related damage
BackgroundBoth cardiovascular and complement-mediated disorders might lead to microvascular damages in anti-neutrophil cytoplasm autoantibodies...
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Serum ANCA as Disease Biomarkers: Clinical Implications Beyond Vasculitis
Usually associated with autoimmune diseases, anti-neutrophil cytoplasmic antibodies are also detected in other conditions, such as infections,...
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Diminished PD-L1 regulation along with dysregulated T lymphocyte subsets and chemokine in ANCA-associated vasculitis
ANCA-associated vasculitis (AAV) is a life-threatening disease characterized by small vessel inflammation and pathogenic self-directed antibodies....
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Histological reappraisal of IgA nephropathy: the role of glomerular pattern of injury and mesangial complement deposition
BackgroundThere is a clear need to refine the histological assessment in IgA Nephropathy (IgAN). We sought to investigate the clinical significance...
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A rare case of atypical ANCA-associated vasculitis without crescents overlap** with invasive pulmonary aspergillosis, successfully treated to remission with intravenous immunoglobulin therapy
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is life-threatening without treatment, but aggressive immunosuppression...
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IgA nephropathy with serum ANCA positivity: case series and literature review
The co-occurrence of IgA nephropathy (IgAN) and positive anti-neutrophil cytoplasmic autoantibodies (ANCA) serology is uncommon. In the present case...
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ANCA Status or Clinical Phenotype — What Counts More?
Purpose of ReviewThere is ongoing debate concerning the classification of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. That is,...
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C3 glomerulonephritis associated with ANCA positivity: a case report
BackgroundC3 glomerulopathy (C3G) is a recent disease classification that is characterized by the presence of glomerular deposits (composed of C3) in...
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A potential pathogenic role of interleukin-6 in a child with ANCA-negative pauci-immune crescentic glomerulonephritis: case report and literature review
BackgroundCrescentic glomerulonephritis is a disease characterized by severe glomerular injuries that is classified into five different pathological...
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Nephrotic-range proteinuria and membranoproliferative glomerulonephritis-like pattern caused by interferon-β1b in a patient with multiple sclerosis
Interferon-beta (IFN-β) subtypes are widely used as immunomodulatory agents for relapsing–remitting multiple sclerosis (MS). Although generally well...
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ANCA-associated vasculitis
The anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) are a group of disorders involving severe, systemic, small-vessel...
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IgA nephropathy to proliferative glomerulonephritis with monoclonal IgAκ deposits: a pattern switch
We report the case of a 31-year-old male who presented with repeated episodes of nephritic-nephrotic syndrome in concomitance with infection. IgA...
